Dynamic Chemical Profiling of <i>Lonicera japonica</i> Flos During the Maceration and Decoction Processes Integrating UPLC-MS and Molecular Networking. [PDF]
Ding H +5 more
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Main characteristic metabolites with xanthine oxidase inhibitory activities from Yunnan <i>Coffea arabica</i> husks. [PDF]
Wang H +5 more
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Evaluation of Sunflower Sprout Extract as a Bioinspired Support to UV Filtration. [PDF]
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Natural products as potential anticonvulsants: Caffeoylquinic acids
Archives of Pharmacal Research, 2012Current anticonvulsant therapies are generally directed at symptomatic treatment by suppressing excitability within the brain. Consequently, they have adverse effects such as cognitive impairment, dependence, and abuse. The need for more effective and less toxic anticonvulsants has generated renewed interest in natural products for the treatment of ...
Hyo Geun, Kim, Myung Sook, Oh
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To investigate the mechanism of binding of human serum albumin (HSA) with potential sensitinogen, including chlorogenic acid and two isochlorogenic acids (3,4-di-O-caffeoylquinic acid and 3,5-di-O-caffeoylquinic acid).By using the docking algorithm of computer-aided molecular design and the Molegro Virtual Docker, the crystal structures of HSA with ...
Jing, Zhou +4 more
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Caffeoylquinic Acids: Separation Method, Antiradical Properties and Cytotoxicity
Chemistry & Biodiversity, 2019AbstractTwelve chlorogenic acid derivatives and two flavones were isolated from Moquiniastrum floribundum (Asteraceae, other name: Gochnatia floribunda). Compounds were evaluated in relation to their cytotoxicity and antiradical properties. Cytotoxicity was not observed for compounds, however, chlorogenic acid derivatives showed antiradical activity ...
Cinthia Indy Tamayose +4 more
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Inhibitory mechanism of xanthine oxidase activity by caffeoylquinic acids in vitro
International Journal of Biological Macromolecules, 2021In this study, the inhibitory activities of eight caffeoylquinic acids (CQAs) against xanthine oxidase (XOD) in vitro were investigated, and the interaction mechanisms between each compound and XOD were studied. HPLC and fluorescence spectra showed that the inhibitory activities of dicaffeoylquinic acids (diCQAs) were higher than that of ...
Yin, Wan +6 more
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Comparative study of the antioxidative activities of caffeoylquinic and caffeic acids
Food Chemistry, 2016A detailed conformational analysis was performed to determine the most stable conformers of chlorogenic, cryptochlorogenic, and neochlorogenic acids. The simulated and experimental NMR spectra of caffeoylquinic acids are in excellent agreement. The bond dissociation enthalpies, proton affinities, electron transfer enthalpies, ionisation potentials, and
Svetlana, Marković, Jelena, Tošović
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CAFFEOYLQUINIC ACIDS BIOSYNTHESIS AND ACCUMULATION IN CYNARA CARDUNCULUS: STATE OF THE ART
Acta Horticulturae, 2013Plant secondary metabolites are highly evolved compounds performing different functions, and have been widely exploited from food to medicine. A constant supply of phenols, a class of secondary metabolites, provides preventive and defensive mechanisms to reduce the risk of chronic diseases in human beings; among them mono- and di-caffeoylquinic acids ...
MOGLIA, Andrea +8 more
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