Results 31 to 40 of about 739,758 (297)

Coarse-Grained Modeling and Molecular Dynamics Simulations of Ca2+-Calmodulin

Frontiers in Molecular Biosciences, 2021
Calmodulin (CaM) is a calcium-binding protein that transduces signals to downstream proteins through target binding upon calcium binding in a time-dependent manner.
Jules Nde, Jules Nde, Pengzhi Zhang, Jacob C. Ezerski, Wei Lu, Kaitlin Knapp, Peter G. Wolynes, Margaret S. Cheung, Margaret S. Cheung   +8 more
doaj   +1 more source

Junctate is a key element in calcium entry induced by activation of InsP3 receptors and/or calcium store depletion [PDF]

, 2004
In many cell types agonist-receptor activation leads to a rapid and transient release of Ca(2+) from intracellular stores via activation of inositol 1,4,5 trisphosphate (InsP(3)) receptors (InsP(3)Rs).
Arnoult, Christophe, Cristiano Grasso, Treves, Susan, Ronjat, Michel, Mikoshiba, Katsuhiko, ARNOULT C, GRASSO C, TREVES, Susan Nella, Ducreux, Sylvie, DUCREUX S, Smida-Rezgui, Sophia, Franzini-Armstrong, Clara, MIKOSHIBA K, SCHRUM A, Sylvie Ducreux, Susan Treves, RONJAT M, Grasso, Cristiano, Zhu, Michael X., Zorzato, Francesco, SMIDA REZGUI S, Sophia Smida-Rezgui, MOCCAGATTA L, Zhu, Michael, Francesco Zorzato, Clara Franzini-Armstrong, Christophe Arnoult, Luca Moccagatta, Schrum, Adam, Michel Ronjat, ZHU MX, GIRARD T, Girard, Thierry, Katsuhiko Mikoshiba, Thierry Girard, FRANZINI ARMSTRONG C, Moccagatta, Luca, Michael X. Zhu, Adam Schrum   +38 more
core   +1 more source

Calmodulin binding proteins and neuroinflammation in multiple neurodegenerative diseases

BMC Neuroscience, 2022
Calcium dysregulation (“Calcium Hypothesis”) is an early and critical event in Alzheimer’s and other neurodegenerative diseases. Calcium binds to and regulates the small regulatory protein calmodulin that in turn binds to and regulates several hundred ...
Danton H. O’Day, Robert J. Huber
doaj   +1 more source

Membrane interactions of S100A12 (Calgranulin C) [PDF]

, 2013
S100A12 (Calgranulin C) is a small acidic calcium-binding peripheral membrane protein with two EF-hand structural motifs. It is expressed in macrophages and lymphocytes and highly up-regulated in several human inflammatory diseases.
Costa-Filho, A.J., Wallace, Bonnie A., Araujo, A.P.U., Hofmann, A., Garcia, A.F., Lopes, J.L.S.   +5 more
core   +1 more source

S100 Calcium-Binding Proteins and Ion Channels

Frontiers in Pharmacology, 2012
S100 Ca2+-binding proteins have been associated with a multitude of intracellular Ca2+-mediated functions including regulation of the cell cycle, cell differentiation, cell motility and apoptosis, modulation of membrane-cytoskeletal interactions ...
Anton eHermann, Rosario eDonato, Thomas M. Weiger, Walter J. Chazin   +3 more
doaj   +1 more source

Reviving lost binding sites: Exploring calcium‐binding site transitions between human and murine CD23

FEBS Open Bio, 2021
Immunoglobulin E (IgE) is a central regulatory and triggering molecule of allergic immune responses. IgE’s interaction with CD23 modulates both IgE production and functional activities.CD23 is a noncanonical immunoglobulin receptor, unrelated to ...
Veronica F. Ilkow, Anna M. Davies, Balvinder Dhaliwal, Andrew J. Beavil, Brian J. Sutton, James M. McDonnell   +5 more
doaj   +1 more source

Identification of CP12 as a Novel Calcium-Binding Protein in Chloroplasts

Plants, 2013
Calcium plays an important role in the regulation of several chloroplast processes. However, very little is still understood about the calcium fluxes or calcium-binding proteins present in plastids.
Agostinho Gomes Rocha, Ute C. Vothknecht
doaj   +1 more source

An Update to Calcium Binding Proteins

, 2019
Ca2+ binding proteins (CBP) are of key importance for calcium to play its role as a pivotal second messenger. CBP bind Ca2+ in specific domains, contributing to the regulation of its concentration at the cytosol and intracellular stores. They also participate in numerous cellular functions by acting as Ca2+ transporters across cell membranes or as Ca2+-
Jacobo Elíes, Matilde Yáñez, Thiago M. C. Pereira, José Gil-Longo, David A. MacDougall, Manuel Campos-Toimil   +5 more
openaire   +3 more sources

Calcium‐binding proteins in rat skin

FEBS Letters, 1987
Skin Ca2+‐binding protein (SCaBP) was reported to be distinct from the Ca2+‐binding parvalbumin (PV), however, more recently its amino acid sequence was shown to be identical to PV. We purified a protein (Mr12 000; pI4.5) from isolated epidermis (free of other cell layers) of adult rats and whole skin (containing no PV) of newborn rats. This protein is
Schelling, Claude P., Didierjean, Liliane, Rizk, Marthe, Pavlovitch, Jana H., Takagi, Takashi, Heizmann, Claus W.   +5 more
openaire   +2 more sources

s-cyclophilin is retained intracellularly via a unique COOH-terminal sequence and colocalizes with the calcium storage protein calreticulin [PDF]

, 1992
Cyclophilins (cyclosporin A-binding proteins) are conserved, ubiquitous, and abundant proteins that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins in vitro.
Arber, S., P Caroni, Krause, Karl-Heinz, K H Krause, S Arber, Caroni, P., Krause, K. H.   +6 more
core   +1 more source