Results 151 to 160 of about 7,555 (199)

The effect of caffeic acid phenethyl ester (CAPE) on tympanosclerosis

International Journal of Pediatric Otorhinolaryngology, 2017
To investigate the effects of caffeic acid phenethyl ester (CAPE) on tympanosclerosis.Thirty-two male Sprague Dawley rats were separated into 4 groups as CAPE (n = 10), alcohol (n = 10), control (n = 8) and normal (n = 4) groups. All tympanic membranes except normal group were myringotomised and type 3 Streptococcus pneumoniae strains was injected into
İbrahim, Ağrı, Arzu, Erdal Ağrı, Mehmet Eser, Sancaktar, Asude, Ünal, Erkan, Can, Mustafa, Bakırtaş, Fatih, Yılmaz, Mehmet Derya, Demirağ, Recep, Ünal   +8 more
openaire   +2 more sources

Microencapsulation of caffeic acid phenethyl ester and caffeic acid phenethyl amide by inclusion in hydroxypropyl-β-cyclodextrin

Food Chemistry, 2018
Caffeic acid phenethyl ester (CAPE) is a bioactive polyphenolic compound obtained from propolis extract. Although it has a broad therapeutic potential, the bioavailability of CAPE is limited, due to reduced solubility and poor plasmatic stability. Efforts to reduce these pharmacokinetic drawbacks resulted in the synthesis of caffeic acid phenethyl ...
E. Manuela P.J. Garrido, Ana S. Cerqueira, Daniel Chavarria, Tiago Silva, Fernanda Borges, Jorge M.P.J. Garrido   +5 more
openaire   +2 more sources

Effects of Caffeic Acid Phenethyl Ester (CAPE) on Sepsis in Rats

Inflammation, 2008
Sepsis is still a major cause of the high mortality rate in the intensive care unit. Many studies have been published about the severity of sepsis, but the cause of mortality in sepsis and multiorgan failure is still obscure. This study investigated the effects of caffeic acid phenethyl ester (CAPE) particularly on the inflammatory and related ...
Ahmet, Tekin, Tevfik, Küçükkartallar, Serdar, Türkyilmaz, Ayhan, Dinckan, Hasan, Esen, Burhan, Ateş, Hüseyin, Yilmaz, Adil, Kartal   +7 more
openaire   +3 more sources

Caffeic Acid Phenethyl Ester Is a Potential Therapeutic Agent for Oral Cancer [PDF]

International Journal of Molecular Sciences, 2015
Head and neck cancers, which affect 650,000 people and cause 350,000 deaths per year, is the sixth leading cancer by cancer incidence and eighth by cancer-related death worldwide. Oral cancer is the most common type of head and neck cancer. More than 90% of oral cancers are oral and oropharyngeal squamous cell carcinoma (OSCC).
Chuu Chih-Pin, Ching Yu Lin, Chi-Jung Chung   +2 more
exaly   +3 more sources

Caffeic Acid Phenethyl Ester (CAPE)

Shock, 2014
Excessive free radical production by immune cells has been linked to cell death and tissue injury during sepsis. Peroxynitrite is a short-lived oxidant and a potent inducer of cell death that has been identified in several pathological conditions. Caffeic acid phenethyl ester (CAPE) is an active component of honeybee products and exhibits antioxidant ...
Mustafa, Kassim, Marzida, Mansor, Tengku Ain, Kamalden, Ina Ismiarti, Shariffuddin, Mohd Shahnaz, Hasan, Gracie, Ong, Shamala Devi, Sekaran, Anwar, Suhaimi, Nazeh, Al-Abd, Kamaruddin Mohd, Yusoff   +9 more
openaire   +2 more sources

Yeast Metabolic Engineering for Biosynthesis of Caffeic Acid-Derived Phenethyl Ester and Phenethyl Amide

ACS Synthetic Biology, 2023
Caffeic acid (CA)-derived phenethyl ester (CAPE) and phenethyl amide (CAPA) are extensively investigated bioactive compounds with therapeutic applications such as antioxidant, anti-inflammatory, and anticarcinogenic properties. To construct microbial cell factories for production of CAPE or CAPA is a promising option given the limitation of natural ...
Zi-Chen Jia, Duo Liu, Hai-Di Ma, Yu-Hui Cui, Hui-Min Li, Xia Li, Ying-Jin Yuan   +6 more
openaire   +2 more sources

Co-delivery of quercetin and caffeic-acid phenethyl ester by polymeric nanoparticles for improved antitumor efficacy in colon cancer cells

Journal of Microencapsulation, 2021
Aim This study aimed to synthesise quercetin- caffeic-acid phenethyl ester (CAPE)-co-loaded poly(lactic-co-glycolic-acid) (PLGA) nanoparticles (QuCaNP) and investigate their anti-cancer activity on human colorectal carcinoma HT-29 cells.
R. D. Colpan, A. Erdemir
semanticscholar   +1 more source

Structure‐based identification of herbacetin and caffeic acid phenethyl ester as inhibitors of S‐adenosylmethionine‐dependent viral methyltransferase

FEBS Letters
Chikungunya (CHIKV) and dengue (DENV) viruses pose a public health risk and lack antiviral treatments. Structure‐based molecular docking of a natural MTase substrates library identified herbacetin (HC) and caffeic acid phenethyl ester (CAPE) as potential
Mandar Bhutkar, Amith Kumar, R. Rani, Vishakha Singh, Ankita Saha, Akashjyoti Pathak, Aditi Kothiala, Supreeti Mahajan, B. Waghmode, Shalja Verma, Ravi Kumar, R. Mudgal, Debabrata Sircar, Pravindra Kumar, S. Tomar   +14 more
semanticscholar   +1 more source

Effect of caffeic acid phenethyl ester on gastric acid secretion in vitro

European Journal of Pharmacology, 2005
Caffeic acid phenethyl ester (CAPE), one of the major components of propolis (honeybee resin), has demonstrated a wide spectrum of activities including suppression of eicosanoids by inhibition of cyclooxygenase-1 and cyclooxygenase-2 enzyme activities.
BORRELLI, FRANCESCA, POSADAS I, CAPASSO, RAFFAELE, AVIELLO, GABRIELLA, ASCIONE V, CAPASSO, FRANCESCO   +5 more
openaire   +3 more sources

Encapsulation of caffeic acid phenethyl ester by self-assembled sorghum peptide nanoparticles: Fabrication, storage stability and interaction mechanisms.

Food Chemistry
Caffeic acid phenethyl ester (CAPE) is a naturally occurring phenolic compound with various biological activities. However, poor water solubility and storage stability limit its application. In this context, sorghum peptides were used to encapsulate CAPE.
Hongdong Song, Shaoxia Ren, Xinyue Wang, Yawen Hu, Mingda Xu, Hang Zhang, H. Cao, Kai Huang, Chengtao Wang, Xiao Guan   +9 more
semanticscholar   +1 more source