Results 21 to 30 of about 132,111 (275)
Genetic analysis suggests a surface of PAT-4 (ILK) that interacts with UNC-112 (kindlin)
G3: Genes, Genomes, Genetics, 2022 Integrin plays a crucial role in the attachment of cells to the extracellular matrix. Integrin recruits many proteins intracellularly, including a 4-protein complex (kindlin, ILK, PINCH, and parvin).
Hiroshi Qadota +6 more
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Marine Drugs, 2021 With the widespread occurrence of aquaculture diseases and the broad application of antibiotics, drug-resistant pathogens have increasingly affected aquatic animals’ health.
Ying-Xiu Li +7 more
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Caenorhabditis elegans sperm membrane protein interactome [PDF]
Biology of Reproduction, 2018 The interaction and organization of proteins in the sperm membrane are important for all aspects of sperm function. We have determined the interactions between 12 known mutationally defined and cloned sperm membrane proteins in a model system for reproduction, the nematode Caenorhabditis elegans.
Marcello, Matthew R +2 more
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Comparative functional analysis of the Caenorhabditis elegans and Drosophila melanogaster proteomes. [PDF]
PLoS Biology, 2009 The nematode Caenorhabditis elegans is a popular model system in genetics, not least because a majority of human disease genes are conserved in C. elegans.
Sabine P Schrimpf +12 more
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The astacin protein family inCaenorhabditis elegans [PDF]
European Journal of Biochemistry, 2003 In the nematodeCaenorhabditis elegans, 40 genes code for astacin‐like proteins (nematode astacins, NAS). The astacins are metalloproteases present in bacteria, invertebrates and vertebrates and serve a variety of physiological functions like digestion, hatching, peptide processing, morphogenesis and pattern formation.
Moehrlen, F., Hutter, H., Zwilling, R.
openaire +3 more sources
BMC Genomics, 2021 Background F-box proteins represent a diverse class of adaptor proteins of the ubiquitin-proteasome system (UPS) that play critical roles in the cell cycle, signal transduction, and immune response by removing or modifying cellular regulators.
Ailan Wang, Wei Chen, Shiheng Tao
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American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023 Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei +4 more
wiley +1 more source
Curcumin reduced fat accumulation in Caenorhabditis elegans
Current Research in Food Science, 2021 Curcumin, the primary bioactive substance in turmeric, is known to be associated with weight loss. In this study, we employed Caenorhabditis elegans, a well-established in vivo nematode model to explore the role of curcumin in regulating lipid metabolism.
Yiren Yue +3 more
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Scientific Reports, 2021 Alzheimer disease (AD) is a neurodegenerative disorder with an –as of yet– unclear etiology and pathogenesis. Research to unveil disease processes underlying AD often relies on the use of neurodegenerative disease model organisms, such as Caenorhabditis ...
Avgi E. Apostolakou +4 more
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Ecotoxicology and Environmental Safety, 2021 The aim of this study was to identify Gα proteins mediating function of neuronal G protein-coupled receptors (GPCRs) in controlling the response to polystyrene nanoparticles (PS-NPs).
Yunhan Yang, Qiuli Wu, Dayong Wang
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