Results 221 to 230 of about 136,487 (292)

Lifespan‐Extending Endogenous Metabolites

Aging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source

A Coffin-Siris syndrome-associated mutation modeled in Caenorhabditis elegans affects multiple developmental processes. [PDF]

G3 (Bethesda)
Baccas M, Liu J.
europepmc   +1 more source

Host Oxidative Response Capacity Determines Longevity Outcomes of Microbial Interventions

Aging Cell, Volume 25, Issue 2, February 2026.
Genetic variation determines whether microbial interactions extend or shorten host lifespan via redox homeostasis. This discovery highlights the critical role of host genetics in shaping microbiota‐driven aging, offering a new framework for precision microbiome interventions tailored to individual needs for promoting longevity.
Xusheng Hao, Rongwei Yuan, Yafei Guo, Guanyu Chen, Yongqing Guo, Limeng Liu, Fei Lu, Yang Bai, Ye Tian   +8 more
wiley   +1 more source

Loss of E3 ligase HvST1 function substantially increases distal crossover frequency

New Phytologist, Volume 249, Issue 3, Page 1325-1341, February 2026.
Summary This study characterizes the function of a grass‐specific E3 ubiquitin ligase, HvST1, in regulating synapsis and crossover (CO) formation during meiosis in barley (Hordeum vulgare). In large‐genome cereals, COs are predominantly restricted to distal chromosomal regions, limiting genetic recombination and breeding flexibility.
Jamie Neil Orr, Sybille Ursula Mittmann, Luke Ramsay, Dominika Lewandowska, Abdellah Barakate, Malcolm Macaulay, Nicola McCallum, Robbie Waugh, Isabelle Colas   +8 more
wiley   +1 more source

Defining the necessity of the lipoic acid synthase <i>lias-1</i> in <i>Caenorhabditis elegans</i>. [PDF]

MicroPubl Biol
Parker LB, Murray P, Kropp PA.
europepmc   +1 more source

Identifying regulators of associative learning using a protein-labelling approach in Caenorhabditis elegans. [PDF]

Elife
Rahmani A, McMillen A, Allen E, Ansaar R, Green R, Johnson ME, Poljak A, Chew YL.   +7 more
europepmc   +1 more source

Effects of Royal Jelly Freshness and Concentration on Lifespan, Growth, Motility and Reproduction in <i>Caenorhabditis elegans</i>. [PDF]

Foods
Zhang C, Deng Y, Luo Z, Liu S, Tao W, Zhang Y, Li H, Wu F.   +7 more
europepmc   +1 more source

Correction to "Identification of a G Protein-Coupled Receptor for Buccalin-Type Peptides in the Mollusk <i>Aplysia</i>: Evolutionary Insights into Neuropeptide Signaling". [PDF]

ACS Omega
Xu JP, Ding XY, Jin QC, Zhang YL, Chang JH, Jiang HM, Li YD, Fu P, Zhang YC, Liu CP, Mao RT, Liu CY, Li F, Wu SQ, Cropper EC, Zhang G, Jing J.   +16 more
europepmc   +1 more source

Orsay virus variants isolated from wild <i>Caenorhabditis elegans</i> nematodes, France. [PDF]

Microbiol Resour Announc
Fujii C, Vernon S, Félix M-A, Wang D.
europepmc   +1 more source

Parallel Evolution of X Chromosome-Specific Structural Maintenance of Chromosomes Complexes in Two Nematode Lineages. [PDF]

Mol Biol Evol
Aharonoff A, Kim J, Washington A, Ercan S.   +3 more
europepmc   +1 more source