Results 61 to 70 of about 525,088 (390)

Shape-driven segmentation of the arterial wall in intravascular ultrasound images [PDF]

open access: yes, 2007
Segmentation of arterial wall boundaries from intravascular images is an important problem for many applications in the study of plaque characteristics, mechanical properties of the arterial wall, its 3D reconstruction, and its measurements such as ...
Bucher, Susann   +6 more
core   +2 more sources

Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2

open access: yesNature Communications, 2019
Vascular calcification is highly prevalent in end-stage renal diseases and is predictive of cardiovascular events and mortality. Poly(ADP-ribose) polymerase 1 (PARP1) inhibition or deletion is vasoprotective in several disease models.
Cheng Wang   +7 more
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Vascular Access Site Complications Do Not Correlate With Large Sheath Diameter in TAVI Procedures With New Generation Devices

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Vascular complications after transfemoral transcatheter aortic valve implantation (TAVI) are associated with morbidity and mortality. However, consistent predictors have not been identified yet.
Birgid Gonska   +4 more
doaj   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Evidence of bacterial imprints in different types of non-struvite kidney stones

open access: yesBMC Urology
Background Recent studies of renal lithiasis identified bacterial imprints in apatite phosphate stones and mixed calcium oxalate/apatite phosphate stones, neither of which contained struvite.
Felix Grases   +7 more
doaj   +1 more source

Relationship between effective blood flow rate and clinical outcomes in maintenance hemodialysis patients: a single-center study

open access: yesRenal Failure
The association between blood flow rate (BFR) and clinical outcomes in patients undergoing maintenance hemodialysis (MHD) is inconclusive. This retrospective study included 175 patients undergoing MHD treatment between July 2015 and March 2022, divided ...
Zhoucang Zhang   +5 more
doaj   +1 more source

Intracardiac Calcification - An Interesting Chest X-ray Report. [PDF]

open access: yes, 2013
We report a case of chest X-ray finding of mitral annular calcification. Mitral annular calcification is a degenerative process involving the fibrous annulus of the mitral valve.
Anupama, N   +5 more
core  

Reconstruction of deglacial sea surface temperatures in the tropical Pacific from selective analysis of a fossil coral [PDF]

open access: yes, 2005
The Sr/Ca of coral skeletons demonstrates potential as an indicator of sea surface temperatures (SSTs). However, the glacial-interglacial SST ranges predicted from Sr/Ca of fossil corals are usually higher than from other marine proxies.
Allison, N.   +5 more
core   +1 more source

CALCIFICATION OF THE PINEAL [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1918
n ...
Boas,, Scholz,
openaire   +2 more sources

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