Results 191 to 200 of about 5,958,372 (224)

Antioxidant extracts of coffee leaves and its active ingredient 5-caffeoylquinic acid reduce chemically-induced inflammation in mice

Industrial crops and products (Print), 2018
Leaves from Coffea arabica L. have been considered an agricultural residue of little value; however, these leaves are a potentially sustainable source of phenolic compounds.
Luciana Segheto, B. Santos, A. F. Werneck, F. M. P. Vilela, O. Sousa, M. P. Rodarte   +5 more
semanticscholar   +1 more source

Caffeoylquinic Acids in Centella asiatica Protect against Amyloid-β Toxicity [PDF]

Journal of Alzheimer's Disease, 2014
The accumulation of amyloid-β (Aβ) is a hallmark of Alzheimer's disease and is known to result in neurotoxicity both in vivo and in vitro. We previously demonstrated that treatment with the water extract of Centella asiatica (CAW) improves learning and memory deficits in Tg2576 mice, an animal model of Aβ accumulation.
Nora E, Gray, Jeff, Morré, Jeremiah, Kelley, Claudia S, Maier, Jan F, Stevens, Joseph F, Quinn, Amala, Soumyanath   +6 more
openaire   +2 more sources

Preparative separation of caffeoylquinic acid isomers from Lonicerae japonicae Flos by pH-zone-refining counter-current chromatography and a strategy for selection of solvent systems with high sample loading capacities.

Journal of Chromatography A, 2018
Caffeoylquinic acid derivatives exhibit anti-inflammatory, antioxidant, and antibacterial activities. We successfully applied pH-zone-refining counter-current chromatography (pH-ZRCCC) to separation of isomeric caffeoylquinic acids from Lonicerae ...
Tianyu Ma, Hongjing Dong, Heng Lu, Hengqiang Zhao, Lanping Guo, Xiao Wang   +5 more
semanticscholar   +1 more source

Di-caffeoylquinic acid: a potential inhibitor for amyloid-beta aggregation

Journal of Natural Medicines
Alzheimer's disease (AD) remains a challenging neurodegenerative disorder with limited therapeutic success. Traditional Chinese Medicine (TCM), as a promising new source for AD, still requires further exploration to understand its complex components and mechanisms.
Yue Sun, Xue Wang, Xiaoyu Zhang, Yan Li, Dongdong Wang, Feng Sun, Cunli Wang, Zhenqiang Shi, Xindi Yang, Zhiying Yang, Haijie Wei, Yanling Song, Guangyan Qing   +12 more
openaire   +2 more sources

Current Advances in Naturally Occurring Caffeoylquinic Acids: Structure, Bioactivity, and Synthesis

Journal of Agricultural and Food Chemistry, 2020
Caffeoylquinic acids (CQAs) are a broad class of secondary metabolites that have been found in edible and medicinal plants from various families. It has been 100 years since the discovery of chlorogenic acid in 1920. In recent years, a number of naturally derived CQAs have been isolated and structurally elucidated. Accumulated evidence demonstrate that
Wenwu Liu, Jingda Li, Xuemei Zhang, Yuxin Zu, Yue Yang, Wenjie Liu, Zihua Xu, Huan Gao, Xue Sun, Xiaowen Jiang, Qingchun Zhao   +10 more
openaire   +2 more sources

Characterization of polyphenol oxidase from purple sweet potato (Ipomoea batatas L. Lam) and its affinity towards acylated anthocyanins and caffeoylquinic acid derivatives.

Food Chemistry, 2021
Andrea Torres, G. Aguilar-Osorio, Michelle Camacho, F. Basurto, A. Navarro-Ocaña   +4 more
semanticscholar   +1 more source

Caffeoylquinic acids

2021
Dorota Woźniak, Izabela Nawrot-Hadzik, Weronika Kozłowska, Sylwester Ślusarczyk, Adam Matkowski   +4 more
openaire   +2 more sources

Spectroscopic studies of the interaction mechanisms between mono-caffeoylquinic acids and transferrin

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2017
Transferrin (Tf) is an important protein responsible for circulating and transporting iron into cytoplasm. Tf can be taken into cells through endocytosis mediated by Tf receptor, which usually overexpresses in cancer cells. The Tf-Tf receptor pathway opens a possible avenue for novel targeted cancer therapy by utilizing Tf-binding active compounds ...
Yanqing, Guan, Jing, Dong, Shizhong, Chen, Meixian, Liu, Daidong, Wang, Xiaotian, Zhang, Hong, Wang, Zongtao, Lin   +7 more
openaire   +2 more sources

The rolC gene increases caffeoylquinic acid production in transformed artichoke cells

Applied Microbiology and Biotechnology, 2014
Caffeoylquinic acids are found in artichokes, and they are currently considered important therapeutic or preventive agents for treating Alzheimer's disease and diabetes. We transformed artichoke [the cultivated cardoon or Cynara cardunculus var. altilis DC (Asteraceae)] with the rolC gene, which is a known inducer of secondary metabolism.
Y V, Vereshchagina, V P, Bulgakov, V P, Grigorchuk, V G, Rybin, G N, Veremeichik, G K, Tchernoded, T Y, Gorpenchenko, O G, Koren, N H T, Phan, N T, Minh, L T, Chau, Y N, Zhuravlev   +11 more
openaire   +2 more sources

[Caffeoylquinic acid derivatives from stems of Akebia trifoliata].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015
To study the chemical constituents from Akebia trifoliata stems.The compounds were isolated and purified by column chromatography, and their structures were determined through spectroscopic techniques and physicochemical properties.Six compounds were isolated from the stems of Akebia trifolita and identified as cryptochlorogenic acid methyl ester (1 ...
Jing, Wang, Qiao-Lin, Xu, Zhong-Yu, Zhou, Jian-Wen, Tan   +3 more
openaire   +1 more source