Results 191 to 200 of about 132,111 (275)

A century of theories of balancing selection

Biological Reviews, Volume 101, Issue 2, Page 804-825, April 2026.
ABSTRACT Traits that affect organismal fitness are often highly genetically variable. This genetic variation is vital for populations to adapt to their environments, but it is also surprising given that nature – after all – ‘selects’ the best genotypes at the expense of those that fall short.
Filip Ruzicka, Martyna K. Zwoinska, Debora Goedert, Hanna Kokko, Xiang‐Yi Li Richter, Iain R. Moodie, Sofie Nilén, Colin Olito, Erik I. Svensson, Peter Czuppon, Tim Connallon   +10 more
wiley   +1 more source

Enzymes of physiological amyloidogenesis control pathological amyloid toxicity. [PDF]

Life Sci Alliance
Bokros M, Grunfeld A, Balukoff NC, Bouviere J, Beurel E, Lee S.   +5 more
europepmc   +1 more source

Integration of epigenetics into ecotoxicology: insights and fundamental research needs

Biological Reviews, Volume 101, Issue 2, Page 826-847, April 2026.
ABSTRACT Epigenetics refers to heritable changes in genome function that occur without direct alterations to the DNA sequence. A multitude of environmental contaminants can influence the epigenetic marks of a genome. Changes of epigenetic marks including DNA methylation, histone modifications, and non‐coding RNAs can induce alterations at the gene ...
Albano Pinto, Jana Asselman, Patrícia Pereira, Joana Luísa Pereira   +3 more
wiley   +1 more source

GLA-3 mediates the heat shock response in Caenorhabditis elegans germ cells: A key role for the tristetraprolin (TTP) family. [PDF]

PLoS One
Salinas LS, Dámazo-Hernández ÁA, Cristino-Miranda AM, Zurita-León M, Morales-Oliva E, Láscarez-Lagunas LI, Navarro RE.   +6 more
europepmc   +1 more source

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel, Manuel J. Verganista, Nuno R. Candeias   +2 more
wiley   +1 more source

A scaffold attachment factor PHM-2 regulates synaptic transmission through SLO-2 potassium channel in C. elegans. [PDF]

PLoS Genet
Niu L, Murugasen K, Hanggodo S, Ferdousy S, Zhu L, Chen B.   +5 more
europepmc   +1 more source

Developing a Robust Multiround HCR-FISH Method Modified for Caenorhabditis elegans. [PDF]

Genes Cells
Yang X, Zeng J, Chen CK, Iino Y, Toyoshima Y.   +4 more
europepmc   +1 more source

The <i>Caenorhabditis</i> Gli protein TRA-1 makes a transcriptional activator that promotes spermatogenesis. [PDF]

iScience
Shen Y, Lin SY, Guo Y, Imtiaz J, Corley K, Ellis RE.   +5 more
europepmc   +1 more source

The Caenorhabditis Genetics Center Curated Special Collections: a guide to protein degradation systems. [PDF]

Genetics
Ward JD, Reiner DJ, Daul AL, Rougvie AE.
europepmc   +1 more source

Cell-intrinsic mTOR/LET-363 influences morphological aging of the ALM touch receptor neuron in Caenorhabditis elegans. [PDF]

PLoS One
Whitley SC, Zhong R, Baumberger S, Richardson CE.   +3 more
europepmc   +1 more source