Results 61 to 70 of about 221,745 (317)
Cardiovascular calcification [PDF]
The book systematically describes the clinical and scientific aspects of cardiovascular calcification. Chapters detail the mechanisms associated with arterial and valve calcification, relevant risk factors, pathophysiology and the latest therapeutic ...
Henein, Michael,
core +1 more source
Chronic kidney disease (CKD) is associated with gut microbiota alterations that contribute to increased inflammation and the generation of uremic toxins and may worsen the disease progression.
Teresa Obrero +22 more
doaj +1 more source
Circulating microRNAs and vascular calcification in hemodialysis patients
Objective Vascular calcification is common in chronic dialysis patients and is associated with increased morbidity and mortality. However, the role of circulating microRNAs (miRs) in vascular calcification has rarely been investigated.
Chien-Te Lee +4 more
doaj +1 more source
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Diagnostic performance of coronary CT angiography for stenosis detection according to calcium score: systematic review and meta-analysis [PDF]
OBJECTIVES: A systematic review and meta-analysis to assess sensitivity and specificity of coronary CT angiography (CCTA) for significant stenosis at different degrees of coronary calcification.
den Dekker, M.A.M. +9 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Descending aortic calcification increases renal dysfunction and in-hospital mortality in cardiac surgery patients with intraaortic balloon pump counterpulsation placed perioperatively : a case control study [PDF]
Introduction: Acute kidney injury (AKI) after cardiac surgery increases length of hospital stay and in-hospital mortality. A significant number of patients undergoing cardiac surgical procedures require perioperative intra-aortic balloon pump (IABP ...
Tuli, Sagun +24 more
core +1 more source
Seawater carbonate chemistry and coral calcification media pH [PDF]
Ocean acidification typically reduces the calcification rates of massive Porites spp. corals, but increasing seawater temperatures (below the stress and bleaching threshold) can offset this effect.
Hintz, Chris +5 more
core +1 more source
CALCIFICATION AND OSSIFICATION [PDF]
It is the merit of Jacques Loeb to have shown us the necessity of simplifying our methods of attacking biologic problems. Instead of investigating the effects of complex substances on still more complex living organisms, he took up the simplest things imaginable, the familiar inorganic salts, and for his living subject the least complex complete ...
openaire +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source

