Results 61 to 70 of about 372,169 (340)

No compromise between metabolism and behavior of decorator crabs in reduced pH conditions. [PDF]

open access: yes, 2019
Many marine calcifiers experience metabolic costs when exposed to experimental ocean acidification conditions, potentially limiting the energy available to support regulatory processes and behaviors. Decorator crabs expend energy on decoration camouflage
Graeve, Olivia A   +3 more
core   +3 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

ABCC6 is a basolateral plasma membrane protein [PDF]

open access: yes, 2013
RATIONALE:: ABCC6 plays a crucial role in ectopic calcification; mutations of the gene cause pseudoxanthoma elasticum and general arterial calcification of infancy.
Apana, A.   +11 more
core   +4 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Cell typing of biological heart valves prosthesis explanated due to the development of calcium-associated dysfunctions

open access: yesБюллетень сибирской медицины, 2018
Purpose. To perform immunohistochemical typing of cells obtained from calcinated biological heart valve prosthesis removed during reoperations.Materials and methods.
R. A. Mukhamadiyarov   +5 more
doaj   +1 more source

Bioengineering Case Study to Evaluate Complications of Adverse Anatomy of Aortic Root in Transcatheter Aortic Valve Replacement: Combining Biomechanical Modelling with CT Imaging

open access: yesBioengineering, 2020
Gated computed tomography (CT) might not adequately predict occurrence of post-implantation transcatheter aortic valve replacement (TAVR) complications in hostile aortic root as it would require a more complex integration of morphological, functional and
Cristiano Spadaccio   +7 more
doaj   +1 more source

Reconstruction of deglacial sea surface temperatures in the tropical Pacific from selective analysis of a fossil coral [PDF]

open access: yes, 2005
The Sr/Ca of coral skeletons demonstrates potential as an indicator of sea surface temperatures (SSTs). However, the glacial-interglacial SST ranges predicted from Sr/Ca of fossil corals are usually higher than from other marine proxies.
Allison, N.   +5 more
core   +1 more source

Calcific myonecrosis

open access: yesJournal of the Belgian Society of Radiology, 2010
A 58-year-old man presented with a slowly growing painless mass at the anterolateral aspect of his left lower leg. His past history included a severe neuro - vascular damage of the left lower leg, due to an accidental dynamite explosion 34 years previously. During surgery following the accident, he developed compartmental ischemia of the left lower leg.
Peeters, J   +3 more
openaire   +5 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Sinomenine attenuates uremia vascular calcification by miR-143-5p

open access: yesScientific Reports
Vascular calcification is considered to be a killer of the cardiovascular system, involved inflammation and immunity. There is no approved therapeutic strategy for the prevention of vascular calcification.
Fengyi Yu   +10 more
doaj   +1 more source

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