Results 111 to 120 of about 39,277 (265)
JCI Insight, 2020 Atherosclerosis develops preferentially in areas of the arterial system, in which blood flow is disturbed. Exposure of endothelial cells to disturbed flow has been shown to induce inflammatory signaling, including NF-κB activation, which leads to the ...
Akiko Nakayama +9 more
doaj +1 more source
Egg yolk hydrolysate shows moderate impact on osteoporosis in ovariectomized rats
Journal of the Science of Food and Agriculture, EarlyView.Abstract BACKGROUND This study investigated the protective effect of egg yolk hydrolysate (FC) on osteoporosis in ovariectomized (OVX) rats, a well‐established model of postmenopausal bone loss. OVX rats were fed diets supplemented with 0.2% or 1% FC for 13 weeks.
Ilekuttige Priyan Shanura Fernando +4 more
wiley +1 more source
Evolution of secretin family GPCR members in the metazoa
BMC Evolutionary Biology, 2006 Background Comparative approaches using protostome and deuterostome data have greatly contributed to understanding gene function and organismal complexity.
Clark Melody S +4 more
doaj +1 more source
Calcitonin gene-related peptide is a key neurotransmitter in the neuro-immune axis [PDF]
, 2014 The question of how the neural and immune systems interact in host defence is important, integrating a system that senses the whole body with one that protects.
Bakri M. Assas +2 more
core +2 more sources
Can trigeminal sensations impact saltiness perception? A mini‐review
Journal of the Science of Food and Agriculture, EarlyView.Abstract Many food companies have begun to reduce the salt content in their products due to health concerns; however, this reduction in salt content can affect the food's sensory appeal and flavour complexity. Flavour is defined as a combination of odour (i.e., smell), taste (i.e., gustation) and trigeminal sensations (i.e., chemesthesis).
Emily Dolan +2 more
wiley +1 more source
Inhibitory Effect of Chlorpromazine on RANKL-Induced Osteoclastogenesis in Mouse Bone Marrow Cells
Journal of Pharmacological Sciences, 2011 .: Chlorpromazine (CPZ), the first widely used phenothiazine tranquilizer, is shown to inhibit the action of intracellular calmodulin (CaM) and bone resorption in vivo and in vitro.
Hiroharu Kawamura +2 more
doaj +1 more source
Med Research, EarlyView.ABSTRACT Molecular diagnostics have become an important adjunct to ultrasonography and fine‐needle aspiration (FNA) for thyroid nodules, especially in Bethesda III/IV cytology where malignancy risk is uncertain. This narrative review summarizes the diagnostic and prognostic value of key genomic drivers (BRAF V600E, RAS, RET, TERT, and selected fusions)
Guohui Xiao +14 more
wiley +1 more source
Sensory Neuroscience, EarlyView.This schematic highlights GPCRs as the central hub of olfactory signaling in health and disease. The central GPCR shows odorant activation and downstream pathways. Surrounding quadrants illustrate four GPCR‐mediated themes: odor perception and adaptation, mucosal immunity and regeneration, memory consolidation via neural circuits, and GPCR‐related ...
Zishuo Guo +11 more
wiley +1 more source
PLoS ONE, 2012 Adrenomedullin (AM) and its receptor complexes, calcitonin receptor-like receptor (Calcrl) and receptor activity modifying protein 2/3, are highly expressed in lymphatic endothelial cells and are required for embryonic lymphatic development. To determine
Samantha L Hoopes +2 more
doaj +1 more source
Retention of differentiated properties in an established dog kidney epithelial cell line (MDCK). [PDF]
, 1979 Madin-Darby canine kidney (MDCK) cells grown in tissue culture have the morphological properties of distal tubular epithelial cells, form tight junctions, and lack several proximal tubular enzyme markers.
Chuman, LM +3 more
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