Results 171 to 180 of about 33,292 (260)

Investigating the Possibility of Wolbachia‐ and Cardinium‐Induced Parthenogenesis in Two Mite Species

New Zealand Journal of Zoology, Volume 53, Issue 3, September 2026.
In arthropods, thelytokous parthenogenesis, in which females develop from unfertilised eggs, is often associated with reproductive manipulation by endosymbiotic bacteria such as Wolbachia and Cardinium. This study investigated whether thelytokous parthenogenesis in two mite species, Amblyseius herbicolus (Phytoseiidae) and Czenspinskia ...
Keshi Zhang, Zhi‐Qiang Zhang
wiley   +1 more source

Mutant huntingtin exon 1 protein detected in mouse brain with neoepitope antibody: effects of CAG repeat expansion, MutS Homolog 3 silencing and aggregation. [PDF]

Brain Commun
Sapp E, Boudi A, Iwanowicz A, Belgrad J, Miller R, Robertson R, O'Reilly D, Yamada K, Deng Y, Joni M, Li X, Kegel-Gleason K, Khvorova A, Reiner A, Aronin N, DiFiglia M.   +15 more
europepmc   +1 more source

A Review of the Therapeutic Potential of Stem Cell‐Derived Nanocarriers to Treat Neurological Disorders

ChemistryOpen, Volume 15, Issue 9, September 2026.
Neurological disorders (NDs) are characterized by substantial loss of specific neurons, with Alzheimer's and Parkinson's diseases being the most frequent NDs and nearly 99% of all “foreign substances” are prohibited from entering the brain by the blood‐brain barrier (BBB) and the blood‐cerebrospinal fluid barrier (CFB).
Nnamdi Ikemefuna Okafor, Ahmed Abdelgader, Magdi Abobaker, Yahya E. Choonara   +3 more
wiley   +1 more source

Mutant huntingtin protein decreases with CAG repeat expansion: implications for therapeutics and bioassays. [PDF]

Brain Commun
Landles C, Osborne GF, Phillips J, Canibano-Pico M, Nita IM, Ali N, Bobkov K, Greene JR, Sathasivam K, Bates GP.   +9 more
europepmc   +1 more source

The Mycobacterium tuberculosis Rv0132c Gene Product Mtb‐FGD2 Can Act as an F420‐Dependent Glucose Dehydrogenase

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 9, Page 1610-1627, September 2026.
ABSTRACT The role of the cell envelope‐associated Rv0132c/FGD2 from Mycobacterium tuberculosis has long been a subject of debate. Importantly, FGD2 is found only in pathogenic mycobacteria, making it a potential drug target. While some suggest it functions as a glucose‐6‐phosphate dehydrogenase, others propose it acts instead as an F420‐dependent ...
Adewale V. Aderemi, Matthew Snee, Richard B. Tunnicliffe, Linus O. Johanissen, Matthew J. Cliff, Colin W. Levy, Derren J. Heyes, Marina Golovanova, Thomas A. Jowitt, Sam Hay, Andrew W. Munro, Jonathan P. Waltho, David Leys   +12 more
wiley   +1 more source

A Population-Wide Exploration of the THAP11 CAG Repeat Size and Structure in the 100,000 Genomes Project and UK Biobank. [PDF]

Mov Disord
Clarkson C, Chen Z, Rocca C, Jadhav B, Ibañez K, Ryten M, Sharp AJ, Houlden H, Tucci A.   +8 more
europepmc   +1 more source

Technologies for engineering repetitive DNA

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Repetitive DNA, a fundamental architectural element of genomes, is widespread across organisms and comprises about 54% of the human genome. With advances in long‐read sequencing and bioinformatics approaches, highly repetitive sequences can now be characterized in depth.
Shuting Ma, Yali Cui, Yi Wu
wiley   +1 more source

In vivo CRISPR-Cas9 genome editing in mice identifies genetic modifiers of somatic CAG repeat instability in Huntington's disease. [PDF]

Nat Genet
Mouro Pinto R, Murtha R, Azevedo A, Douglas C, Kovalenko M, Ulloa J, Crescenti S, Burch Z, Oliver E, Kesavan M, Shibata S, Vitalo A, Mota-Silva E, Riggs MJ, Correia K, Elezi E, Demelo B, Carroll JB, Gillis T, Gusella JF, MacDonald ME, Wheeler VC.   +21 more
europepmc   +1 more source

A CAG repeat threshold for therapeutics targeting somatic instability in Huntington’s disease

, 2023
Aldous SG, Smith EJ, Landles C, Osborne GF, Cañibano-Pico M, Nita IM, Phillips J, Zhang Y, Jin B, Hirst MB, Benn CL, Bond BC, Edelmann W, Greene JR, Bates GP.   +14 more
europepmc   +1 more source

Complete Chloroplast Genome of Indonesian Sugarcane (Saccharum ‘Bululawang’): Comparative, Structural, and Evolutionary Analysis of Photosystem I‐Encoding Genes

Journal of Sustainable Agriculture and Environment, Volume 5, Issue 3, September 2026.
ABSTRACT Sugarcane is one of the most important crops, providing the majority of global sugar production and serving as a major feedstock for bioenergy. Increasing demands for sustainable sugar production under climate and productivity constraint have intensified the need for molecular‐level characterization of elite cultivars.
Widhi Dyah Sawitri, Dwi Kusuma Wahyuni, Triono Bagus Saputro, Denianto Agung Wicaksono, Muhammad Rafi Fairuza, Tiara Putria Judith, Ganies Riza Aristya   +6 more
wiley   +1 more source