A computational approach to evaluate caffeoylquinic acids and flavonoids in Pluchea indica Less. leaves as potential anti-HIV agents [PDF]
Context: The attachment of human immunodeficiency virus type 1 glycoprotein 120 (HIV-1 gp120) to the CD4 receptor of human immune cells is the beginning of HIV-1 infection.
Ni Putu Ermi Hikmawanti +5 more
doaj +1 more source
Comparative chemomapping of phytoconstituents from different extracts of globe artichoke - Cynara scolymus L. [PDF]
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Cziáky, Zoltán +7 more
core
Anti-mycobacterial assessment and characterization of 5-O-caffeoylquinic acid methyl ester and rutin from Pavetta crassipes [PDF]
Pavetta crassipes leaf (Fam. Rubiaceae) is used as part of a combination herbal remedy for the treatment of tuberculosis (TB) and other respiratory infections in Nigerian ethno medicine.
Haroune, Nicolas +5 more
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In vitro and in vivo antiseptic activities of caffeoylquinic acid
Purpose: To evaluate the antiseptic effect of caffeoylquinic acid (CA) in in vivo and in vitro models.Methods: In vivo sepsis was produced in rats via cecal ligation and puncture (CLP) method. Four groups of rats were used: control group, untreated CLP group, and two CA groups treated with caffeoylquinic acid (50 and 100 mg/kg, p.o.) for 30 days before
Li, Zhaojie +4 more
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The objective of this study was to separate and identify the bioactive compounds in the Robusta coffee brew. The coffee brew showed significant potential for antioxidant, anti-α-glucosidase, and antiglycation activities, as well as effectiveness in ...
Dian Herawati +4 more
doaj +1 more source
Synthesis and antihepatotoxic and antiproliferative activities of di- and tri-O-caffeoylquinic acid derivatives [PDF]
Methyl di- and tri-O-caffeoylquinates were synthesized by esterification of methyl quinate with di-O-acetylcaffeoyl chloride, following deprotection of the acetyl groups. Moreover, 4,5-di-O-caffeoylquinic acid was synthesized by esterification of quinide
BANSKOTA ArjunH. +4 more
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Stevia rebaudiana Bertoni cultivated in Portugal: a prospective study of its antioxidant potential in different conservation conditions [PDF]
Studies with well-established cultivation conditions are of utmost importance in order to standardize the plants production and, therefore, its chemical composition.
Barros, Lillian +5 more
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Cyclodextrin inclusion complexes with caffeoylquinic acids as bioactive compounds
Neochlorogenic acid, a less-studied caffeoylquinic acid, isomer of chlorogenic acid, has been seen to possess antioxidant, antifungal, anti-inflammatory and anticarcinogenic effects, which makes it an interesting bioactive compound for incorporation in drugs, nutraceuticals or functional foods.
Adrián Matencio +3 more
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α-Glucosidase inhibitors decrease the cleavage- and absorption rate of monosaccharides from complex dietary carbohydrates, and represent therefore an important class of drugs for management of type 2 diabetes.
Eder Lana e Silva +4 more
doaj +1 more source
Abstract Recent reports suggest that javamide‐I/‐II found in coffee contain anti‐inflammatory activity greater than 3‐O‐caffeoylquinic acid, 4‐O‐caffeoylquinic acid, 5‐O‐caffeoylquinic acid and caffeine. However, there is little information about javamide‐I/‐II amounts in coffee products, impossible to assess their biological activity.
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