Results 11 to 20 of about 42,581 (243)

A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C [PDF]

, 2012
Background: To perform a comprehensive study on the relationship between vitamin D metabolism and the response to interferon-α-based therapy of chronic hepatitis C.
Badenhoop, Klaus, Berg, Thomas, Bibert, Stephanie, Bochud, Pierre-Yves, Bojunga, Jörg, Burgisser, Philippe, Cerny, Andreas, Dufour, Jean-François, Geier, Andreas, Gerlach, Tilman J, Heim, Markus H, Kutalik, Zoltan, Lange, Christian M, Malinverni, Raffaele, Moradpour, Darius, Müller, Tobias, Negro, Francesco, Regenass, Stephan, Sarrazin, Christoph, Swiss Hepatitis C Cohort Study Group,, Zeuzem, Stefan   +20 more
core   +10 more sources

Association of High Calcitriol Serum Levels and Its Hydroxylation Efficiency Ratio with Disease Risk in SLE Patients with Vitamin D Deficiency

Journal of Immunology Research, 2021
Vitamin D (calcidiol) deficiency in systemic lupus erythematosus (SLE) is more frequent than in healthy subjects (HS); it is associated with clinical activity and damage in SLE.
Mónica R. Meza-Meza, José Francisco Muñoz-Valle, Adolfo I. Ruiz-Ballesteros, Barbara Vizmanos-Lamotte, Isela Parra-Rojas, Erika Martínez-López, Edith Oregon-Romero, Yolanda Fabiola Márquez-Sandoval, Sergio Cerpa-Cruz, Ulises de la Cruz-Mosso   +9 more
doaj   +1 more source

Analysis of the interaction of calcitriol with the disulfide isomerase ERp57 [PDF]

, 2016
Calcitriol, the active form of vitamin D3, can regulate the gene expression through the binding to the nuclear receptor VDR, but it can also display nongenomic actions, acting through a membrane- associated receptor, which has been discovered as the ...
Altieri, Fabio, Cervoni, Laura, Chichiarelli, Silvia, Eufemi, Margherita, Gaucci, Elisa, Grillo, Caterina, Nittari, Giulio, Raimondo, Domenico   +7 more
core   +1 more source

Calcitriol-enhanced autophagy in gingival epithelium attenuates periodontal inflammation in rats with type 2 diabetes mellitus

Frontiers in Endocrinology, 2023
Type 2 diabetes mellitus (T2DM)-associated periodontitis is a common disease with high prevalence, associated with persistent infection and complicated manifestations.
Yanan Wang, Maoting Huang, Wanlin Xu, Fulong Li, Chunliang Ma, Xiaolin Tang   +5 more
doaj   +1 more source

A novel model to explain dietary factors affecting hypocalcaemia in dairy cattle [PDF]

, 2011
Most dairy cows exhibit different degrees of hypocalcaemia around calving because the gestational Ca requirements shift to the disproportionately high Ca requirements of lactation.
Martin-Tereso Lopez, J., Verstegen, M.W.A.   +1 more
core   +2 more sources

Calcitriol confers neuroprotective effects in traumatic brain injury by activating Nrf2 signaling through an autophagy-mediated mechanism

Molecular Medicine, 2021
Background The present study aimed to further explore the potential interaction between oxidative stress and autophagy in the progression of traumatic brain injury (TBI) and therapeutic mechanism of calcitriol, the active form of vitamin D (VitD ...
Changmeng Cui, Changshui Wang, Feng Jin, Mengqi Yang, Lingsheng Kong, Wenxiu Han, Pei Jiang   +6 more
doaj   +1 more source

Synthesis of 1 alpha,25-Dihydroxyvitamin D Analogues Featuring a S-2-symmetric CD-ring Core [PDF]

, 2009
Three analogues of 1 alpha,25-dihydroxyvitamin D-3 (calcitriol), featuring a transfused decalin C, D-core with local S-2-symmetry, and possessing identical side-chain and seco-B,A-ring structures, have been synthesized starting from readily available ...
De Clercq, Pierre, Minne, Garrett
core   +2 more sources

Induction of the Vitamin D Receptor Attenuates Autophagy Dysfunction-Mediated Cell Death Following Traumatic Brain Injury

Cellular Physiology and Biochemistry, 2017
Background/Aims: Traumatic brain injury (TBI) is a major public health problem in the world and causes high rates of mortality and disability. Recent evidence suggests that vitamin D (VD) has neuroprotective actions and can promote function recovery ...
Changmeng Cui, Jianzhong Cui, Feng Jin, Ying Cui, Ran Li, Xiaohua Jiang, Yanxia Tian, Kaijie Wang, Pei Jiang, Junling Gao   +9 more
doaj   +1 more source

Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis [PDF]

, 2006
BACKGROUND: Treatment with glucocorticoids is associated with bone loss starting soon after therapy is initiated and an increased risk of fracture. METHODS: We performed a randomized, double-placebo, double-blind clinical trial of 18 months' duration ...
Ale Algra, Anne-Margriet Huisman, Ans C.M. Oostveen, Ben A.C. Dijkmans, Chris E.D. de Laet, de Nijs RN, Erik Buskens, George A.W. Bruyn, Johannes W.G. Jacobs, Johannes W.J. Bijlsma, Michel BA, Piet P.M.M. Geusens, Roland F.J. Laan, Ron N.J. de Nijs, Willem F. Lems   +14 more
core   +4 more sources

RETRACTED: Progesterone-Calcitriol Combination Enhanced Cytotoxicity of Cisplatin in Ovarian and Endometrial Cancer Cells In Vitro

Biomedicines, 2020
Initially, patients that respond to cisplatin (DDP) treatment later relapse and develop chemoresistance. Agents that enhance DDP effectiveness will have a significant impact on cancer treatment.
Ana Paucarmayta, Hannah Taitz, Latoya McGlorthan, Yovanni Casablanca, G. Larry Maxwell, Kathleen M. Darcy, Viqar Syed   +6 more
doaj   +1 more source