Results 121 to 130 of about 6,761 (193)

Identification of modulators of the ALT pathway through a native FISH-based optical screen

Cell Reports
Summary: A significant portion of human cancers utilize a recombination-based pathway, alternative lengthening of telomeres (ALT), to extend telomeres. To gain further insights into this pathway, we developed a high-throughput imaging-based screen named ...
Benura Azeroglu, Simran Khurana, Shih-Chun Wang, Gianna M. Tricola, Shalu Sharma, Camille Jubelin, Ylenia Cortolezzis, Gianluca Pegoraro, Kyle M. Miller, Travis H. Stracker, Eros Lazzerini Denchi   +10 more
doaj   +1 more source

Rational engineering of microRNA-regulated viruses for cancer gene therapy [PDF]

, 2013
MicroRNAs (miRNAs) are small noncoding RNA molecules that have important regulatory roles in a wide range of biological processes. miRNAs are often expressed in a tissue- and/or differentiation state-specific patterns, and it is estimated that miRNAs can
Ylösmäki, Erkko
core  

Disordered regions and folded modules in CAF-1 promote histone deposition in Schizosaccharomyces pombe

eLife
Genome and epigenome integrity in eukaryotes depends on the proper coupling of histone deposition with DNA synthesis. This process relies on the evolutionary conserved histone chaperone CAF-1 for which the links between structure and functions are still ...
Fouad Ouasti, Maxime Audin, Karine Fréon, Jean-Pierre Quivy, Mehdi Tachekort, Elizabeth Cesard, Aurélien Thureau, Virginie Ropars, Paloma Fernández Varela, Gwenaelle Moal, Ibrahim Soumana Adamou, Aleksandra Uryga, Pierre Legrand, Jessica Andreani, Raphaël Guerois, Geneviève Almouzni, Sarah Lambert, Francoise Ochsenbein   +17 more
doaj   +1 more source

Estudio de las células sanguíneas como fuente de marcadores transcriptómicos de utilidad para la investigación de la obesidad y sus complicaciones [PDF]

Introducció: La dieta és un determinant fonamental del nostre estat de salut/malaltia, i és un dels principals factors que contribueixen al desenvolupament de l’obesitat.
Departament de Biologia Fonamental i Ciències de la Salut, Reynés Miralles, Bàrbara   +1 more
core  

Hot Off the Bench—Late Breaking Abstracts Society for Investigative Dermatology Annual Meeting May 5–9, 1999 [PDF]

, 1999
Ajuntament de Barcelona
core   +2 more sources

CCR4-associated factor CAF1I promotes plant growth and ectomycorrhizal formation in Populus tomentosa. [PDF]

Mycorrhiza
Liu Y, Li C, Yang Z, Matsushita N, Lian C.   +4 more
europepmc   +1 more source

A de novo H3.2K9me2 deposition pathway establishes heterochromatin for suppressing transposon mobilization during fly somatic development. [PDF]

Nucleic Acids Res
Luo YN, Deng Y, Liang Y, Wu W, Wu W, Wang L.   +5 more
europepmc   +1 more source

Retrotransposons are the major contributors to the expansion of the Drosophila ananassae Muller F element [PDF]

, 2017
et al,, Mardis, Elaine R
core   +1 more source

HP1β recruits RING1A to ubiquitinate histone H2A for BRCA1-mediated resection of double-stand breaks. [PDF]

iScience
Charaka V, Pandita RK, Tsai CL, Wang X, Chakraborty S, Ramos KS, Nandi S, Leonard F, Singh V, Sarkar PS, Hunt CR, Tainer JA, Das C, Pandita TK.   +13 more
europepmc   +1 more source

ZEB1, a novel junctional adhesion molecule A regulator, impacts sensitivity of pancreatic cancer-associated fibroblasts to reovirus. [PDF]

Mol Ther Oncol
Dam N, Harryvan TJ, Dang H, Ioannidis G, Schmierer B, Hawinkels LJAC, Kemp V.   +6 more
europepmc   +1 more source