Results 191 to 200 of about 662,429 (302)

The Interactions Between Acetylcholine and T‐Cells and Their Role in the Immune System: A Scoping Review

open access: yesImmunology, EarlyView.
Activated T‐cells instigate signalling events leading to the activation of transcription factors, which in turn, act on the nucleus to produce cytokines. We postulate that c‐fos is one of these transcription factors which upregulates the choline acetyltransferase gene responsible for synthesising acetylcholine (ACh).
Jarita Lay, Nicholas Manolios
wiley   +1 more source

Adjunctive Topical Calcineurin Inhibitors During the Treatment of Fungal Keratitis: Practice Patterns and Opinions. [PDF]

open access: yesCornea
Christy J   +7 more
europepmc   +1 more source

Temporal distribution of acute kidney injury–related hospitalizations after initiation of sodium–glucose cotransporter 2 inhibitors: A nationwide claims database analysis in older adults with an independent complementary single‐center eGFR analysis

open access: yesJournal of Diabetes Investigation, EarlyView.
Among 190 older adults who experienced AKI‐related hospitalization after SGLT2 inhibitor initiation, 31.1% were hospitalized within 30 days. In an independent single‐center cohort, sustained early eGFR decline was associated with older age and use of one or two triple‐whammy‐related drug classes.
Kazuya Hiura   +6 more
wiley   +1 more source

Salvage nintedanib plus low-dose ruxolitinib therapy for bronchiolitis obliterans syndrome refractory to calcineurin inhibitors and glucocorticoids after allogeneic transplantation. [PDF]

open access: yesCell Transplant
Luo Y   +15 more
europepmc   +1 more source

European consensus recommendations for nummular eczema: A modified Delphi study

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
The first consensus recommendations for nummular eczema are based on an international modified Delphi study. Sixty‐three experts from 16 countries evaluated 64 statements addressing definition, diagnosis, assessment and treatment. Consensus supports clinical diagnosis, individualized long‐term management, topical and selected systemic therapies, while ...
Mette Deleuran   +6 more
wiley   +1 more source

Disseminated Cryptococcosis under Fingolimod Therapy

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Sven C. Engler   +4 more
wiley   +1 more source

Ruxolitinib cream in adults with moderate atopic dermatitis after failure of other topicals: A randomized trial

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
In adults with moderate AD post‐TCS and ‐TCI, who may otherwise be eligible for systemic therapy, 1.5% ruxolitinib cream improved clinical signs and symptoms in the TRuE‐AD4 study. Abstract Background In patients with moderate atopic dermatitis (AD), topical corticosteroids (TCS) and topical calcineurin inhibitors (TCI) often do not sufficiently ...
José Manuel Carrascosa   +14 more
wiley   +1 more source

Management of chronic urticaria: Current status and future prospect

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Chronic urticaria is driven by mast cell activation through autoimmune, inflammatory, and neuroimmune pathways. A structured approach combining diagnosis, patient‐reported outcomes, stepwise therapy, treatment optimization, monitoring and emerging targeted agents may improve disease control and enable more personalized management.
Andaç Salman   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy