Results 171 to 180 of about 7,555 (199)

The protective role of caffeic acid phenethyl ester against streptomycin ototoxicity

American Journal of Otolaryngology, 2013
The aim of this experimental study was to investigate the efficacy of caffeic acid phenethyl ester (CAPE) in the prevention of streptomycin-induced ototoxicity.Thirty-two adult Wistar albino rats were divided into 4 groups: control (n = 8), streptomycin (n = 8), CAPE (n = 8), and streptomycin + CAPE (n = 8).
Salih, Bakır, Musa, Özbay, Ramazan, Gün, Ediz, Yorgancılar, Vefa, Kınış, Ayşenur, Keleş, Abdurrahman, Abakay, Osman, Gökalp, İsmail, Topçu   +8 more
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Caffeic acid phenethyl ester as an adjuvant therapy for advanced prostate cancer

Medical Hypotheses, 2013
Prostate cancer is the second most frequently diagnosed cancer of men. Androgen ablation therapy is the primary treatment for metastatic prostate cancer. However, the majority of prostate cancer patients receiving the androgen ablation therapy will ultimately develop recurrent castration-resistant tumors within 3 years. Chemotherapy shows little effect
Chun-Chieh, Liu, Jong-Ming, Hsu, Li-Kuo, Kuo, Chih-Pin, Chuu   +3 more
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Radio-Modulatory Potential of Caffeic Acid Phenethyl Ester: A Therapeutic Perspective

Anti-Cancer Agents in Medicinal Chemistry, 2018
Background: Use of natural agents is an upcoming area of research in cancer biology. Caffeic acid phenethyl ester (CAPE) has received great attention because of its therapeutic potential in various conditions including cancer. It is an active/abundant component of propolis, a honey bee hive product produced by bees using their enzyme-rich digestive ...
Km, Anjaly, Ashu B, Tiku
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Caffeic acid phenethyl ester prevents intestinal reperfusion injury in rats

Journal of Pediatric Surgery, 1999
Ischemia-reperfusion injury is encountered frequently in conditions that diminish intestinal blood flow. Caffeic acid phenethyl ester (CAPE), which is a specific component of the honeybee hive product propolis, exhibits potential antioxidant properties.
U, Koltuksuz, S, Ozen, E, Uz, M, Aydinç, A, Karaman, A, Gültek, O, Akyol, M H, Gürsoy, E, Aydin   +8 more
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The effect of caffeic acid phenethyl ester on facial nerve regeneration

Acta Oto-Laryngologica
Caffeic acid phenethyl ester (CAPE), an active component of honey bee propolis, has been demonstrated in animal models and studies to have anti-inflammatory, antioxidant, immunomodulatory, neuroprotective, and cytoprotective properties.We investigated the efficacy of CAPE, which we believe may be therapeutically useful in facial nerve restoration due ...
Veysel Alparslan Gölcük, Lütfü Şeneldir   +1 more
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Caffeic Acid Phenethyl Ester Ameliorated Ototoxicity Induced by Cisplatin in Rats

Journal of Chemotherapy, 2004
Caffeic acid phenethyl ester (CAPE), an active component of propolis, exhibits antioxidant properties. This experimental study was designed to determine the effect of CAPE on ototoxicity induced with cisplatin. Twenty-four adult Wistar albino rats were divided into four groups: cisplatin (n=6), saline (n=6), CAPE (n=6), and cisplatin plus CAPE (n=6 ...
A, Kizilay, M T, Kalcioglu, E, Ozerol, M, Iraz, M, Gulec, O, Akyol, O, Ozturan   +6 more
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Structural Basis for the Inhibition of AKR1B10 by Caffeic Acid Phenethyl Ester (CAPE)

ChemMedChem, 2014
AbstractCaffeic acid phenethyl ester (CAPE), the major bioactive component of honeybee propolis, is a potent selective inhibitor of aldo‐keto reductase family member 1B10 (AKR1B10), and a number of derivatives hold promise as potential anticancer agents. However, sequence homology between AKR1B10 and other members of the superfamily, including critical
Liping, Zhang, Hong, Zhang, Xuehua, Zheng, Yining, Zhao, Shangke, Chen, Yunyun, Chen, Renwei, Zhang, Qing, Li, Xiaopeng, Hu   +8 more
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Caffeic acid phenethyl ester attenuates indomethacin-induced gastric ulcer in rats

Naunyn-Schmiedeberg's Archives of Pharmacology, 2023
Thikryat A. Neamatallah
semanticscholar   +1 more source

Antitumor effect of propolis : a comparison with caffeic acid and caffeic acid phenethyl ester

1999
The antitumor effect of a water soluble derivative of propolis (WSDP) caffeic acid (CA) and caffeic acid phenethyl ester (CAPE), components of natural propolis, were investigated. The oral administration of these compounds (50 mg/kg or 150 mg/kg) given before or after tumor cell inoculation supressed tumor growth of a weakly immunogeneic mammary ...
Brbot-Šaranović, Ana, Horvat Knežević, Anica, Kocijan, Ivna, Oršolić, Nada, Bendelja, Krešo, Rabatić, Sabina, Bašić, Ivan   +6 more
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Caffeic acid phenethyl ester alleviated hypouricemia in hyperuricemic mice through inhibiting XOD and up-regulating OAT3.

Phytomedicine, 2022
T. Yong, Danling Liang, Shaodan Chen, Chun Xiao, Xiong Gao, Qingping Wu, Yizhen Xie, Long-hua Huang, Huiping Hu, Xiangmin Li, Yuancao Liu, Manjun Cai   +11 more
semanticscholar   +1 more source