Tumor integrin targeted theranostic iron oxide nanoparticles for delivery of caffeic acid phenethyl ester: preparation, characterization, and anti-myeloma activities. [PDF]
Smith B +8 more
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Caffeic acid phenethyl ester inhibits neuro-inflammation and oxidative stress following spinal cord injury by mitigating mitochondrial dysfunction via the SIRT1/PGC1α/DRP1 signaling pathway. [PDF]
Zhang Y +5 more
europepmc +1 more source
The Gehan test identifies life-extending compounds overlooked by the log-rank test in the NIA Interventions Testing Program: Metformin, Enalapril, caffeic acid phenethyl ester, green tea extract, and 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride. [PDF]
Jiang N +4 more
europepmc +1 more source
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Interaction between caffeic acid/caffeic acid phenethyl ester and micellar casein
Food Chemistry, 2021Caffeic acid (CA) and caffeic acid phenethyl ester (CAPE) are bioactive molecules with poor solubility. We investigated the interaction between CA/CAPE and micellar casein (MC), and the physico-chemical and antioxidant properties of the complexes. Fluorescence spectroscopy analysis showed that both CA and CAPE formed complexes with MC via hydrophobic ...
Juanjuan Qin, Min Yang, Yucheng Wang
exaly +3 more sources
Enzymatic synthesis of caffeic acid phenethyl ester
Journal of the Taiwan Institute of Chemical Engineers, 2008Caffeic acid phenethyl ester was succcssfully synthesized from caffeic acid and phenethyl alcohol catalyzed by Novozym 435. Caffeic acid was found to yield much higher conversion in non-polar solvents than in polar ones, albeit its low solubility in non polar solvents.
Arief Widjaja, Yi-Hsu Ju
exaly +3 more sources
Caffeic Acid Phenethyl Ester Ameliorated Ototoxicity Induced by Cisplatin in Rats
Journal of Chemotherapy, 2004Caffeic acid phenethyl ester (CAPE), an active component of propolis, exhibits antioxidant properties. This experimental study was designed to determine the effect of CAPE on ototoxicity induced with cisplatin. Twenty-four adult Wistar albino rats were divided into four groups: cisplatin (n=6), saline (n=6), CAPE (n=6), and cisplatin plus CAPE (n=6 ...
Ahmet Kızılay +2 more
exaly +3 more sources
Recent progresses in the pharmacological activities of caffeic acid phenethyl ester
Naunyn-Schmiedeberg's Archives of Pharmacology, 2021The past decades have seen a growing interest in natural products. Caffeic acid phenethyl ester (CAPE), a flavonoid isolated from honeybee propolis, has shown multiple pharmacological potentials, including anti-cancer, anti-inflammatory, antioxidant, antibacterial, antifungal, and protective effects on nervous systems and multiple organs, since it was ...
Lili Lv +4 more
openaire +2 more sources
Effects of Caffeic Acid Phenethyl Ester on Pancreatitis in Rats
Journal of Surgical Research, 2008This study investigated the effect of caffeic acid phenethyl ester (CAPE) on acute necrotizing pancreatitis (ANP) induced by glycodeoxycholic acid in rats. CAPE, an active component of honeybee propolis, has previously been determined to have antioxidant, anti-inflammatory, antiviral, and anticancer activities.Forty-eight rats were divided into four ...
ERDOĞAN, SELİM +7 more
openaire +3 more sources
The effect of caffeic acid phenethyl ester (CAPE) on tympanosclerosis
International Journal of Pediatric Otorhinolaryngology, 2017To investigate the effects of caffeic acid phenethyl ester (CAPE) on tympanosclerosis.Thirty-two male Sprague Dawley rats were separated into 4 groups as CAPE (n = 10), alcohol (n = 10), control (n = 8) and normal (n = 4) groups. All tympanic membranes except normal group were myringotomised and type 3 Streptococcus pneumoniae strains was injected into
İbrahim, Ağrı +8 more
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Caffeic acid phenethyl ester (CAPE) is a bioactive polyphenolic compound obtained from propolis extract. Although it has a broad therapeutic potential, the bioavailability of CAPE is limited, due to reduced solubility and poor plasmatic stability. Efforts to reduce these pharmacokinetic drawbacks resulted in the synthesis of caffeic acid phenethyl ...
E. Manuela P.J. Garrido +5 more
openaire +2 more sources

