Results 61 to 70 of about 21,845 (162)

Calcitriol Inhibits HCV Infection via Blockade of Activation of PPAR and Interference with Endoplasmic Reticulum-Associated Degradation

Viruses, 2018
Vitamin D has been identified as an innate anti-hepatitis C virus (HCV) agent but the possible mechanisms for this issue remain unclear. Here, we clarified the mechanisms of calcitriol-mediated inhibition of HCV infection.
Yu-Min Lin, Hung-Yu Sun, Wen-Tai Chiu, Hui-Chen Su, Yu-Chieh Chien, Lee-Won Chong, Hung-Chuen Chang, Chyi-Huey Bai, Kung-Chia Young, Chiung-Wen Tsao   +9 more
doaj   +1 more source

Calcitriol is involved in maintaining primordial follicle reserve through the inhibition of the PI3K/Akt signaling pathway

Journal of Ovarian Research
Background In mammals, precise regulation of primordial follicle activation is essential for maintaining the female reproductive lifespan. In this study, we demonstrated that the vitamin D receptor (VDR) is expressed in both pre-granulosa cells and ...
Shuang Liu, Ye Chen, Hongwei Wei, Huiyu Liu, Weiyong Wang, Yanli Sun, Luchun Zhang, Sihui He, Xiaodan Zhang, Jingjie Li, Meijia Zhang   +10 more
doaj   +1 more source

Preclinical Prevention Trial of Calcitriol: Impact of Stage of Intervention and Duration of Treatment on Oral Carcinogenesis

Neoplasia: An International Journal for Oncology Research, 2019
The anticancer activity of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3 or calcitriol) has been widely reported in preclinical models. However, systematic investigation into the chemopreventive potential of calcitriol against the spectrum of oral carcinogenesis
Vui King Vincent-Chong, Hendrik DeJong, Kristopher Attwood, Pamela A. Hershberger, Mukund Seshadri   +4 more
doaj   +1 more source

Effect of exogenous calcitriol on myopia development and axial length in guinea pigs with form deprivation myopia

Scientific Reports
The annual increase in myopia prevalence poses a significant economic and health challenge. Our study investigated the effect of calcitriol role in myopia by inducing the condition in guinea pigs through form deprivation for four weeks.
Rongbin Liang, Wenqing Shi, Tao Li, Hui Gao, Ting Wan, Bing Li, Xiaodong Zhou   +6 more
doaj   +1 more source

Calcitriol modulates the effects of bone marrow-derived mesenchymal stem cells on macrophage functions [PDF]

Iranian Journal of Basic Medical Sciences, 2015
Objective(s):Some evidence showed that calcitriol has an important role in regulating growth and differentiation of mesenchymal stem cells (MSCs). However, the interaction between mesenchymal stem cells and macrophage is not clear yet.  The current study
Bahman Mansouri Motlagh, Nahideh Afzale Ahangaran, Seyyed Meysam Abtahi Froushani   +2 more
doaj  

Dietary supplementation with calcitriol or quercetin improved eggshell and bone quality by modulating calcium metabolism

Animal Nutrition
This study was aimed to investigate the effects of dietary calcitriol or quercetin supplementation on eggshell and bone quality of laying hens. In trial 1, 72 Hy-Line Brown layers (80-week-old) with weak-shelled strength (25 to 30 N) were assigned into 4
Yu Fu, Jianmin Zhou, Martine Schroyen, Jing Lin, Haijun Zhang, Shugeng Wu, Guanghai Qi, Jing Wang   +7 more
doaj   +1 more source

Management of osteoporosis with calcitriol in elderly Chinese patients: a systematic review

Clinical Interventions in Aging, 2014
Ruo-xi Liao, Miao Yu, Yan Jiang, Weibo XiaDepartment of Endocrinology, Key Laboratory of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, and Chinese Academy of Medical Sciences, Beijing, People's Republic of ChinaAbstract ...
Liao RX, Yu M, Jiang Y, Xia WB
doaj  

Transcriptomic profile induced by calcitriol in CaSki human cervical cancer cell line.

PLoS ONE
The vitamin D endocrine system, primarily mediated by its main metabolite calcitriol and the vitamin D receptor (VDR), plays a critical role in numerous human physiological processes, ranging from calcium metabolism to the prevention of various tumors ...
Euclides Avila, Luis David Hernández-Monterde, Alberto Cedro-Tanda, Tomas Misael Lizardi-Aguilera, David Barrera, Francisco Vladimir Villegas-Rodriguez, Janice García-Quiroz, Lorenza Díaz, Fernando Larrea   +8 more
doaj   +1 more source

Inmunoregulación mediada por Calcitriol

Revista de la Facultad de Medicina, 2000
El papel clásico endocrino del calcitriol (la, 25-dihidroxivitamina D3) en la homeóstasis del calcio es bien conocido. Los hallazgos relativamente recientes de la presencia del receptor de calcitriol en monocitos, linfocitos y diversas líneas celulares,
Alberto Pinzón, Adriana Bermeo, Jean Paul Vernot   +2 more
doaj  

The potential of calcitriol gel in accelerating the healing of traumatic oral ulcers. [PDF]

J Taibah Univ Med Sci
Radithia D, Ernawati DS, Ayuningtyas NF, Mahdani FY, Parmadiati AE, Pratiwi AS, Sarasati A, Bakti RK, Fatarnaha NT, Fitri AR, Rachmadanti ZK, Datau MA, Rokhani FB.   +12 more
europepmc   +1 more source