Results 161 to 170 of about 7,555 (199)

Caffeic acid phenethyl ester induces radiosensitization via inhibition of DNA damage repair in androgen‐independent prostate cancer cells

Environmental Toxicology, 2022
In the present study, we evaluated the radiomodulatory potential of caffeic acid phenethyl ester (CAPE), an active component of traditional herbal medicine propolis.
Km Anjaly, A. B. Tiku
semanticscholar   +1 more source

Caffeic acid phenethyl ester: An effective antiviral agent against porcine reproductive and Respiratory Syndrome Virus.

Antiviral Research
Porcine Reproductive and Respiratory Syndrome (PRRS) presents a formidable viral challenge in swine husbandry. Confronting the constraints of existing veterinary pharmaceuticals and vaccines, this investigation centers on Caffeic Acid Phenethyl Ester ...
Zhanding Cui, Jing Zhang, Jinlong Wang, Jinlong Liu, P. Sun, Jiaoyang Li, Guoxiu Li, Ying Sun, Juanbin Ying, Kun Li, Zhixun Zhao, Hong Yuan, Xingwen Bai, Xueqing Ma, Pinghua Li, Yuanfang Fu, H. Bao, Dong Li, Qiang Zhang, Zai-xin Liu, Yimei Cao, Zengjun Lu   +21 more
semanticscholar   +1 more source

Effect of caffeic acid phenethyl ester on corneal neovascularization in rats

Current Eye Research, 2001
Caffeic acid phenethyl ester (CAPE), a biologically active component of propolis from honeybee hives, has potent antiinflammatory and antioxidant properties. We aimed to evaluate the ability of topically applied CAPE in comparison with known steroidal (dexamethasone sodium phosphate) and nonsteroidal (indomethacin) topical agents to reduce corneal ...
Y, Totan, E, Aydin, O, Cekiç, M, Cihan Dağloğlu, M, Borazan, K, Dağlioğlu, A, Gültek   +6 more
openaire   +3 more sources

Caffeic acid phenethyl ester ameliorates colistin‐induced nephrotoxicity in rats via modulation of FOXO1/Nrf2/Sirt1 axis

Clinical and Experimental Pharmacology and Physiology
Colistin (Cst) is one of the antimicrobial peptides and is reserved for use against multi‐drug‐resistant Gram‐negative bacteria. However, the clinical value of Cst is limited by its nephrotoxic adverse effects.
M. Nasrullah, Thikryat Neamtalllah, Mohannad Alshibani, A. Bagalagel, A. Noor, Hussain T Bakhsh, Ashraf B. Abdel-Naim   +6 more
semanticscholar   +1 more source

Caffeic acid phenethyl ester targets ubiquitin-specific protease 8 and synergizes with cisplatin in endometrioid ovarian carcinoma cells.

Biochemical Pharmacology, 2022
Deubiquitinases (DUBs) mediate the removal of ubiquitin from diverse proteins that participate in the regulation of cell survival, DNA damage repair, apoptosis and drug resistance.
D. Colombo, L. Gatti, Linda Sjöstrand, N. Carenini, Matteo Costantino, E. Corna, N. Arrighetti, M. Zuccolo, M. de Cesare, S. Linder, Padraig D'arcy, P. Perego   +11 more
semanticscholar   +1 more source

The effects of caffeic acid phenethyl ester on retina in a diabetic rat model

Cutaneous and Ocular Toxicology, 2021
We aimed to investigate the effect of caffeic acid phenethyl ester (CAPE) on retinal apoptosis and oxidative stress parameters in streptozotocin (STZ) induced diabetic rat model.This study included 3 groups; control, STZ, and STZ + CAPE. The rats in STZ, and STZ + CAPE groups were injected with STZ (35 mg/kg, i.p.) for induction of diabetes. In the STZ 
Alparslan Şahin, Savaş Kaya, Mukadder Baylan   +2 more
openaire   +2 more sources

Antioxidant Capacity of Caffeic Acid Phenethyl Ester in Scavenging Free Radicals by a Computational Insight

Polycyclic aromatic compounds (Print), 2022
The free radicals, due to having a single free electron, are highly reactive in the body and cause irreversible damage to the macromolecules of living organisms.
K. Hachem, D. Bokov, L. Mahdavian
semanticscholar   +1 more source

Effect of caffeic acid phenethyl ester on cartilage in experimental osteoarthritis

Rheumatology International, 2002
Activation of nuclear factor kappa B (NF-kappaBeta) in synovial cells is seen in RA and OA patients. Caffeic acid phenethyl ester (CAPE) is a specific and potent inhibitor of NF-kappaBeta. We aimed to determine the in vivo effects of intra-articular injections of CAPE on cartilage in an experimental rabbit osteoarthritis (OA) model.
Nurzat, Elmali, Irfan, Ayan, Yusuf, Türköz, Bülent, Mizrak, Burak, Germen, Arslan, Bora   +5 more
openaire   +2 more sources

Effects of Caffeic Acid Phenethyl Ester (CAPE) on Hepatopulmonary Syndrome

Inflammation, 2010
The aim of this study was to investigate the effects of caffeic acid phenethyl ester (CAPE) on inflammatory and related histopathological changes in the lung and liver in experimental hepatopulmonary syndrome (HPS) model. Forty Sprague Dawley rats were used in this study. The animals were divided into four groups of ten rats each.
Ahmet, Tekin, Serdar, Türkyılmaz, Tevfik, Küçükkartallar, Murat, Cakır, Hüseyin, Yılmaz, Hasan, Esen, Burhan, Ateş, Ilhan, Ciftci, Adil, Kartal   +8 more
openaire   +2 more sources

Suppression of cell transformation and induction of apoptosis by caffeic acid phenethyl ester

Molecular Carcinogenesis, 2001
AbstractCaffeic acid phenethyl ester (CAPE), which is derived from the propolis of honeybee hives, has been shown to block tumor promotion and to have toxic effects on several cancer cells. The mechanism of the anti–tumor promotion activity of CAPE is unclear, however.
M, Nomura, A, Kaji, W, Ma, K, Miyamoto, Z, Dong   +4 more
openaire   +2 more sources