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Trigeminovascular Calcitonin Gene-Related Peptide Release and Peripheral Vascular Responses in a Mouse Model of Accelerated Aging: Implications for Migraine

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Al-Hassany L   +6 more
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Calcitonin

Current Medicinal Chemistry, 1999
The peptide calcitonin (CT) was initially discovered in 1962 as a novel hypocalcemic hormone. This hypocalcemic response was principally due to a potent inhibitory action of CT on osteoclast mediated bone resorption and it is this action which underlies its widespread clinical use for the treatment of bone disorders, including Paget's ...
Findlay, D., Sexton, P., Martin, T.
openaire   +3 more sources

Calcitonin

Rheumatic Disease Clinics of North America, 1997
Calcitonin is FDA approved for the treatment of postmenopausal osteoporosis but not for prevention. The preferred delivery system is nasal. Nasal calcitonin is safe and well tolerated. The vertebral fracture efficacy of calcitonin is less robust than the two approved bisphosphonates (alendronate and risedronate) but is similar to raloxifene in the ...
openaire   +7 more sources

Calcitonin and Migraine

Headache: The Journal of Head and Face Pain, 1986
SYNOPSIS A group of 30 patients (12 M ‐ 18 F) suffering from migraine underwent salmon calcitonin therapy for a period of one month. All patients were treated at first for 30 days with vehicle administration in a daily i.m. injection, as a control.
PATTI, Francesco   +5 more
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Calcitonin

Der Schmerz, 1990
A central antinociceptive effect of calcitonin has been well established in animal experiments. Owing to the lack of appropriate studies, however, a final judgement cannot be made regarding the value of calcitonin in pain therapy. Positive clinical experiences have been reported in the following cases.
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Calcitonin and the peptides from the calcitonin gene

Maturitas, 1987
The alpha-calcitonin gene encodes a small family of peptides: calcitonin, katacalcin, and calcitonin gene-related peptide (CGRP). Calcitonin and katacalcin are produced from one precursor and CGRP from another. Calcitonin and katacalcin come mainly from the thyroid, while CGRP is present in both the thyroid and the central nervous system. Calcitonin is
I, MacIntyre   +3 more
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Calcitonin

2003
Mini Review ; There is yet much to learn about the actions and role of CT. It will be important to better understand die physicochemistry of CT-CTR interaction, and the pharmacokinetics of CT, so that small molecule CT-mimetics and more potent, differently delivered, longer acting forms of the molecule can be designed to control bone resorption and ...
Findlay, D., Sexton, P.
openaire   +3 more sources

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