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Caffeic Acid Phenethyl Ester (CAPE)

Shock, 2014
Excessive free radical production by immune cells has been linked to cell death and tissue injury during sepsis. Peroxynitrite is a short-lived oxidant and a potent inducer of cell death that has been identified in several pathological conditions. Caffeic acid phenethyl ester (CAPE) is an active component of honeybee products and exhibits antioxidant ...
Mustafa, Kassim   +9 more
openaire   +2 more sources

Yeast Metabolic Engineering for Biosynthesis of Caffeic Acid-Derived Phenethyl Ester and Phenethyl Amide

ACS Synthetic Biology, 2023
Caffeic acid (CA)-derived phenethyl ester (CAPE) and phenethyl amide (CAPA) are extensively investigated bioactive compounds with therapeutic applications such as antioxidant, anti-inflammatory, and anticarcinogenic properties. To construct microbial cell factories for production of CAPE or CAPA is a promising option given the limitation of natural ...
Zi-Chen Jia   +6 more
openaire   +2 more sources

The effect of caffeic acid phenethyl ester (CAPE) on tympanosclerosis

International Journal of Pediatric Otorhinolaryngology, 2017
To investigate the effects of caffeic acid phenethyl ester (CAPE) on tympanosclerosis.Thirty-two male Sprague Dawley rats were separated into 4 groups as CAPE (n = 10), alcohol (n = 10), control (n = 8) and normal (n = 4) groups. All tympanic membranes except normal group were myringotomised and type 3 Streptococcus pneumoniae strains was injected into
İbrahim, Ağrı   +8 more
openaire   +2 more sources

Caffeic acid phenethyl ester ameliorates cadmium-induced kidney mitochondrial injury

Chemico-Biological Interactions, 2012
This study examined whether caffeic acid phenethyl ester (CAPE) can protect kidney mitochondria against cadmium toxicity. Kidney mitochondria isolated from Wistar rat were exposed to cadmium and/or CAPE at various concentrations. Mitochondrial function, ultrastructure and oxidative stress status were determined.
Anongporn, Kobroob   +2 more
openaire   +2 more sources

Therapeutic Potential of Caffeic Acid Phenethyl Ester (CAPE) in Diabetes

Current Medicinal Chemistry, 2019
Diabetes mellitus is a complex metabolic disease characterized by high blood sugar levels. Different pathogenic processes are involved in the etiology of the disease. Indeed, chronic diabetes hyperglycemia is often associated with severe long-term complications including cardiovascular symptoms, retinopathy, nephropathy, and neuropathy.
PITTALA', Valeria   +5 more
openaire   +2 more sources

Caffeic acid phenethyl ester prevents intestinal reperfusion injury in rats

Journal of Pediatric Surgery, 1999
Ischemia-reperfusion injury is encountered frequently in conditions that diminish intestinal blood flow. Caffeic acid phenethyl ester (CAPE), which is a specific component of the honeybee hive product propolis, exhibits potential antioxidant properties.
U, Koltuksuz   +8 more
openaire   +2 more sources

Effects of Caffeic Acid Phenethyl Ester (CAPE) on Hepatopulmonary Syndrome

Inflammation, 2010
The aim of this study was to investigate the effects of caffeic acid phenethyl ester (CAPE) on inflammatory and related histopathological changes in the lung and liver in experimental hepatopulmonary syndrome (HPS) model. Forty Sprague Dawley rats were used in this study. The animals were divided into four groups of ten rats each.
Ahmet, Tekin   +8 more
openaire   +2 more sources

Effects of caffeic acid phenethyl ester against multi-species cariogenic biofilms

Folia Microbiologica, 2023
Dental caries is a biofilm-related disease, widely perceived to be caused by oral ecological imbalance when cariogenic/aciduric bacteria obtain an ecological advantage. Compared with planktonic bacteria, dental plaques are difficult to remove under extracellular polymeric substance protection.
Xiaohui Lv   +7 more
openaire   +2 more sources

Effects of Caffeic Acid Phenethyl Ester (CAPE) on Sepsis in Rats

Inflammation, 2008
Sepsis is still a major cause of the high mortality rate in the intensive care unit. Many studies have been published about the severity of sepsis, but the cause of mortality in sepsis and multiorgan failure is still obscure. This study investigated the effects of caffeic acid phenethyl ester (CAPE) particularly on the inflammatory and related ...
Ahmet, Tekin   +7 more
openaire   +3 more sources

Effect of caffeic acid phenethyl ester on gastric acid secretion in vitro

European Journal of Pharmacology, 2005
Caffeic acid phenethyl ester (CAPE), one of the major components of propolis (honeybee resin), has demonstrated a wide spectrum of activities including suppression of eicosanoids by inhibition of cyclooxygenase-1 and cyclooxygenase-2 enzyme activities.
BORRELLI, FRANCESCA   +5 more
openaire   +3 more sources

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