Results 191 to 200 of about 136,487 (292)

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically diverse <i>Caenorhabditis</i> nematodes. [PDF]

Elife
Banse SA, Sedore CA, Coleman-Hulbert A, Johnson E, Onken B, Hall D, Segerdell E, Jackson EG, Song Y, Osman HC, Xue J, Basttistoni E, Guo S, Foulger A, Achanta M, Sheikh M, Fitzgibbon T, Willis JH, Woodruff GC, Driscoll M, Lithgow G, Phillips PC.   +21 more
europepmc   +1 more source

Mycovirus Vector‐Mediated RNAi for Effective Gene Knockdown in Pine Wood Nematodes

Plant Biotechnology Journal, EarlyView.
Ruiling Bian, Yifan Zhang, Zhihao Zhang, Yuchi Bai, Peiqin Li, Guanghui Tang, Lihua Guo, Huan Liu, Ida Bagus Andika, Qiaoxia Shang, Liying Sun   +10 more
wiley   +1 more source

Distinct contributions of O‐acetylserine sulfhydrylases to cysteine biosynthesis in Pseudomonas aeruginosa

Protein Science, Volume 35, Issue 3, March 2026.
Abstract Cysteine biosynthesis in bacteria proceeds primarily via the de novo pathway, involving serine acetyltransferase (CysE) and O‐acetylserine sulfhydrylase (OASS). This pathway is absent in humans, and its inhibition impairs microbial fitness, virulence, and antibiotic resistance, making its enzymes attractive antimicrobial targets. Most bacteria
Noemi Massa, Flavia Catalano, Silvia Fruncillo, Francesca Troilo, Marta Mellini, Filippo Favretto, Livia Leoni, Giordano Rampioni, Alessandro Giuffrè, Adele di Matteo, Alessandra Astegno   +10 more
wiley   +1 more source

Coincident evolution and functional adaptation of the taxonomically restricted genes ivph-3 and gon-14 in Caenorhabditis nematodes. [PDF]

Biol Open
Jhaveri N, Gupta B, Chamberlin HM.
europepmc   +1 more source

Single‐cell mitochondrial lineage tracing: Opportunities and challenges

Quantitative Biology, Volume 14, Issue 1, March 2026.
Abstract Lineage tracing using endogenous mitochondrial DNA (mtDNA) variants holds great promise for reconstructing the lineage histories of individual cells, with broad applications in oncology, developmental biology, and regenerative medicine.
Siqi Li, Kun Wang, Xin Wang, Zheng Hu
wiley   +1 more source

Ecotoxicological Evaluation of the Antimicrobial Butylparaben in Edaphic Organisms Using Multiple Biomarkers

Environmental Toxicology, Volume 41, Issue 3, Page 176-189, March 2026.
ABSTRACT Butylparaben (BuP) recurrently contaminates soils worldwide, mainly by incorporating sewage sludge into cultivated areas, using wastewater in irrigation, and leaching contaminated soils. However, there are few studies on the ecotoxicological effects of this paraben on edaphic organisms.
Lorena Maihury Santos Tsubouchi, Edson Araújo de Almeida, Diane Scapin, Anna Karolina Gomes Oliveira, Cassiano Aparecido de Souza, Diego Espirito Santo, Carmem Lúcia Henrich, Ana Elisa Maehashi, Gideã Taques Tractz, Craig Allan Downs, Osvaldo Valarini Junior, Regiane da Silva Gonzalez, Elisângela Düsman, Ana Paula Peron   +13 more
wiley   +1 more source

The FMRFamide-like peptide FLP-11 regulates the production and secretion of the TGF-β-like protein DAF-7 during Caenorhabditis elegans larval development. [PDF]

Sci Rep
Uegaki R, Maega S, Ono M, Bito T, Iwasaki T, Shiraishi A, Satake H, Kawano T.   +7 more
europepmc   +1 more source

Diverse reference genomes detect variants in the US winter wheat

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract The first hexaploid bread wheat reference genome from Chinese Spring was released in 2018 by the International Wheat Genome Sequencing Consortium and is considered as the industry standard reference. To explore the effects of different reference genomes on variant discovery, 29 hexaploid bread wheat (Triticum aestivum L.) cultivars from the ...
Kyle Parker, Zhen Wang, Yahya Rauf, Liangliang Gao, Jesse Poland, Jackie Rudd, Amir Ibrahim, Shuyu Liu   +7 more
wiley   +1 more source

Variation in Social Feeding Behaviors and Interactions Among <i>Caenorhabditis Nematodes</i>. [PDF]

Ecol Evol
Haskell D, Palo J, Eugene RFH, Large CRL, Hart MP.   +4 more
europepmc   +1 more source