Results 51 to 60 of about 25,694 (210)

Topical Calcitriol is Degraded by Ultraviolet Light

open access: yes, 2003
Calcitriol ointment has been approved for the treatment of psoriasis in many countries around the world. It may be prescribed in conjunction with phototherapy.
Gilliard, Jean   +4 more
core   +1 more source

Effect of Two Therapeutic Renal Diets on Hormonal and Regulatory Pathways Affecting Calcium Homeostasis in Cats With Early‐Stage Chronic Kidney Disease

open access: yesJournal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Chronic kidney disease (CKD) is a known risk factor for hypercalcemia in cats. Phosphate‐restricted diets have also been implicated in causing hypercalcemia, in part because phosphate restriction increases the Ca:P ratio. The primary objective of this study was to evaluate the impact of two different therapeutic renal foods on ionized (iCa ...
Jean A. Hall   +4 more
wiley   +1 more source

Relationship between calcitriol and GDNF signaling.

open access: yes, 2013
The beneficial effect of calcitriol addition to media was shown to be a result of increased GDNF. (A, B) 10 nM calcitriol added to media caused almost a 1.8-fold increase in GDNF expression, observed by Western blotting. GAPDH was used as loading control;
Manminder S. Bhangal (405956)   +2 more
core   +1 more source

Calcitriol downregulates fibroblast growth factor receptor 1 through histone deacetylase activation in HL-1 atrial myocytes

open access: yesJournal of Biomedical Science, 2018
Background Fibroblast growth factor (FGF)-2 plays a crucial role in the pathophysiology of cardiovascular diseases (CVDs). FGF-2 was reported to induce cardiac hypertrophy through activation of FGF receptor 1 (FGFR1).
Ting-Wei Lee   +4 more
doaj   +1 more source

Relationship between vitamin D deficiency and early implant failure and osseointegration

open access: yesPeriodontology 2000, EarlyView.
Abstract Background This systematic review investigated the relationship between pre‐operative vitamin D levels and implant osseointegration and implant‐related outcomes. It also assessed studies involving vitamin D supplementation before implant placement.
Richard J. Miron   +8 more
wiley   +1 more source

Factors influencing calcitriol metabolism in renal failure

open access: yes, 1990
Factors influencing calcitriol metabolism in renal failure. Metabolic clearance rate (MCR) and production rate (PR) of calcitriol is decreased in experimental renal failure.
Patel, Sanjeev, Hsu, Chen H.
core   +1 more source

Experimental Approach for Drug Profiling of Calcitriol in Yeast

open access: yes, 2016
Vitamin D regulation is associated with several human disorders and contributes to various cellular mechanisms. Calcitriol (commercially available as Rocaltrol), an active Vitamin D metabolite, is known as a neuro-protective and anti-cancer drug but most
Jagadeesan, Sasi Kumar
core   +2 more sources

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

open access: yesExperimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu   +4 more
wiley   +1 more source

CYP24A1 Inhibition Enhances the Antitumor Activity of Calcitriol

open access: yes, 2010
High systemic exposures to calcitriol are necessary for optimal antitumor effects. Human prostate cancer PC3 cells are insensitive to calcitriol treatment.
Kristie L. Engler   +6 more
core   +1 more source

Focus on 1,25-Dihydroxyvitamin D3 in the Peripheral Nervous System

open access: yesFrontiers in Neuroscience, 2019
In this review, we draw attention to the roles of calcitriol (1,25-dihydroxyvitamin D3) in the trophicity of the peripheral nervous system. Calcitriol has long been known to be crucial in phosphocalcium homeostasis. However, recent discoveries concerning
Pierre Antoine Faye   +11 more
doaj   +1 more source

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