Results 41 to 50 of about 7,148 (171)

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

Phytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko, Victoriya Georgiyants, Liudas Ivanauskas, Olha Mykhailenko   +3 more
wiley   +1 more source

Unravelling polyphenol skin permeation: A comparative study using full‐thickness 3D in vitro and ex vivo human skin models

International Journal of Cosmetic Science, EarlyView.
This study demonstrates that full‐thickness 3D in vitro skin models reliably assess the permeation of cosmetic polyphenols, revealing compound‐specific transport profiles and bridging the gap between conventional cell models and ex vivo human skin, while offering an ethical and robust alternative for dermal absorption screening. Abstract The evaluation
Mariana Marques, Filipa Teixeira, Mónica Vieira, M. Helena Amaral, Paulo C. Costa, Stefano Dall'Acqua, Francisca Rodrigues   +6 more
wiley   +1 more source

Geometrical isomerization of hydroxycinnamic acid under UV‐light: Structural plasticity as a driver of metabolite complexity

Photochemistry and Photobiology, EarlyView.
UV irradiation drives metabolite complexity through photoisomerization of hydroxycinnamic acid‐containing compounds in plants. The olefin functional group of hydroxycinnamic acid enables structural plasticity through trans/cis isomerization. Multiple chromophores within a molecule can amplify UV‐induced transformations.
Mailane Rose Sekgobela, Lutendo Michael Mathomu, Nakisani Babra Moyo, Rudzani Nemadzhilili, Mwadham Mwombeki Kabanda, Ntakadzeni Edwin Madala   +5 more
wiley   +1 more source

The effects of a (poly)phenol‐rich food intervention on markers of exercise‐induced inflammation and oxidative stress: A randomised controlled trial

Experimental Physiology, EarlyView.
Abstract This study examined whether consuming a (poly)phenol‐rich food before strenuous muscle‐damaging exercise can modify post‐exercise markers of inflammation and oxidative stress. Using a double‐blinded, randomised, placebo‐controlled, between‐subjects design, 26 recreationally active males (n = 15) and females (n = 11) consumed higher‐(poly ...
Abrar Al Hebshi, Josh Thorley, Ana Rodriguez‐Mateos, Zicheng Zhang, Lewis J James, Tom Clifford   +5 more
wiley   +1 more source

The Development of a Simple Liquid Chromatography‐Precursor Ion Scan‐Mass Spectrometry Screening Method for the Detection of Phytocannabinoids in Plant Extracts

Journal of Mass Spectrometry, Volume 61, Issue 11, November 2026.
ABSTRACT Screening of major cannabinoids in cannabis‐derived extracts is needed when these extracts are applied in pharmacological and biological studies. Precursor ion scan‐mass spectrometry (PIS‐MS) is a viable approach for the detection and screening of major cannabinoids through characteristic MS/MS fragmentation behavior.
Radwa Mahmoud, Deborah Michel, Fatma Elessawy, Randy W. Purves, Robert B. Laprairie, Anas El‐Aneed   +5 more
wiley   +1 more source

Artemisia gmelinii Attenuates Lung Inflammation by Suppressing the NF-κB/MAPK Pathway

Antioxidants, 2022
Cigarette smoke (CS) is the main cause of chronic obstructive pulmonary disease (COPD), and continuous CS exposure causes lung inflammation and deterioration.
Seung Yong Kim, Dong-Uk Shin, Ji-Eun Eom, Sun Young Jung, Hyeon-Ji Song, Kyung min Lim, Gun-Dong Kim, Soon-Il Yun, Mi-Yeon Kim, Hee Soon Shin, So-Young Lee   +10 more
doaj   +1 more source

Gastric Cancer: Epidemiology, Risk Factors, Pathogenesis, Clinical Features, Diagnosis, and Management

MedComm, Volume 7, Issue 11, November 2026.
This comprehensive review summarizes gastric cancer epidemiology, multifactorial risk factors (like infectious, dietary, genetic), pathogenesis such as precancerous evolution, molecular alterations, and a focus on the bidirectional interactions between gastric cancer cells and macrophages in the tumor microenvironment.
Yixuan Xin, Xingya Wang, Yangtao Wu, Qian Liu, Qian Ren, Hui Wang, Jingbo Zhai   +6 more
wiley   +1 more source

Neuroprotective effects of 3,5-di-o-caffeoylquinic acid in vitro and in vivo [PDF]

BMC Proceedings, 2011
BackgroundCaffeoylquinic acid (CQA) derivatives are natural func-tional compounds isolated from a variety of plants andpossess a broad range of pharmacological properties,including antioxidant, hepatoprotectant, antibacterial,antihistaminic, anticancer, and other biological effects[1].
Han Junkyu, Isoda Hiroko
openaire   +3 more sources

Peumus boldus: Revealing the Pharmaceutical Potential of the Chilean Forest

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
P. boldus emerge as a promising yet underexplored source of bioactive compounds. Current evidence highlights antioxidant, anti‐inflammatory, antimicrobial, and cytoprotective activities associated with their unique phytochemical profile. This review integrates chemical composition, biological properties, proposed molecular mechanisms, and safety ...
Marta Rodríguez‐Ceballos, Valentina Jara, Sofía Díaz‐Cornejo, Valentina Morales, Rómulo Santelices‐Moya, Miguel Aguilera, Cristian Atala, María Carolina Otero, Felipe Gordillo‐Fuenzalida   +8 more
wiley   +1 more source

Exploration of Degradation Mechanism of Chlorogenic Acids in Stevia Based on UPLC-QTOF MS/MS

Zhipu Xuebao
Chlorogenic acids (caffeoylquinic acids, CQAs), as key bioactive components in numerous traditional herbal medicines, are highly acclaimed for their various biological activities and therapeutic benefits.
Juan-juan WU, Zi-xuan WANG, Yun-he LIAN, Li-juan HOU, Zhi-ping NIU, Wen-chang WANG, Di WU   +6 more
doaj   +1 more source