Results 31 to 40 of about 25,694 (210)
Calcitriol enhances pyrazinamide treatment of murine tuberculosis
Chinese Medical Journal, 2019 . Background:. Tuberculosis is a leading cause of morbidity and mortality in humans worldwide. There is an urgent need for new and effective drugs to treat tuberculosis and shorten the duration of tuberculosis therapy.
Jing Zhang +8 more
doaj +1 more source
International Journal of Immunopathology and PharmacologyDespite being one of the most frequently used chemotherapy agents, cisplatin exhibits substantial hepatorenal injury by triggering oxidative stress, inflammation, and apoptosis pathways.
Mohamed A Morsy +4 more
doaj +1 more source
Angewandte Chemie, EarlyView.Vitamin D entfaltet über die Aktivierung des ligandenabhängigen Transkriptionsfaktors Vitamin‐D‐Rezeptor (VDR) komplexe und zellspezifische biologische Wirkungen in verschiedenen Geweben. Das photoschaltbare Vitamin‐D‐Mimetikum 10 wechselt durch Belichtung zwischen VDR‐Antagonisten‐ (E) und Agonisten‐Aktivität (Z) und bietet eine bislang einzigartige ...
Xiu Ge +11 more
wiley +1 more source
, 2017 Introducción: El calcitriol, fundamental para mantener la homeostasis del calcio y el fósforo en el organismo, puede perjudicar al sistema vascular a dosis elevadas, aumentando el riesgo de calcificación.
Tuñón LePoultel D +5 more
core +1 more source
Angewandte Chemie International Edition, EarlyView.Vitamin D exhibits complex and cell‐specific biological effects in multiple tissues via activation of the ligand‐sensing transcription factor vitamin D receptor (VDR). The photo‐switchable vitamin D mimetic 10 transitions between VDR antagonist (E) and agonist (Z) activity upon illumination and offers unprecedented bidirectional optical control over ...
Xiu Ge +11 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Background CD4 T cells specific for citrullinated (cit)‐peptides are key players in RA immunopathogenesis. Characterising these cells and identifying features of healthy and RA‐associated autoreactivity will provide valuable insight into disease mechanisms and form the basis of immune state biomarkers to facilitate the next generation of RA treatments.
James A. Stanway +13 more
wiley +1 more source
PLoS ONE, 2014 The active metabolite of vitamin D3, 1,25-dihydroxyvitamin D3 (calcitriol) has antiproliferative effects in non-aggressive prostate cancer, however, its effects in more aggressive model systems are still unclear.
Adebusola Alagbala Ajibade +7 more
doaj +1 more source
Biotropic: The Journal of Tropical Biology, 2021 The health impact for active and passive smokers is damage to the organs and respiratory tract. The body organs initially experience inflammation which increases the number of white blood cells, one of which is an increase in lymphocytes.
Jordy Oktobiannobel +3 more
doaj +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Phytotherapy Research, EarlyView.Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Calcitriol Overloaded Lymphocytes (COLs)
, 2013 Levels of calcitriol in calcitriol overloaded lymphocyte (COLs) lysates and control lymphocytes. Values expressed as mean + SEM (n=3) * P
Imrana Naseem (167034) +2 more
core +1 more source