Results 31 to 40 of about 39,277 (265)
CAPA neuropeptides and their receptor form an anti-diuretic hormone signalling system in the human disease vector, Aedes aegypti [PDF]
Insect CAPA neuropeptides are homologs of mammalian neuromedin U and are known to influence ion and water balance by regulating the activity of the Malpighian ‘renal’ tubules (MTs).
Ber, Lindsay Taylor +7 more
core +1 more source
BackgroundAdrenomedullin 2 (ADM2), adrenomedullin (ADM), and calcitonin gene-related peptides (α- and β-CGRPs) signal through heterodimeric calcitonin receptor-like receptor/receptor activity-modifying protein 1, 2 and 3 (CLR/RAMP1, 2 and 3) complexes ...
Chia Lin Chang +4 more
doaj +1 more source
Calcitonin receptor-like receptor is expressed on gastrointestinal immune cells [PDF]
Background/Aims: Pharmacological and morphological studies suggest that the gut mucosal immune system and local neuropeptide-containing neurones interact.
Göke, B. +5 more
core +1 more source
Calcitonin/Amylin Receptors and Ramps
Our understanding of G protein-coupled receptor function has recently expanded to encompass novel protein interactions that underlie both cell surface receptor expression and the exhibited phenotype. The most notable examples are those involving receptor
Patrick M. Sexton
doaj +1 more source
Calcitonin gene-related peptide (CGRP) is one of the most potent microvascular vasodilators identified to date. Vascular relaxation and vasodilation is mediated via activation of the CGRP receptor.
Stelios eKokkoris +2 more
doaj +1 more source
Cerebellar distribution of calcitonin gene-related peptide (CGRP) and its receptor components calcitonin receptor-like receptor (CLR) and receptor activity modifying protein 1 (RAMP1) in rat [PDF]
Clinical and experimental results have revealed a fundamental role of calcitonin gene-related peptide (CGRP) in primary headaches. CGRP is widely expressed in neurons both in the central nervous system (CNS) and in peripheral sensory nerves. In the CNS there is a wide distribution of CGRP-containing neurons with the highest levels seen in striatum ...
Edvinsson, Lars +3 more
openaire +3 more sources
Triptans and CGRP blockade - impact on the cranial vasculature [PDF]
The trigeminovascular system plays a key role in the pathophysiology of migraine. The activation of the trigeminovascular system causes release of various neurotransmitters and neuropeptides, including serotonin and calcitonin gene-related peptide ...
Alejandro Labastida-Ramírez +9 more
core +3 more sources
CGRP Receptor Family and Accessory Protein Localization: Implications for Predicted Function
Calcitonin gene-related peptide (CGRP), adrenomedullin, amylin, and calcitonin are functionally related neuropeptides. Certain of these peptides mediate their action through receptors which have common components, such as the receptor activity modifying ...
K.R. Oliver
doaj +1 more source
Protein Transduction Method for Cerebrovascular Disorders [PDF]
Many studies have shown that a motif of 11 consecutive arginines (11R) is one of the most effective protein transduction domains (PTD) for introducing proteins into the cell membrane.
Arimitsu, Seiji +9 more
core +1 more source
Differential glycosylation of human and rat (r) calcitonin (CT) receptor‐like receptors (CRLR) as a result of interactions with accessory receptor activity‐modifying proteins (RAMP)1 or ‐2 was considered to define CT gene‐related peptide (CGRP) or adrenomedullin (ADM) receptors in mammalian cells.
Aldecoa, Amaya +3 more
openaire +2 more sources

