Results 61 to 70 of about 12,893 (221)

Synthesis and In Vitro Evaluation of Caffeoylquinic Acid Derivatives as Potential Hypolipidemic Agents. [PDF]

Molecules, 2019
A series of novel caffeoylquinic acid derivatives of chlorogenic acid have been designed and synthesized. Biological evaluation indicated that several synthesized derivatives exhibited moderate to good lipid-lowering effects on oleic acid-elicited lipid accumulation in HepG2 liver cells.
Tian Y, Cao XX, Shang H, Wu CM, Zhang X, Guo P, Zhang XP, Xu XD.   +7 more
europepmc   +5 more sources

Unravelling polyphenol skin permeation: A comparative study using full‐thickness 3D in vitro and ex vivo human skin models

International Journal of Cosmetic Science, EarlyView.
This study demonstrates that full‐thickness 3D in vitro skin models reliably assess the permeation of cosmetic polyphenols, revealing compound‐specific transport profiles and bridging the gap between conventional cell models and ex vivo human skin, while offering an ethical and robust alternative for dermal absorption screening. Abstract The evaluation
Mariana Marques, Filipa Teixeira, Mónica Vieira, M. Helena Amaral, Paulo C. Costa, Stefano Dall'Acqua, Francisca Rodrigues   +6 more
wiley   +1 more source

The effects of a (poly)phenol‐rich food intervention on markers of exercise‐induced inflammation and oxidative stress: A randomised controlled trial

Experimental Physiology, EarlyView.
Abstract This study examined whether consuming a (poly)phenol‐rich food before strenuous muscle‐damaging exercise can modify post‐exercise markers of inflammation and oxidative stress. Using a double‐blinded, randomised, placebo‐controlled, between‐subjects design, 26 recreationally active males (n = 15) and females (n = 11) consumed higher‐(poly ...
Abrar Al Hebshi, Josh Thorley, Ana Rodriguez‐Mateos, Zicheng Zhang, Lewis J James, Tom Clifford   +5 more
wiley   +1 more source

Recent Advances in Biosynthesis and Bioactivity of Plant Caffeoylquinic Acids

Current Issues in Molecular Biology
Caffeoylquinic acids (CQAs), a class of phenolic acid metabolites widely distributed in plants, encompass 15 positional isomers from mono- to tetra-esters, with 5-O-caffeoylquinic acid (5-CQA) as the predominant form. The biosynthesis of 5-CQA from phenylalanine proceeds through five primary pathways, which are finely regulated by environmental ...
Hanqin Chen, Bo Pan, Shilong Zhang, Xin Li, Yuyao Zhang, Kang Gao, Dongliang Chen, Lili Wang, Tianhua Jiang, Chang Luo, Conglin Huang   +10 more
openaire   +3 more sources

Caffeoylquinic acids in leaves of selected Apocynaceae species: Their isolation and content

Pharmacognosy Research, 2014
Pharmacognosy Research,2014,6,1,: 67-72.DOI:10.4103/0974-8490.122921Published:December,2013Type:Original ArticleAuthors:Siu Kuin Wong, Yau Yan Lim, Sui Kiong Ling, and Eric Wei Chiang Chan Author(s) affiliations:Siu Kuin Wong1, Yau Yan Lim1, Sui Kiong Ling2, Eric Wei Chiang Chan3 1School of Science, Monash University Sunway Campus, Bandar Sunway, 46150
Eric Wei Chiang Chan, Siu-Chung Wong, Young Ae Lim, SuiKiong Ling   +3 more
openaire   +3 more sources

Characterization of Grape Cane Stilbenoids and Their Photo‐Degradation Products by HPLC‐DAD Coupled With Trapped Ion Mobility Spectrometry and High‐Resolution Tandem Mass Spectrometry

Rapid Communications in Mass Spectrometry, Volume 40, Issue 15, 15 August 2026.
ABSTRACT Rationale Bioactive (E)‐stilbenoids in vine extracts are prone to light‐induced transformation into the respective (Z)‐isomers and further degradation products, often resulting in a loss of bioactivity. We sought to study stilbenoid degradation beyond that of the well‐researched resveratrol due to the high diversity of stilbenoids in nature ...
Paul Besrukow, Friederike A. Schnitker, Ralf Schweiggert, Christof B. Steingass   +3 more
wiley   +1 more source

Phytochemical content and antioxidant activity in aqueous extracts of Cyclocarya paliurus leaves collected from different populations [PDF]

PeerJ, 2019
Cyclocarya paliurus (Batal) Iljinskaja is a multiple function tree species, but its main utilization is for the harvesting of its leaves as materials for tea production and recently as ingredients for the food industry.
Mingming Zhou, Yuan Lin, Shengzuo Fang, Yang Liu, Xulan Shang   +4 more
doaj   +2 more sources

Artemisia gmelinii Attenuates Lung Inflammation by Suppressing the NF-κB/MAPK Pathway

Antioxidants, 2022
Cigarette smoke (CS) is the main cause of chronic obstructive pulmonary disease (COPD), and continuous CS exposure causes lung inflammation and deterioration.
Seung Yong Kim, Dong-Uk Shin, Ji-Eun Eom, Sun Young Jung, Hyeon-Ji Song, Kyung min Lim, Gun-Dong Kim, Soon-Il Yun, Mi-Yeon Kim, Hee Soon Shin, So-Young Lee   +10 more
doaj   +1 more source

Isolation and mapping of a C3'H gene (CYP98A49) from globe artichoke, and its expression upon UV-C stress [PDF]

, 2009
Globe artichoke represents a natural source of phenolic compounds with dicaffeoylquinic acids along with their biosynthetic precursor chlorogenic acid (5-caffeoylquinic acid) as the predominant molecules. We report the isolation and characterization of a
Acquadro, A., Beekwilder, M.J., Comino, C., Lanteri, S., Moglia, A., Portis, E., Vos, C.H., de   +6 more
core   +2 more sources

Neuroprotective effects of 3,5-di-o-caffeoylquinic acid in vitro and in vivo [PDF]

BMC Proceedings, 2011
BackgroundCaffeoylquinic acid (CQA) derivatives are natural func-tional compounds isolated from a variety of plants andpossess a broad range of pharmacological properties,including antioxidant, hepatoprotectant, antibacterial,antihistaminic, anticancer, and other biological effects[1].
Han Junkyu, Isoda Hiroko
openaire   +3 more sources