Comparison of VILIP-1 and VILIP-3 binding to phospholipid monolayers.
PLoS ONE, 2014 The neuronal calcium sensor proteins Visinin-like Proteins 1 (VILIP-1) and 3 (VILIP-3) are effectors of guanylyl cyclase and acetyl choline receptors, and transduce calcium signals in the brain.
Samuel Rebaud +6 more
doaj +1 more source
S100 Proteins—Intracellular and Extracellular Function in Norm and Pathology
BiomoleculesThe S100 proteins are small, ubiquitous, mostly homodimeric proteins containing two EF-hand structures, that is, helix-loop-helix motifs specialized in high-affinity calcium-binding (~10−6 M) [...]
Wiesława Leśniak, Anna Filipek
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In silico prediction and analysis of Caenorhabditis EF-hand containing proteins. [PDF]
PLoS ONE, 2012 Calcium (Ca⁺²) is a ubiquitous messenger in eukaryotes including Caenorhabditis. Ca⁺²-mediated signalling processes are usually carried out through well characterized proteins like calmodulin (CaM) and other Ca⁺² binding proteins (CaBP).
Manish Kumar +4 more
doaj +1 more source
Use of top-down and bottom-up fourier transform ion cyclotron resonance mass spectrometry for mapping calmodulin sites modified by platinum anticancer drugs [PDF]
, 2011 Calmodulin (CaM) is a highly conserved, ubiquitous, calcium-binding protein; it binds to and regulates many different protein targets, thereby functioning as a calcium sensor and signal transducer.
Lin, Tzu-Yung +17 more
core +1 more source
Dynamics and Epigenetics of the Epidermal Differentiation Complex
EpigenomesEpidermis is the outer skin layer built of specialized cells called keratinocytes. Keratinocytes undergo a unique differentiation process, also known as cornification, during which their gene expression pattern, morphology and other properties change ...
Wiesława Leśniak
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Two structural motifs within canonical EF-hand calcium-binding domains identify five different classes of calcium buffers and sensors. [PDF]
PLoS ONE, 2014 Proteins with EF-hand calcium-binding motifs are essential for many cellular processes, but are also associated with cancer, autism, cardiac arrhythmias, and Alzheimer's, skeletal muscle and neuronal diseases.
Konstantin Denessiouk +4 more
doaj +1 more source
Biomolecules, 2022 Neuronal calcium sensors (NCSs) are the family of EF-hand proteins mediating Ca2+-dependent signaling pathways in healthy neurons and neurodegenerative diseases.
Viktoriia E. Baksheeva +8 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Characterization of XVEF and XvCaM : two calcium-binding proteins isolated from the resurrection plant Xerophyta viscosa [PDF]
, 2005 Includes bibliographical references.Xerophyta viscosa (Baker) is a resurrection plant with the ability to survive desiccation and rehydrate upon watering with minimal tissue damage.
Conrad, Nailah
core
Identification of bovine brain calcium binding proteins [PDF]
, 1987 Three peaks of calcium binding activity have been identified by the Chelex-100 calcium binding assay of the fractions from DEAE cellulose chromatography of 100,000 × g supernatant of bovine brain.
Tokuda, Masaaki +2 more
core +1 more source