Results 171 to 180 of about 132,111 (275)
Proteostasis of organelles in aging and disease
The FEBS Journal, EarlyView.Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi +5 more
wiley +1 more source
The FEBS Journal, EarlyView.Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia +7 more
wiley +1 more source
The FEBS Journal, EarlyView.The eukaryote‐specific N‐terminal domain (NTD) of eS31 uses two distinct strategies to maintain translation fidelity. During elongation, a positively charged “hotspot” fine‐tunes the selection of incoming aa‐tRNA. During termination, the entire NTD acts as a structural scaffold to ensure the correct positioning of the release factor eRF1.
Qingxuan Gao +3 more
wiley +1 more source
International Journal of Cosmetic Science, EarlyView.Natural antioxidants from plants, fruits, seeds and fungi combat ageing by neutralizing free radicals, boosting collagen and protecting against UV damage. Enhanced by green extraction and smart delivery systems, they offer powerful anti‐inflammatory and antimicrobial benefits.
Hossein Omidian +2 more
wiley +1 more source
Insect Molecular Biology, EarlyView.Duplication of vas genes is universally observed in aphids, and phylogenetic analysis indicates that this event predates the divergence of Aphididae and Phylloxeridae. Ap‐vas1 is germline‐specific, whereas Ap‐vas2–4 exhibit somatic expression, indicating functional divergence during aphid embryogenesis.
Gee‐Way Lin +4 more
wiley +1 more source
MiR‐155‐5p promotes endothelial–mesenchymal transition and oxidative stress in diabetic retinopathy
Journal of Diabetes Investigation, EarlyView.ABSTRACT Aims MicroRNA (miRNA) has been confirmed to be related to gene expression regulation and disease progression. However, the role of miR‐155‐5p in diabetic retinopathy remains unclear. Materials and Methods The retinal microvascular endothelial cells (RMECs) were treated with high glucose, and then the changes of miR‐155‐5p, endothelial cell ...
Wenwen Dou +4 more
wiley +1 more source
New Phytologist, EarlyView.Summary Plants and soils have been moved around the world for centuries, but invasive mushrooms receive scant attention. The Amanita muscaria species complex was introduced to South Africa in the context of forestry, but its origins, ecology and recent evolution are unstudied. We sequenced the genomes of 24 Northern and Southern Hemisphere A. muscaria,
Grant R. Nickles +39 more
wiley +1 more source
Fully Tunable Phosphorylation of RPS6A Ensures the Successful Development of Arabidopsis Seedlings
Plant, Cell &Environment, EarlyView.ABSTRACT Light enhances protein translation, enabling young seedlings to rapidly and timely acquire photosynthetic capacities. Sequential phosphorylation of ribosomal protein S6 (RPS6) was implicated in the light‐enhanced translation; however, the exact phosphorylation sites and the biological relevance of RPS6 multi‐phosphorylation in seedling ...
Yueh Cho +2 more
wiley +1 more source
Photochemistry and Photobiology, EarlyView.Gadusol‐rich extracts provide effective UVB protection and antioxidant activity in HaCaT cells and C. elegans, highlighting their potential as natural photochemoprotective agents for pharmaceutical and cosmetic applications. It also demonstrates remarkable in vitro antioxidant capacity and thermal stability over time.
Rocío Isla Naveira +9 more
wiley +1 more source
Ancestral roles of IĸB proteins in Caenorhabditis elegans
, 2021 Programa de Doctorat en Biomedicina / Tesi realitzada a l'Institut de Investigació Biomèdica de Bellvitge (IDIBELL)
openaire +2 more sources