Results 61 to 70 of about 1,934,605 (322)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Incidence of Stylohyoid Ligament Calcification and Its Length in an Iranian Adult Population

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2011
Introduction: Elongation and calcification of the stylohyoid ligament complex may be correlated with eagle’s syndrome which could cause facial pain or dysphasia.
M Zangouei Booshehri, F Ezoddini Ardakani, A Rasooli, R, Sarayedar Baser, S Nayer   +4 more
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

MO805CAUSAL PATHWAY-BASED PHYSIOLOGICAL MODELING OF VASCULAR CALCIFICATION IN HEMODIALYSIS PATIENTS

Nephrology Dialysis Transplantation, 2021
Abstract Background and Aims Vascular calcification (VC) is common sequelae in chronic and end-stage kidney diseases (CKD/ESKD), and is associated with multiple risk factors, including disturbed bone metabolism and mineral disorders (CKD-BMD), uremia, leading to increased morbidity and mortality.
Alhaji Cherif, Jakob Voelkl, Peter Kotanko   +2 more
openaire   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Retrospective analysis of the incidence of intracranial physiological calcifications with cone beam computed tomography

Selcuk Dental Journal, 2019
Background: The purpose of the present study was to evaluate the incidence of physiologic intracranial calcifications detected in cone beam computed tomography (CBCT) images of in a group Turkish Cypriot population.Methods: The CBCT scans of the full ...
Melis Mısırlı Gülbeş, Berfu Çerci Ongun, Nimet İlke Akçay, Kaan Orhan   +3 more
doaj  

Estudo comparativo da eficácia do etanol e do ácido L-glutâmico na prevenção da calcificação das cúspides e parede aórtica porcina: estudo experimental em ratos Comparative study on the efficacy of ethanol and of l-glutamic acid for preventing calcification of pig cusps and aortic wall: experimental study in rats

Brazilian Journal of Cardiovascular Surgery, 2002
INTRODUÇÃO: As cúspides porcinas tratadas com glutaraldeído (GDA) são um dos tecidos biológicos mais utilizados em biopróteses, porém a calcificação tardia pós-implante constitui a causa predominante de sua falência.
George Ronald Soncini da ROSA, Francisco Diniz Affonso da COSTA, Lismari MESQUITA, Iseu de Santo Elias Affonso da COSTA   +3 more
doaj   +1 more source

Tendinosis develops from age- and oxygen tension-dependent modulation of Rac1 activity. [PDF]

, 2019
Age-related tendon degeneration (tendinosis) is characterized by a phenotypic change in which tenocytes display characteristics of fibrochondrocytes and mineralized fibrochondrocytes.
Edwards, Richard W., Maltenfort, Mitchell G., McBeath, Rowena, O\u27Hara, Brian J., Osterman, A. Lee, Parks, Susan M., Shapiro, Irving M., Steplewski, Andrzej   +7 more
core   +2 more sources

Physiological intracranial calcification in Eastern Indian population-A CT scan study

National Journal of Clinical Anatomy, 2017
Abstract Background and Aims:Knowledge of physiological calcification in brain parenchyma is essential to avoid misinterpretation during radiological evaluation. The calcifications are commonly seen in pineal gland, falx cerebri, tentorium cerebelli and choroid plexus.
Panchali Som, Rajarshi Roy, Sumit Datta, Asis Kumar Ghosal, Anubha Saha, Subhajit Halder   +5 more
openaire   +2 more sources

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source