Results 71 to 80 of about 407,718 (365)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Calcification rates of station TT011_2-TM13

, 2003
Calcification rates of station TT011_2 ...
William M Balch (6978683), Balch, William M   +1 more
core   +1 more source

ATVB in Focus series on "Vascular Calcification in Diabetes"

Arteriosclerosis, Thrombosis and Vascular Biology, 2016
The continuing increase in the prevalence of diabetes in the general population is predicted to result in a higher incidence of cardiovascular disease. Although the mechanisms of diabetes associated progression of atherosclerosis are not fully understood,
K. Yahagi, F. Kolodgie, C. Lutter, Hiroyoshi Mori, Maria E. Romero, A. Finn, R. Virmani   +6 more
semanticscholar   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Sinomenine attenuates uremia vascular calcification by miR-143-5p

Scientific Reports
Vascular calcification is considered to be a killer of the cardiovascular system, involved inflammation and immunity. There is no approved therapeutic strategy for the prevention of vascular calcification.
Fengyi Yu, Zhong Peng, Ning Gao, Zixu Tang, Zihao Liao, Song Zhao, Shuzhu Zhong, Gloria Umwiza, Hong Huang, Wei Long, Zhangxiu He   +10 more
doaj   +1 more source

Correlation of hs-CRP, NLR and PLR tocardiac valve calcification in maintenance hemodialysis patients

Linchuang shenzangbing zazhi, 2020
Objective To investigate the levels of hypersensitivity C-reaction protein(hs-CRP), neutrophil/lymphocyte ratio(NLR) and platelet lymphocyte ratio(PLR) in patients with maintenance hemodialysis(MHD), and to analyze their correlation with cardiac valve ...
WANG Yun-dan, JIANG Wei-jie
doaj  

A newly established culture method highlights regulatory roles of retinoic acid on morphogenesis and calcification of mammalian limb cartilage

BioTechniques, 2015
During mammalian embryogenesis, sclerotome-derived chondrocytes in the limb bud are arranged into a complicated bone shape with specific areas undergoing hypertrophy and calcification, creating a region-specific mineralized pattern in the cartilage.
Eizo Masuda, Kota Shirai, Kenji Maekubo, Yohei Hirai   +3 more
doaj   +1 more source

Influence of UVA Irradiation on Calcification of Normal Human Dermal Fibroblasts

, 2019
It is well known that ultraviolet rays cause photo-aging. Ultraviolet A (UVA) is the most important factor in photo-aging, especially in human dermis. As investigation of photo-aging in vitro, we previously reported that normal human dermal fibroblast ...
柴田, 雄次, 野村, 道康, イマダ, チアキ, ノムラ, ミチヤス, Yamada, Katsuhisa, 山田, 勝久, 今田, 千秋, 山本, 樹, ヤマダ, カツヒサ, Imada, Chiaki, NOMURA, Michiyasu   +10 more
core   +1 more source

Environmental drivers of calcification in tropical coralline algae

, 2021
In this talk, we will provide an overview of the research we are currently undertaking to understand the influence of the environment, particularly ocean acidification, on the growth and calcification of crustose coralline algae (CCA) in the Great ...
Jeong, Soyoung, Ordonez, Alexandra, Bergstrom, Ellie, Troitzsch, Ulrike, Lewis, Bonnie, Nash, Merinda, Garcia-Uruena, Rocio, Page, Tessa, Kennedy, Emma, Diaz-Pulido, Guillermo   +9 more
core   +1 more source

Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2

Nature Communications, 2019
Vascular calcification is highly prevalent in end-stage renal diseases and is predictive of cardiovascular events and mortality. Poly(ADP-ribose) polymerase 1 (PARP1) inhibition or deletion is vasoprotective in several disease models.
Cheng Wang, Wenjing Xu, J. An, Minglu Liang, Yiqing Li, Fengxiao Zhang, Q. Tong, Kai Huang   +7 more
semanticscholar   +1 more source