Results 231 to 240 of about 19,695 (283)

Diagnostic Challenges in Fahr's Disease: A Rare Case of Extensive Basal Ganglia Calcifications. [PDF]

Cureus
Rodenko PN, Slavkovska T, Bhatnagar V, Williams J, Dolun D, Hamra M, Chai E.   +6 more
europepmc   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

Metformin mitigates aortic valve degeneration in an ex vivo three-dimensional tissue model. [PDF]

Sci Rep
Schoettler FI, Weber A, Schmidt V, Bauer SJ, Immohr MB, Lichtenberg A, Akhyari P, Barth M.   +7 more
europepmc   +1 more source

Triazine‐Trione Thermosets with High Processability for Scaffold Applications in Bone Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Novel photo‐clickable triazine‐trione thermosets can be shaped and cured under mild conditions, including room and physiological temperatures. These materials are biocompatible and support osteogenic differentiation of bone marrow–derived mesenchymal stem cells on their surface.
Åshild Johansen, Shuntaro Yamada, Daniel J. Hutchinson, Mohammed A. Yassin, Samih Mohamed‐Ahmed, Cecilie Gjerde, Michael Malkoch, Kamal Mustafa   +7 more
wiley   +1 more source

Cardiac CT in Non-Obstructive Coronary Artery Disease (NOCAD): A Literature Review. [PDF]

J Clin Med
Meossi S, Izzo C, Rotondo L, Sciaramenti G, Menzato E, Dal Passo B, Tezze R, Frascaro F, Tonet E, Marchini F, Campo G, Pavasini R.   +11 more
europepmc   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Mechanisms Linking Insomnia and Cardiometabolic Disease Risk. [PDF]

Arterioscler Thromb Vasc Biol
Fernandez-Mendoza J.
europepmc   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Imaging Findings Associated With Socioenvironmental Exposures Inform Mechanisms of Cardiovascular Disease. [PDF]

Arterioscler Thromb Vasc Biol
Abohashem S, Saeed F, Münzel T, Al-Kindi SG, Foldyna B, Fayad ZA, Tawakol A, Osborne MT.   +7 more
europepmc   +1 more source

3D‐Printed Titanium Implants with Bioactive Peptide‐Polysaccharide Scaffolds for Personalized Bone Reconstruction

Advanced Healthcare Materials, EarlyView.
Porous 3D‐printed titanium implants are made bioactive by integration with a supramolecular peptide‐hyaluronic acid nanofibrillar scaffold, without the addition of exogenous cells or growth factors. Uniform filling of the implant architecture promotes vascularized, spatially homogeneous bone regeneration, significantly enhancing osteogenesis throughout
Noam Rattner, Vladimir Perlis, Eran Golden, Ariel Pokhojaev, Rachel Sarig, Itzhak Binderman, Michal Halperin‐Sternfeld, Solomon Dadia, Lihi Adler‐Abramovich   +8 more
wiley   +1 more source