Results 171 to 180 of about 3,893,609 (241)

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Effects of an Unblanched Peanut and/or Peanut Skin Diet on Egg Quality, Egg Lipid Chemistry, and Performance of Hens Housed in a Cage-Free Environment. [PDF]

Animals (Basel)
Toomer OT, Vu TC, Wysocky R, Moraes V, Malheiros R, Read QD, Anderson KE.   +6 more
europepmc   +1 more source

Interleukin‐1α Mediates Pancreatic Fibroblast Activation, Regulates Immune Cell Recruitment and Fibrosis in Acute and Chronic Pancreatitis

Advanced Science, EarlyView.
During pancreatitis, IL‐1α is released from necrotic acinar cells. In response to IL‐1α, pancreatic fibroblasts release chemokines and cytokines that regulate the recruitment of immune cells to the damaged organ. Furthermore, IL‐1α primes fibroblasts, resulting in increased tissue fibrosis during chronic pancreatitis.
Hala Mazloum, Shenja Buchholz, Hanna Schifter, Sabine Ameling, Leif Steil, Ben Lewin Becker, Elke Hammer, Georg Homuth, Uwe Völker, Barbara M. Bröker, Lukas Zierke, Frank Ulrich Weiss, Juliane Glaubitz, Matthias Sendler   +13 more
wiley   +1 more source

The influence of genetic strain on fear and anxiety responses of laying hens housed in a cage-free environment. [PDF]

Poult Sci
Gulabrai BP, Kiess AS, Anderson KE, Pullin AN.   +3 more
europepmc   +1 more source

High‐Performance Violet Phosphorene‐Based Device via Tellurium Doping‐Induced Contact Resistance Reduction

Advanced Science, EarlyView.
Tellurium substitution for phosphorus in violet phosphorus significantly reduces contact resistance, enhancing FET performance under ambient conditions. ABSTRACT Two‐dimensional materials have attracted much attention in various research fields. The phosphorene structures with various allotropes, another type of elemental 2D materials after graphene ...
Zhuorui Wen, Xuewen Zhao, Wenju Zhou, Wenqi Mu, Rui Zhai, Jiazheng Lin, Xin Liu, Kerui Hu, Zhiqi Zhang, Guodong Meng, Yonghong Cheng, Huiyang Gou, Jinying Zhang   +12 more
wiley   +1 more source

Environmental contamination and horizontal transmission of Salmonella Enteritidis among experimentally infected layer pullets in indoor cage-free housing. [PDF]

Poult Sci
Gast RK, Garcia JS, Guraya R, Jones DR, Karcher DM.   +4 more
europepmc   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

Advanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao, Zhiyuan Song, Jingcheng Zhang, Jiaheng Lou, Shuo Zhang, Boqiang Liu, Yunhai Wei, Fengmei Qiu, Tao Jiang, Guangji Zhang   +9 more
wiley   +1 more source

John Cage night ('Every Day Is A Good Day', Hayward Touring Exhibition)

John Cage: 4' 33" John Cage: Radio music for 8 performers John Cage: Child of tree for solo percussion John Cage: Concert for piano & orchestra/Fontana mix Interval John Cage: String Quartet in four parts John Cage: Music for eight John Cage: 0 ...
Thomas, Philip
core  

Abstract Representation of Movement Parameters in Basal Ganglia Output

Advanced Science, EarlyView.
The basal ganglia output provides a scalable velocity/position signal across behavioral contexts, supporting the idea that these variables are represented in the brain as abstract entities rather than as fixed changes in joint angles or specific sets of body effectors.
Ana Silvia Báez‐Cordero, Diana I. Ortega‐Romero, Claudia I. Pérez‐Díaz, Pavel E. Rueda‐Orozco   +3 more
wiley   +1 more source