Results 201 to 210 of about 74,317 (300)

Radiation Associated Undifferentiated Pleomorphic Sarcoma of the Neck 2 Decades After External Beam Radiation for Medullary Thyroid Carcinoma: A Case Report and Literature Review. [PDF]

Am J Case Rep
Odisho T, Esmaeilzade S, Laskaris A, Jung S, Tsui JMG, Dumitra S, Mitmaker E.   +6 more
europepmc   +1 more source

Peptide‐Linked Bivalent Nanobody Constructs as Positive Allosteric Modulators of the Calcium‐Sensing Receptor

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 6, December 2026.
ABSTRACT We previously developed nanobodies acting as positive allosteric modulators (PAMs) of the calcium‐sensing receptor (CaSR). Here, we sought to develop more potent CaSR modulators by creating bivalent nanobody constructs using ‘tail‐to‐head’ peptide‐linker conjugation.
Mahdis Nabipour, Charlotte Hagen Skadhauge, Line Juel Rasmussen, Hans Bräuner‐Osborne, Jesper M. Mathiesen, Anders A. Jensen   +5 more
wiley   +1 more source

Amylin Analogs: The Next Major Class of Weight Loss Therapy: A Review of Experimental Data and Early-Phase Clinical Trials. [PDF]

Diabetes Obes Metab
Alhazmi A, le Roux CW.
europepmc   +1 more source

Incretin‐Based Therapies as Cardiometabolic Interventions: Outcome Hierarchy, Receptor‐Network Pharmacology and Phenotype‐Based Clinical Positioning

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 10977-10991, December 2026.
ABSTRACT Aims Incretin‐based pharmacotherapy was initially developed to improve glucose‐dependent insulin secretion and glycaemic control in type 2 diabetes, but its clinical interpretation has expanded substantially with cardiovascular outcome trials, kidney outcome data, obesity studies and next‐generation polyagonist development.
Ferenc Sztanek, Hajnalka Lőrincz, Mariann Harangi, Attila Csaba Nagy   +3 more
wiley   +1 more source

Hair loss in the era of CGRP inhibition: emerging evidence, mechanisms, and clinical implications. [PDF]

Front Neurol
Antanaitytė A, Jokubaitis M, Jokubaitė J, Ryliškienė K.   +3 more
europepmc   +1 more source

GLP‐1 receptor agonists and serious adverse events: Evidence, uncertainty and clinical implications

Journal of Internal Medicine, Volume 300, Issue 6, Page 758-778, December 2026.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists provide benefits in weight reduction, glycaemic control in Type 2 diabetes, and cardiovascular and renal outcomes. Their widespread use has given rise to concerns regarding rare but potentially serious adverse events.
Peter Ueda
wiley   +1 more source

Thyroid Cancer: Epidemiology, Diagnosis, and Treatment. [PDF]

Dtsch Arztebl Int
Holzer K, Koehler VF, Bojunga J, Luster M, Bartsch DK, Eilsberger F.   +5 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U-87 MG cells. [PDF]

FEBS Open Bio
Gupta P, Furness SG, Gharbi T, De Paoli-Iseppi R, Joshi SS, Clark M, Hare DL, Wookey P.   +7 more
europepmc   +1 more source

Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control

The Journal of Physiology, EarlyView.
Richard J. A. Wilson, Nicholas Jendzjowsky   +1 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, Volume 20, Issue 11, Page 2569-2583, November 2026.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source