Results 51 to 60 of about 101,964 (348)
Calcitonin negative Medullary Thyroid Carcinoma: a challenging diagnosis or a medical dilemma?
BMC Endocrine Disorders, 2019 BackgroundMedullary thyroid carcinoma is a neuroendocrine tumor belonging form a malignant growth of the thyroid parafollicular C-cells, representing from 1 to 10% of all thyroid cancer.
C. Gambardella +12 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study investigates adenomyosis fibrosis in relation to nociceptive nerves. Nociceptive nerve‐secreted CGRP promotes RAMP1hi CD140b+ CD146+ fibroblast differentiation into myofibroblasts through ERK activation, causing severe fibrosis. Rimegepant‐induced CGRP/RAMP1 signaling blockade alleviates fibrosis and restores fertility in a mouse model. This
Zi Ye +11 more
wiley +1 more source
μ‐Opioid Receptor Dynamics in the Parameningeal Tissue During Migraine Attacks
Annals of Neurology, EarlyView.Objective The possible impact of meningeal μ‐opioid receptor (μOR) binding in migraine remains unknown. This study investigated μOR availability in the cranial parameninges involved in migraine initiation via nociceptor activation. Methods We used positron emission tomography with [11C] carfentanil, and measured μOR availability in meninges and ...
Dajung J. Kim +6 more
wiley +1 more source
Exosomes in Intervertebral Disc Regeneration: Roles, Opportunities, and Challenges
Advanced NanoBiomed Research, EarlyView.Factors of Intervertebral Disc Degeneration Extracellular Matrix (ECM) Exosomes and Intervertebral Disc Degeneration (IVDD) Exosome‐Mediated Therapy for IVDD of Different Cell Sources Application of Engineered Exosomes in IVDD Clinical Application of Exosomes in IVDD Treatment Conclusion and Future Perspectives. Intervertebral disc degeneration (IVDD),
Xianglong Zhou +7 more
wiley +1 more source
BIOCHEMICAL MARKERS OF BONE TISSUE METABOLISM INFLUENCE ON VULNERABILITY OF ATHEROSCLEROTIC LESIONS
Российский кардиологический журнал, 2016 Aim. To assess some of biochemical markers of bone tissue metabolism, in vessel wall in males with coronary atherosclerosis; to evaluate the influence of these markers on vulnerability of atherosclerotic lesion and to figure out the specifics of their ...
Ya. N. Polonskaya +5 more
doaj +1 more source
European Thyroid Journal, 2023 Introduction: Serum calcitonin (CT) and carcinoembryonic antigen (CEA) are valuable tumour markers in patients with medullary thyroid carcinoma (MTC). Both markers most often evolve in parallel after treatment.
Stéphane Bardet +3 more
doaj +1 more source
Metabolomic analysis reveals the molecular mechanism related to leg abnormality in broilers
Animal Research and One Health, EarlyView.The graphical abstract shows the principal results of this study. Compared to the leg normal broilers, the serum calcium to phosphorus ratio was extremely decreased in the group with deformed leg bones. Additionally, a total of nine differential metabolites significantly associated with leg abnormalities and serum calcium and phosphorus levels were ...
Jumei Zheng +9 more
wiley +1 more source
Frontiers in Endocrinology, 2022 BackgroundCalcitonin (Ctn) is widely used as a marker in the diagnosis, prognosis, and postoperative follow-up of patients with medullary thyroid carcinoma (MTC).
Zan Jiao +18 more
doaj +1 more source
Frontiers in Endocrinology, 2021 BackgroundSerum calcitonin level is a useful biomarker for predicting primary tumor size, the extent of lymph node, and distant metastasis in patients with medullary thyroid carcinoma (MTC).
Hyunju Park +9 more
doaj +1 more source
Calcitonin gene-related peptide and pain: a systematic review
The Journal of Headache and Pain, 2017 BackgroundCalcitonin gene-related peptide (CGRP) is widely distributed in nociceptive pathways in human peripheral and central nervous system and its receptors are also expressed in pain pathways. CGRP is involved in migraine pathophysiology but its role
Wendy Sophie Schou +4 more
semanticscholar +1 more source