Results 171 to 180 of about 5,958,372 (224)

5-O-Caffeoylquinic acid: A spectroscopic study and biological screening for antimicrobial activity

LWT - Food Science and Technology, 2016
Monika Kalinowska, Piotr Borowski, Leszek Siergiejczyk   +2 more
exaly   +2 more sources

4,5-di-O-caffeoylquinic acid methyl ester isolated from Lonicera japonica Thunb. targets the Keap1/Nrf2 pathway to attenuate H2O2-induced liver oxidative damage in HepG2 cells.

Phytomedicine, 2020
BACKGROUND 4,5-di-O-caffeoylquinic acid methyl ester (4,5-CQME) is a caffeoylquinic acid (CQA) isolated from Lonicera japonica Thunb., a traditional Chinese medicine.
Lingyun Xiao, Shu Liang, Lanlan Ge, Haoqiang Wan, Weigang Wu, J. Fei, Shiping Wu, Boping Zhou, Xiaobin Zeng   +8 more
semanticscholar   +1 more source

Natural products as potential anticonvulsants: Caffeoylquinic acids

Archives of Pharmacal Research, 2012
Current anticonvulsant therapies are generally directed at symptomatic treatment by suppressing excitability within the brain. Consequently, they have adverse effects such as cognitive impairment, dependence, and abuse. The need for more effective and less toxic anticonvulsants has generated renewed interest in natural products for the treatment of ...
Hyo Geun, Kim, Myung Sook, Oh
openaire   +2 more sources

3,4,5-Tri-O-caffeoylquinic acid methyl ester isolated from Lonicera japonica Thunb. Flower buds facilitates hepatitis B virus replication in HepG2.2.15 cells.

Food and Chemical Toxicology, 2020
Caffeoylquinic acids are well known for their prominent antiviral activities. Beyond our expectations, we initially found 3,4,5-Tri-O-caffeoylquinic acid methyl ester (3,4,5-CQME) from L. japonica can facilitate HBV DNA and antigens secretion. This study
Haoqiang Wan, Lanlan Ge, Lingyun Xiao, Jiemei Li, Weigang Wu, Shusong Peng, Jian Huang, Boping Zhou, Xiaobin Zeng   +8 more
semanticscholar   +1 more source

Molecular docking of chlorogenic acid, 3,4-di-O-caffeoylquinic acid and 3,5-di-O-caffeoylquinic acid with human serum albumin

Journal of Chinese Integrative Medicine, 2012
To investigate the mechanism of binding of human serum albumin (HSA) with potential sensitinogen, including chlorogenic acid and two isochlorogenic acids (3,4-di-O-caffeoylquinic acid and 3,5-di-O-caffeoylquinic acid).By using the docking algorithm of computer-aided molecular design and the Molegro Virtual Docker, the crystal structures of HSA with ...
Jing, Zhou, Hong-yue, Ma, Xin-sheng, Fan, Wei, Xiao, Tuan-jie, Wang   +4 more
openaire   +2 more sources

Inhibitory mechanism of xanthine oxidase activity by caffeoylquinic acids in vitro

International Journal of Biological Macromolecules, 2021
In this study, the inhibitory activities of eight caffeoylquinic acids (CQAs) against xanthine oxidase (XOD) in vitro were investigated, and the interaction mechanisms between each compound and XOD were studied. HPLC and fluorescence spectra showed that the inhibitory activities of dicaffeoylquinic acids (diCQAs) were higher than that of ...
Yin, Wan, Jin, Qian, Yizhen, Li, Yuefeng, Shen, Yanru, Chen, Guiming, Fu, Mingyong, Xie   +6 more
openaire   +2 more sources

Caffeoylquinic acid derivatives from the roots of Arctium lappa L. (burdock) and their structure–activity relationships (SARs) of free radical scavenging activities

Phytochemistry Letters, 2016
Xiao-Long Hu, Qingchun Zhao, Yanhua Fan   +2 more
exaly   +2 more sources

Caffeoylquinic Acids: Separation Method, Antiradical Properties and Cytotoxicity

Chemistry & Biodiversity, 2019
AbstractTwelve chlorogenic acid derivatives and two flavones were isolated from Moquiniastrum floribundum (Asteraceae, other name: Gochnatia floribunda). Compounds were evaluated in relation to their cytotoxicity and antiradical properties. Cytotoxicity was not observed for compounds, however, chlorogenic acid derivatives showed antiradical activity ...
Cinthia Indy Tamayose, Evelyne A. dos Santos, Nádia Roque, Letícia V. Costa‐Lotufo, Marcelo J. Pena Ferreira   +4 more
openaire   +2 more sources

Glucosylated caffeoylquinic acid derivatives from the flower buds of Lonicera japonica

Acta Pharmaceutica Sinica B, 2015
Three new glucosylated caffeoylquinic acid isomers (1-3), along with six known compounds, have been isolated from an aqueous extract of the flower buds of Lonicera japonica. Structures of the new compounds were determined by spectroscopic and chemical methods as (-)-4-O-(4-O-β-d-glucopyranosylcaffeoyl)quinic acid (1), (-)-3-O-(4-O-β-d ...
Yongchun Yang, Yuhuan Li, Jian-Dong Jiang   +2 more
exaly   +4 more sources

Comparative study of the antioxidative activities of caffeoylquinic and caffeic acids

Food Chemistry, 2016
A detailed conformational analysis was performed to determine the most stable conformers of chlorogenic, cryptochlorogenic, and neochlorogenic acids. The simulated and experimental NMR spectra of caffeoylquinic acids are in excellent agreement. The bond dissociation enthalpies, proton affinities, electron transfer enthalpies, ionisation potentials, and
Svetlana, Marković, Jelena, Tošović
openaire   +2 more sources