Results 61 to 70 of about 161,156 (283)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Media Advertising and Ballot Initiatives: An Experimental Analysis [PDF]

open access: yes
Spending on political advertising increases with every election cycle, not only for congressional or presidential candidates, but also for state-level ballot initiatives.
Allender, William J.   +3 more
core   +4 more sources

Consumer Impact of Animal Welfare Regulation in the California Poultry Industry

open access: yesJournal of Agricultural and Resource Economics, 2010
This study examines the consumer welfare impact of animal welfare legislation mandating cage-free egg production in California. We estimate California egg consumers' willingness to pay (WTP) for cage-free eggs using household-level purchase data and ...
William J. Allender, Timothy J. Richards
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Europe’s regulations at risk [PDF]

open access: yes, 2016
This repository item contains a report from the Boston University Global Economic Governance Initiative. The Global Economic Governance Initiative (GEGI) is a research program of the Center for Finance, Law & Policy, the Frederick S.
Ackerman, Frank
core  

The Appeal of Protest Rhetoric: How Moral Entrepreneurs Recruit the Media into Moral Struggles [PDF]

open access: yes, 2019
Whenever the news media feature brand-related moral struggles over issues such as ethicality, fairness, or sustainability, brands often find themselves in the position of the culprit.
Hemetsberger, A.   +2 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Opinions Regarding Farmed Animals [PDF]

open access: yes, 2008
Over 10 billion land-based animals are killed for food each year in the U.S. However, there is significant and growing public awareness and support for improved farmed animal welfare conditions.

core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Farm-Animal Welfare, Legislation, and Trade [PDF]

open access: yes, 2007
The US has among the weakest farm-animal-welfare standards in the developed world. Although improvements in farm-animal welfare are economically feasible, nations and states enacting protective regulation are threatened by competition with cheaper, non ...
Leahy, Cheryl, Matheny, Gaverick
core   +1 more source

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