Tumor integrin targeted theranostic iron oxide nanoparticles for delivery of caffeic acid phenethyl ester: preparation, characterization, and anti-myeloma activities. [PDF]
Smith B +8 more
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The Gehan test identifies life-extending compounds overlooked by the log-rank test in the NIA Interventions Testing Program: Metformin, Enalapril, caffeic acid phenethyl ester, green tea extract, and 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride. [PDF]
Jiang N +4 more
europepmc +1 more source
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Interaction between caffeic acid/caffeic acid phenethyl ester and micellar casein
Food Chemistry, 2021Caffeic acid (CA) and caffeic acid phenethyl ester (CAPE) are bioactive molecules with poor solubility. We investigated the interaction between CA/CAPE and micellar casein (MC), and the physico-chemical and antioxidant properties of the complexes ...
Min Yang, Yucheng Wang
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Recent progresses in the pharmacological activities of caffeic acid phenethyl ester
Naunyn-Schmiedeberg's Archives of Pharmacology, 2021The past decades have seen a growing interest in natural products. Caffeic acid phenethyl ester (CAPE), a flavonoid isolated from honeybee propolis, has shown multiple pharmacological potentials, including anti-cancer, anti-inflammatory, antioxidant, antibacterial, antifungal, and protective effects on nervous systems and multiple organs, since it was ...
L. Lv +4 more
semanticscholar +3 more sources
Caffeic acid phenethyl ester as a lipoxygenase inhibitor with antioxidant properties [PDF]
Caffeic acid phenethyl ester, an active component of propolis extract, inhibits 5‐lipoxygenase in the micromolar concentration range. The inhibition is of an uncompetitive type, i.e. the inhibitor binds to the enzyme‐substrate complex but not to the free enzyme. Caffeic acid phenethyl ester also exhibits antioxidant properties. At a concentration of 10
Natalia Sumbatyan, S D Varfolomeev
exaly +3 more sources
Therapeutic efficacy of caffeic acid phenethyl ester in cancer therapy: An updated review
Chemical Biology and Drug Design, 2023Nowadays, there is a lot of public and scientific interest in using phytochemicals to treat human ailments. Existing cancer medicines still run across obstacles, despite significant advancements in the field.
P. Pandey +3 more
semanticscholar +1 more source
Therapeutic Potential of Caffeic Acid Phenethyl Ester (CAPE) in Diabetes
Current Medicinal Chemistry, 2019Diabetes mellitus is a complex metabolic disease characterized by high blood sugar levels. Different pathogenic processes are involved in the etiology of the disease. Indeed, chronic diabetes hyperglycemia is often associated with severe long-term complications including cardiovascular symptoms, retinopathy, nephropathy, and neuropathy.
Loredana Salerno +2 more
exaly +3 more sources
Caffeic Acid Phenethyl Ester: A Potential Therapeutic Cancer Agent?
Current Medicinal Chemistry, 2023BACKGROUND Propolis and its major phenolic compound, caffeic acid phenethyl ester (CAPE), have garnered considerable scientific interest due to their anti-inflammatory properties and potential therapeutic applications.
Geir Bjørklund +9 more
semanticscholar +1 more source
Effects of Caffeic Acid Phenethyl Ester on Pancreatitis in Rats
Journal of Surgical Research, 2008This study investigated the effect of caffeic acid phenethyl ester (CAPE) on acute necrotizing pancreatitis (ANP) induced by glycodeoxycholic acid in rats. CAPE, an active component of honeybee propolis, has previously been determined to have antioxidant, anti-inflammatory, antiviral, and anticancer activities.Forty-eight rats were divided into four ...
ATEŞ, BURHAN +7 more
openaire +3 more sources
Enzymatic synthesis of caffeic acid phenethyl ester
Journal of the Taiwan Institute of Chemical Engineers, 2008Caffeic acid phenethyl ester was succcssfully synthesized from caffeic acid and phenethyl alcohol catalyzed by Novozym 435. Caffeic acid was found to yield much higher conversion in non-polar solvents than in polar ones, albeit its low solubility in non polar solvents.
Arief Widjaja, Yi-Hsu Ju
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