Results 231 to 240 of about 99,464 (305)

Condylar Bone Quality in Growing Children Is Associated With Genetic Polymorphisms in Genes Involved in Calcium and Phosphate Maintenance. [PDF]

open access: yesBiomed Res Int
Küchler EC   +9 more
europepmc   +1 more source

Evaluating FABP5 as a Therapeutic Target for Pain Management

open access: yesEuropean Journal of Pain, Volume 30, Issue 4, April 2026.
ABSTRACT Background and Objective Fatty acid‐binding proteins (FABPs) are intracellular lipid transporters. Pharmacological inhibition of FABP5 is analgesic in preclinical visceral, inflammatory, neuropathic and joint pain models. Genetic knockout or knockdown of FABP5 induces analgesia in select visceral and inflammatory pain models.
William Warren   +4 more
wiley   +1 more source

Is Current Evidence Sufficient to Establish the Efficacy of Botulinum Toxin A in Treating Persistent Dry Eye Disease? A Systematic Review and Meta‐Analysis of Interventional Studies With a Critical Review Using GRADE Tool

open access: yesHealth Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Standard management of dry eye disease (DED) relies on artificial tears, anti‐inflammatory therapy, and punctal occlusion in selected cases. However, some patients continue to report persistent symptoms. The present article reviewed the efficacy of Botulinum Toxin A (BTX‐A) for DED that remained symptomatic after these ...
Mirsaeed Abdollahi   +6 more
wiley   +1 more source

RETRACTED: Mancinelli et al. The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling. <i>Cells</i> 2022, <i>11</i>, 1591. [PDF]

open access: yesCells
Mancinelli R   +17 more
europepmc   +1 more source

The Role and Importance of Procalcitonin (PCT) Testing in Rational Antibiotic Prescribing and Antibiotic Stewardship Programs

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
ABSTRACT Introduction Antibiotic resistance is a critical global health issue, primarily driven by inappropriate antibiotic prescribing. Identifying reliable biomarkers to guide antibiotic use is essential to combat this challenge. Procalcitonin (PCT) testing has emerged as a promising tool for differentiating bacterial infections from non‐bacterial ...
Alireza Abdollahi   +4 more
wiley   +1 more source

Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai   +3 more
wiley   +1 more source

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