Results 101 to 110 of about 11,276 (296)

Physiological intracranial calcification in Eastern Indian population-A CT scan study

National Journal of Clinical Anatomy, 2017
Abstract Background and Aims:Knowledge of physiological calcification in brain parenchyma is essential to avoid misinterpretation during radiological evaluation. The calcifications are commonly seen in pineal gland, falx cerebri, tentorium cerebelli and choroid plexus.
Panchali Som, Rajarshi Roy, Sumit Datta, Asis Kumar Ghosal, Anubha Saha, Subhajit Halder   +5 more
openaire   +2 more sources

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Morphogenesis of the Otoconia from the Viewpoint of Physiological Calcification.

Practica Oto-Rhino-Laryngologica, 1996
Although it is known that mammalian otoconia consist of calcium bicarbonate and organic materials, none of the protein components have been identified in mammals at the molecular level, and the mechanism of morphogenesis and calcification of the otoconia remains unclear.
openaire   +2 more sources

Avaliação do efeito do ibandronato na consolidação de fratura: estudo experimental em coelhos Evaluation of ibandronate effects in bone healing: experimental study in rabbits

Revista Brasileira de Ortopedia, 2007
OBJETIVO: Determinar a presença de efeito favorável do ibandronato de sódio na consolidação óssea, contribuindo assim para estudos futuros visando sua utilização terapêutica no tratamento de fraturas e pseudartroses.
Roberto Guarniero, Carlos Eduardo Sanches Vaz, Paulo José de Santana, Éden Dal Molin, Juliana Braun, Marcel Shudi Harada   +5 more
doaj   +1 more source

Computed Tomographic Pattern of Physiological Intracranial Calcifications in a City in Central Africa

Global Journal of Health Science, 2011
Intracranial calcifications underlie certain brain diseases which may be de novo or systemic. But calcifications un-connected to pathologies are classified physiological.To evaluate physiological intracranial calcifications in Douala with establishment of earliest age range of detection.Prospective study of brain computed tomograms was done from April ...
Uduma, Uduma Felix, Pius, Fokam, Mathieu, Motah   +2 more
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Thoracic calcifications on magnetic resonance imaging: correlations with computed tomography

Jornal Brasileiro de Pneumologia
Objective: To identify the characteristics of thoracic calcifications on magnetic resonance (MR) imaging, as well as correlations between MR imaging and CT findings.
Juliana Fischman Zampieri, Gabriel Sartori Pacini, Matheus Zanon, Stephan Philip Leonhardt Altmayer, Guilherme Watte, Marcelo Barros, Evandra Durayski, Gustavo de Souza Portes Meirelles, Marcos Duarte Guimarães, Edson Marchiori, Arthur Soares Souza Junior, Bruno Hochhegger   +11 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source