Results 101 to 110 of about 49,400 (296)
Strong additive effect of 1,25-dihydroxycholecalciferol and cyclosporine A but not tacrolimus in rat lung allotransplantation [PDF]
, 2017 Objectives: 1,25-Dihydroxycholecalciferol (calcitriol, vitamin D3) has immunosuppressive properties. This study evaluates the effect of calcitriol in combination with either cyclosporine A or tacrolimus on acute lung allograft rejection in a rat model of
Ayuni, Erick +6 more
core
Thyroxine-binding globulin: investigation of microheterogeneity [PDF]
, 1981 Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland +4 more
core +1 more source
Experimental Physiology, EarlyView.Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu +4 more
wiley +1 more source
Pharmaceutical Biology, 2020 Context Airway remodelling is one of the most refractory problems in asthma. According to the critical roles of oxidative stress and inflammation in airway remodelling, it is supposed that ascorbic acid and calcitriol have beneficial effects.
Farzaneh Kianian +5 more
doaj +1 more source
Association of Anabolic Effect of Calcitriol with Osteoclast-Derived Wnt 10b Secretion
Nutrients, 2018 Canonical Wnt (Wingless/Integrated) signaling is crucial in bone development and the Wnt ligand can promote osteoblast differentiation from mesenchymal progenitor cells.
Chien-Lin Lu +9 more
semanticscholar +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend AC: adenylyl cyclase, APT: adenosine triphosphate, AMP: adenosine monophosphate, cAMP: cyclic adenosine monophosphate, PDE: phosphodiesterase, PKA: protein kinase A, PPT: protein phosphatase, P: phosphorylation, RyR: ryanodine receptor, SERCA: sarcoplasmic/endoplasmic reticulum Ca2+‐adenosine triphosphatase, SR: sarcoplasmic ...
Moritz Linder +4 more
wiley +1 more source
PTH suppression by calcitriol does not predict off‐target actions in experimental CKD
Pharmacology Research & Perspectives, 2020 Vitamin D receptor agonist (VDRA) therapy for PTH suppression is a mainstay for patients with severe CKD. Calcitriol (1,25‐(OH)2D3) is a former first‐line VDRA in CKD treatment.
Bruno A. Svajger +8 more
doaj +1 more source
Journal of Pharmacology and Experimental Therapeutics, 2018 Patients with chronic kidney disease (CKD) have a markedly increased risk for developing cardiovascular disease. Nontraditional risk factors, such as increased phosphate retention, increased serum fibroblast growth factor 23 (FGF-23), and deficiencies in
Kristin M. McCabe +8 more
semanticscholar +1 more source
Effect of calcitriol supplementation and tail suspension on serum biomarkers of bone formation in rats [PDF]
, 2015 BACKGROUND: Calcitriol is documented to cause significant increase in bone mass densitometry counteracting osteoporosis. Promising results of calcitriol supplementation in studies aiming space flight induced osteoporosis is little and the effect of this ...
Amir Khoshvaghti +4 more
core +1 more source
Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.GRAPHICAL ABSTRACT 1. Vitamin D reduced in platelet count. 2. Vitamin D increased in MPV levels. Abstract Vitamin D has well‐documented antithrombotic effects on coagulation system components, and platelet‐associated vitamin D receptors (VDR) play an important role.
Pardis Daneshpour +3 more
wiley +1 more source