Results 51 to 60 of about 508,286 (387)
BiomedicinesBackground/Objectives: 7-Methylxanthine (7-MX) is a naturally occurring metabolite of caffeine and theobromine that can inhibit the crystallization of monosodium urate (MSU) and may be useful for the prevention or treatment of gout.
Miguel D. Ferrer +6 more
doaj +1 more source
CDKN2A/p16INK4a expression is associated with vascular progeria in chronic kidney disease [PDF]
, 2017 Patients with chronic kidney disease (CKD) display a progeric vascular phenotype linked to apoptosis, cellular senescence and osteogenic transformation. This has proven intractable to modelling appropriately in model organisms.
Bárány, Peter +13 more
core +1 more source
Molecules, 2018 The pineal gland is a unique organ that synthesizes melatonin as the signaling molecule of natural photoperiodic environment and as a potent neuronal protective antioxidant.
D. Tan +3 more
semanticscholar +1 more source
acta orthopaedica et traumatologica turcica, 2008 Calcific myonecrosis is a rare complication of limb trauma, that may occur after many years. It is characterized by dystrophic calcification that develops in the late period following compartment syndrome usually in the lower limb. We present a 66-year-old man who developed calcific myonecrosis 35 years after surgical intervention for compartment ...
Melih, Güven +5 more
openaire +2 more sources
Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2
Nature Communications, 2019 Vascular calcification is highly prevalent in end-stage renal diseases and is predictive of cardiovascular events and mortality. Poly(ADP-ribose) polymerase 1 (PARP1) inhibition or deletion is vasoprotective in several disease models.
Cheng Wang +7 more
semanticscholar +1 more source
Renal FailureAims This study aimed to investigate the efficacy and safety of sacubitril/valsartan in abnormal renal function (eGFR < 60 ml/min/1.73m2) patients combined with heart failure based on randomized controlled trials (RCTs) and observational studies.Methods ...
Xinyue Yang +4 more
doaj +1 more source
Frontiers in Physiology, 2018 Vascular calcification is the deposition of calcium phosphate minerals in vascular tissue. Vascular calcification occurs by both active and passive processes.
Mary C. Wallingford +6 more
doaj +1 more source
Association Between Homocysteine and Vascular Calcification Incidence, Prevalence, and Progression in the MESA Cohort. [PDF]
, 2020 Background While elevated homocysteine has been associated with calcification in several studies, its importance as a cardiovascular risk factor remains unclear.
Budoff, Matthew J +7 more
core
BMC NephrologyBackground Up to now, there is no unequivocal intervention to mitigate vascular calcification (VC) in patients with hemodialysis. This network meta-analysis aimed to systematically evaluate the clinical efficacy of sodium thiosulfate, bisphosphonates ...
Lei He +5 more
doaj +1 more source
PharmaceuticalsBackground/Objectives: Ectopic calcification is a pathological condition characterized by the mineralization of soft tissues due to the deposition of calcium phosphate crystals.
Miguel D. Ferrer +11 more
doaj +1 more source