Results 41 to 50 of about 3,615,813 (279)
An Update to Calcium Binding Proteins
, 2019 Ca2+ binding proteins (CBP) are of key importance for calcium to play its role as a pivotal second messenger. CBP bind Ca2+ in specific domains, contributing to the regulation of its concentration at the cytosol and intracellular stores. They also participate in numerous cellular functions by acting as Ca2+ transporters across cell membranes or as Ca2+-
Jacobo Elíes +5 more
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Comparison of VILIP-1 and VILIP-3 binding to phospholipid monolayers.
PLoS ONE, 2014 The neuronal calcium sensor proteins Visinin-like Proteins 1 (VILIP-1) and 3 (VILIP-3) are effectors of guanylyl cyclase and acetyl choline receptors, and transduce calcium signals in the brain.
Samuel Rebaud +6 more
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Calcium‐binding proteins in rat skin
FEBS Letters, 1987 Skin Ca2+‐binding protein (SCaBP) was reported to be distinct from the Ca2+‐binding parvalbumin (PV), however, more recently its amino acid sequence was shown to be identical to PV. We purified a protein (Mr12 000; pI4.5) from isolated epidermis (free of other cell layers) of adult rats and whole skin (containing no PV) of newborn rats. This protein is
Schelling, Claude P. +5 more
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S100 Proteins—Intracellular and Extracellular Function in Norm and Pathology
BiomoleculesThe S100 proteins are small, ubiquitous, mostly homodimeric proteins containing two EF-hand structures, that is, helix-loop-helix motifs specialized in high-affinity calcium-binding (~10−6 M) [...]
Wiesława Leśniak, Anna Filipek
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In silico prediction and analysis of Caenorhabditis EF-hand containing proteins. [PDF]
PLoS ONE, 2012 Calcium (Ca⁺²) is a ubiquitous messenger in eukaryotes including Caenorhabditis. Ca⁺²-mediated signalling processes are usually carried out through well characterized proteins like calmodulin (CaM) and other Ca⁺² binding proteins (CaBP).
Manish Kumar +4 more
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s-cyclophilin is retained intracellularly via a unique COOH-terminal sequence and colocalizes with the calcium storage protein calreticulin [PDF]
, 1992 Cyclophilins (cyclosporin A-binding proteins) are conserved, ubiquitous, and abundant proteins that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins in vitro.
Arber, S. +6 more
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Identification of Structural Calcium Binding Sites in Membrane-Bound Presenilin 1 and 2
, 2020 Variants of presenilin (PS1 and PS2) are the main genetic risk factors of familial Alzheimer's disease and thus central to the disease etiology. Although mostly studied as catalytic units of γ-secretase controlling Aβ production, presenilins also affect ...
Mehra, Rukmankesh +1 more
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Dynamics and Epigenetics of the Epidermal Differentiation Complex
EpigenomesEpidermis is the outer skin layer built of specialized cells called keratinocytes. Keratinocytes undergo a unique differentiation process, also known as cornification, during which their gene expression pattern, morphology and other properties change ...
Wiesława Leśniak
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Two structural motifs within canonical EF-hand calcium-binding domains identify five different classes of calcium buffers and sensors. [PDF]
PLoS ONE, 2014 Proteins with EF-hand calcium-binding motifs are essential for many cellular processes, but are also associated with cancer, autism, cardiac arrhythmias, and Alzheimer's, skeletal muscle and neuronal diseases.
Konstantin Denessiouk +4 more
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Biomolecules, 2022 Neuronal calcium sensors (NCSs) are the family of EF-hand proteins mediating Ca2+-dependent signaling pathways in healthy neurons and neurodegenerative diseases.
Viktoriia E. Baksheeva +8 more
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