Results 11 to 20 of about 136,350 (159)

Genome-wide characterization, evolution, structure, and expression analysis of the F-box genes in Caenorhabditis

open access: yesBMC Genomics, 2021
Background F-box proteins represent a diverse class of adaptor proteins of the ubiquitin-proteasome system (UPS) that play critical roles in the cell cycle, signal transduction, and immune response by removing or modifying cellular regulators.
Ailan Wang, Wei Chen, Shiheng Tao
doaj   +1 more source

Curcumin reduced fat accumulation in Caenorhabditis elegans

open access: yesCurrent Research in Food Science, 2021
Curcumin, the primary bioactive substance in turmeric, is known to be associated with weight loss. In this study, we employed Caenorhabditis elegans, a well-established in vivo nematode model to explore the role of curcumin in regulating lipid metabolism.
Yiren Yue   +3 more
doaj   +1 more source

Exploring the conservation of Alzheimer-related pathways between H. sapiens and C. elegans: a network alignment approach

open access: yesScientific Reports, 2021
Alzheimer disease (AD) is a neurodegenerative disorder with an –as of yet– unclear etiology and pathogenesis. Research to unveil disease processes underlying AD often relies on the use of neurodegenerative disease model organisms, such as Caenorhabditis ...
Avgi E. Apostolakou   +4 more
doaj   +1 more source

Neuronal Gα subunits required for the control of response to polystyrene nanoparticles in the range of μg/L in C. elegans

open access: yesEcotoxicology and Environmental Safety, 2021
The aim of this study was to identify Gα proteins mediating function of neuronal G protein-coupled receptors (GPCRs) in controlling the response to polystyrene nanoparticles (PS-NPs).
Yunhan Yang, Qiuli Wu, Dayong Wang
doaj   +1 more source

Tubulins in C. elegans [PDF]

open access: yes, 2018
The C. elegans tubulin family is composed of nine α-, six β-, and one γ-tubulin. Tubulins are highly conserved, functioning as α-β heterodimers that assemble into microtubules.
Hurd, Daryl D.
core   +2 more sources

Caenorhabditis elegans BAH-1 is a DUF23 protein expressed in seam cells and required for microbial biofilm binding to the cuticle. [PDF]

open access: yesPLoS ONE, 2009
The cuticle of Caenorhabditis elegans, a complex, multi-layered extracellular matrix, is a major interface between the animal and its environment. Biofilms produced by the bacterial genus Yersinia attach to the cuticle of the worm, providing an assay for
Kevin Drace   +2 more
doaj   +1 more source

The genome of Romanomermis culicivorax:revealing fundamental changes in the core developmental genetic toolkit in Nematoda [PDF]

open access: yes, 2013
Background: The genetics of development in the nematode Caenorhabditis elegans has been described in exquisite detail. The phylum Nematoda has two classes: Chromadorea (which includes C. elegans) and the Enoplea.
Altmüller, Janine   +15 more
core   +2 more sources

Immunoprecipitation of Proteins in Caenorhabditis elegans

open access: yesBio-Protocol, 2015
Immunoprecipitation (IP) is a biochemical technique to precipitate a protein out of solution using an antigen that can specifically bind to that protein.
Kevin Chan   +3 more
doaj   +1 more source

A comprehensive survey of C. elegans argonaute proteins reveals organism-wide gene regulatory networks and functions

open access: yeseLife, 2023
Argonaute (AGO) proteins associate with small RNAs to direct their effector function on complementary transcripts. The nematode Caenorhabditis elegans contains an expanded family of 19 functional AGO proteins, many of which have not been fully ...
Uri Seroussi   +9 more
doaj   +1 more source

The kunitz domain protein BLI-5 plays a functionally conserved role in cuticle formation in a diverse range of nematodes [PDF]

open access: yes, 2010
The cuticle of parasitic nematodes performs many critical functions and is essential for proper development and for protection from the host immune response.
Antony P. Page   +43 more
core   +1 more source

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