Caffeic acid phenethyl ester inhibits neuro-inflammation and oxidative stress following spinal cord injury by mitigating mitochondrial dysfunction via the SIRT1/PGC1α/DRP1 signaling pathway. [PDF]
J Transl MedZhang Y +5 more
europepmc +1 more source
The Gehan test identifies life-extending compounds overlooked by the log-rank test in the NIA Interventions Testing Program: Metformin, Enalapril, caffeic acid phenethyl ester, green tea extract, and 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride. [PDF]
GeroscienceJiang N +4 more
europepmc +1 more source
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Interaction between caffeic acid/caffeic acid phenethyl ester and micellar casein
Food Chemistry, 2021Caffeic acid (CA) and caffeic acid phenethyl ester (CAPE) are bioactive molecules with poor solubility. We investigated the interaction between CA/CAPE and micellar casein (MC), and the physico-chemical and antioxidant properties of the complexes. Fluorescence spectroscopy analysis showed that both CA and CAPE formed complexes with MC via hydrophobic ...
Min Yang, Yucheng Wang
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Enzymatic synthesis of caffeic acid phenethyl ester
Journal of the Taiwan Institute of Chemical Engineers, 2008Caffeic acid phenethyl ester was succcssfully synthesized from caffeic acid and phenethyl alcohol catalyzed by Novozym 435. Caffeic acid was found to yield much higher conversion in non-polar solvents than in polar ones, albeit its low solubility in non polar solvents.
Arief Widjaja
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Bee Propolis (Caffeic Acid Phenethyl Ester) Against Cancer
2021Caffeic acid phenethyl ester (CAPE) is the vital natural phenolic chemical composite present in a variety of plants which is also abundantly present in the honeybee hives as propolis. It is the combination of caffeic acid and phenethyl alcohol. There are many studies reported the pharmacological and physiological activities of CAPE in a variety of in ...
Maqsood Ur Rehman +3 more
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Caffeic acid phenethyl ester (CAPE) is a bioactive polyphenolic compound obtained from propolis extract. Although it has a broad therapeutic potential, the bioavailability of CAPE is limited, due to reduced solubility and poor plasmatic stability. Efforts to reduce these pharmacokinetic drawbacks resulted in the synthesis of caffeic acid phenethyl ...
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Caffeic acid phenethyl ester as a lipoxygenase inhibitor with antioxidant properties [PDF]
FEBS Letters, 1993 Caffeic acid phenethyl ester, an active component of propolis extract, inhibits 5‐lipoxygenase in the micromolar concentration range. The inhibition is of an uncompetitive type, i.e. the inhibitor binds to the enzyme‐substrate complex but not to the free enzyme. Caffeic acid phenethyl ester also exhibits antioxidant properties. At a concentration of 10
Galina Sud'ina, Nataliya V Sumbatyan
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Effects of Caffeic Acid Phenethyl Ester on Pancreatitis in Rats
Journal of Surgical Research, 2008This study investigated the effect of caffeic acid phenethyl ester (CAPE) on acute necrotizing pancreatitis (ANP) induced by glycodeoxycholic acid in rats. CAPE, an active component of honeybee propolis, has previously been determined to have antioxidant, anti-inflammatory, antiviral, and anticancer activities.Forty-eight rats were divided into four ...
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