Results 11 to 20 of about 25,694 (210)

Budesonide and Calcitriol Synergistically Inhibit Airway Remodeling in Asthmatic Mice

Canadian Respiratory Journal, 2018
Background and Objective. While calcitriol can inhibit airway remodeling in asthmatic mice, the mechanism remains unclear. The purpose of this study was to explore the mechanism of action of calcitriol on airway remodeling in asthma and its interaction ...
Jun Qian, Yaqin Xu, Zhiwei Yu
doaj   +3 more sources

Immunomodulatory mechanisms of action of calcitriol in psoriasis

Indian Journal of Dermatology, 2014
Background: Calcitriol is well known for its therapeutic efficacy in psoriasis, but its mechanism of action is still unclear. In this study, we tried to elucidate the precise mechanism of calcitriol for its therapeutic efficacy in psoriasis.
Suravi Raychaudhuri, Anupam Mitra, Ananya Datta-Mitra   +2 more
doaj   +2 more sources

Management of osteoporosis with calcitriol in elderly Chinese patients: a systematic review

Clinical Interventions in Aging, 2014
Ruo-xi Liao, Miao Yu, Yan Jiang, Weibo XiaDepartment of Endocrinology, Key Laboratory of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, and Chinese Academy of Medical Sciences, Beijing, People's Republic of ChinaAbstract ...
Liao RX, Yu M, Jiang Y, Xia WB
doaj   +1 more source

Inmunoregulación mediada por Calcitriol

Revista de la Facultad de Medicina, 2000
El papel clásico endocrino del calcitriol (la, 25-dihidroxivitamina D3) en la homeóstasis del calcio es bien conocido. Los hallazgos relativamente recientes de la presencia del receptor de calcitriol en monocitos, linfocitos y diversas líneas celulares,
Alberto Pinzón, Adriana Bermeo, Jean Paul Vernot   +2 more
doaj   +1 more source

Calcitriol-Loaded Multifunctional Nanospheres with Superlubricity for Advanced Osteoarthritis Treatment

, 2023
Osteoarthritis (OA) is characterized by the lubrication dysfunction of a cartilage sliding interface caused by chronic joint inflammation, and effective nonsurgical therapy for advanced OA remains lacking.
Huiwen Lu (16383797), Wenhua Li (426756), Chao Xie (524756), Yu Dong (398252), Zhanpeng Liu (16383803), Jinhao Cheng (16383800), Lijun Lin (289688), Qili Sun (15265256), Zhaowei Lin (6018188), Kai Li (205203), Jie Qi (53195), Bin Tang (56654)   +11 more
core   +3 more sources

Calcitriol imparts neuroprotection in vitro to midbrain dopaminergic neurons by upregulating GDNF expression [PDF]

, 2013
During development a tightly controlled signaling cascade dictates the differentiation, maturation and survival of developing neurons. Understanding this signaling mechanism is important for developing therapies for neurodegenerative illnesses.
Ormerod
core   +3 more sources

Association of High Calcitriol Serum Levels and Its Hydroxylation Efficiency Ratio with Disease Risk in SLE Patients with Vitamin D Deficiency

Journal of Immunology Research, 2021
Vitamin D (calcidiol) deficiency in systemic lupus erythematosus (SLE) is more frequent than in healthy subjects (HS); it is associated with clinical activity and damage in SLE.
Mónica R. Meza-Meza, José Francisco Muñoz-Valle, Adolfo I. Ruiz-Ballesteros, Barbara Vizmanos-Lamotte, Isela Parra-Rojas, Erika Martínez-López, Edith Oregon-Romero, Yolanda Fabiola Márquez-Sandoval, Sergio Cerpa-Cruz, Ulises de la Cruz-Mosso   +9 more
doaj   +1 more source

RETRACTED: Progesterone-Calcitriol Combination Enhanced Cytotoxicity of Cisplatin in Ovarian and Endometrial Cancer Cells In Vitro

Biomedicines, 2020
Initially, patients that respond to cisplatin (DDP) treatment later relapse and develop chemoresistance. Agents that enhance DDP effectiveness will have a significant impact on cancer treatment.
Ana Paucarmayta, Hannah Taitz, Latoya McGlorthan, Yovanni Casablanca, G. Larry Maxwell, Kathleen M. Darcy, Viqar Syed   +6 more
doaj   +1 more source

Calcitriol confers neuroprotective effects in traumatic brain injury by activating Nrf2 signaling through an autophagy-mediated mechanism

Molecular Medicine, 2021
Background The present study aimed to further explore the potential interaction between oxidative stress and autophagy in the progression of traumatic brain injury (TBI) and therapeutic mechanism of calcitriol, the active form of vitamin D (VitD ...
Changmeng Cui, Changshui Wang, Feng Jin, Mengqi Yang, Lingsheng Kong, Wenxiu Han, Pei Jiang   +6 more
doaj   +1 more source

Calcitriol-enhanced autophagy in gingival epithelium attenuates periodontal inflammation in rats with type 2 diabetes mellitus

Frontiers in Endocrinology, 2023
Type 2 diabetes mellitus (T2DM)-associated periodontitis is a common disease with high prevalence, associated with persistent infection and complicated manifestations.
Yanan Wang, Maoting Huang, Wanlin Xu, Fulong Li, Chunliang Ma, Xiaolin Tang   +5 more
doaj   +1 more source