Results 141 to 150 of about 3,475 (164)
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Suppression of cell transformation and induction of apoptosis by caffeic acid phenethyl ester
Molecular Carcinogenesis, 2001AbstractCaffeic acid phenethyl ester (CAPE), which is derived from the propolis of honeybee hives, has been shown to block tumor promotion and to have toxic effects on several cancer cells. The mechanism of the anti–tumor promotion activity of CAPE is unclear, however.
M, Nomura +4 more
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The protective role of caffeic acid phenethyl ester against streptomycin ototoxicity
American Journal of Otolaryngology, 2013The aim of this experimental study was to investigate the efficacy of caffeic acid phenethyl ester (CAPE) in the prevention of streptomycin-induced ototoxicity.Thirty-two adult Wistar albino rats were divided into 4 groups: control (n = 8), streptomycin (n = 8), CAPE (n = 8), and streptomycin + CAPE (n = 8).
Salih, Bakır +8 more
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Caffeic acid phenethyl ester as an adjuvant therapy for advanced prostate cancer
Medical Hypotheses, 2013Prostate cancer is the second most frequently diagnosed cancer of men. Androgen ablation therapy is the primary treatment for metastatic prostate cancer. However, the majority of prostate cancer patients receiving the androgen ablation therapy will ultimately develop recurrent castration-resistant tumors within 3 years. Chemotherapy shows little effect
Chun-Chieh, Liu +3 more
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Radio-Modulatory Potential of Caffeic Acid Phenethyl Ester: A Therapeutic Perspective
Anti-Cancer Agents in Medicinal Chemistry, 2018Background: Use of natural agents is an upcoming area of research in cancer biology. Caffeic acid phenethyl ester (CAPE) has received great attention because of its therapeutic potential in various conditions including cancer. It is an active/abundant component of propolis, a honey bee hive product produced by bees using their enzyme-rich digestive ...
Km, Anjaly, Ashu B, Tiku
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Caffeic acid phenethyl ester prevents intestinal reperfusion injury in rats
Journal of Pediatric Surgery, 1999Ischemia-reperfusion injury is encountered frequently in conditions that diminish intestinal blood flow. Caffeic acid phenethyl ester (CAPE), which is a specific component of the honeybee hive product propolis, exhibits potential antioxidant properties.
U, Koltuksuz +8 more
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The effect of caffeic acid phenethyl ester on facial nerve regeneration
Acta Oto-LaryngologicaCaffeic acid phenethyl ester (CAPE), an active component of honey bee propolis, has been demonstrated in animal models and studies to have anti-inflammatory, antioxidant, immunomodulatory, neuroprotective, and cytoprotective properties.We investigated the efficacy of CAPE, which we believe may be therapeutically useful in facial nerve restoration due ...
Veysel Alparslan Gölcük +1 more
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Cancer Chemotherapy and Pharmacology, 2005
To investigate antiproliferative and radiosensitizing effects of caffeic acid phenethyl ester (CAPE) on medulloblastoma (MB) Daoy cells.Daoy cells were treated with CAPE in different concentrations and assessed for cell viability, apoptosis, cell cycles, cyclin B1 expressions, radiosensitization and chemosensitization. Human astroglia SVGp12 cells were
Yi-Hsien, Lin +5 more
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To investigate antiproliferative and radiosensitizing effects of caffeic acid phenethyl ester (CAPE) on medulloblastoma (MB) Daoy cells.Daoy cells were treated with CAPE in different concentrations and assessed for cell viability, apoptosis, cell cycles, cyclin B1 expressions, radiosensitization and chemosensitization. Human astroglia SVGp12 cells were
Yi-Hsien, Lin +5 more
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Antitumor effect of propolis : a comparison with caffeic acid and caffeic acid phenethyl ester
1999The antitumor effect of a water soluble derivative of propolis (WSDP) caffeic acid (CA) and caffeic acid phenethyl ester (CAPE), components of natural propolis, were investigated. The oral administration of these compounds (50 mg/kg or 150 mg/kg) given before or after tumor cell inoculation supressed tumor growth of a weakly immunogeneic mammary ...
Brbot-Šaranović, Ana +6 more
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Anti-COVID-19 Potential of Withaferin-A and Caffeic Acid Phenethyl Ester
Current Topics in Medicinal ChemistryBackground: The recent COVID-19 (coronavirus disease 2019) pandemic triggered research on the development of new vaccines/drugs, repurposing of clinically approved drugs, and assessment of natural anti-COVID-19 compounds. Based on the gender difference in the severity of the disease, such as a higher number of men hospitalized and in intense care ...
Vipul, Kumar +8 more
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