Scientific Reports, 2021 Increasing evidence has indicated that adult neurogenesis contributes to brain plasticity, although function of new neurons is still under debate. In opossums, we performed an olfactory-guided behavior task and examined the association between olfactory ...
Beata Tepper +5 more
doaj +1 more source
Epigenetic Regulation of Epidermal Differentiation
Epigenomes, 2021 The epidermis is the outer part of the skin that protects the organism from dehydration and shields from external insults. Epidermal cells, called keratinocytes, undergo a series of morphological and metabolic changes that allow them to establish the ...
Wiesława Leśniak
doaj +1 more source
Early effects of LPS-induced neuroinflammation on the rat hippocampal glycolytic pathway
Journal of Neuroinflammation, 2022 Highlights LPS-induced neuroinflammation promotes metabolic reprogramming. Neuroinflammation increased glycolytic flow and lactate release. Inhibitors of different glycolytic reactions prevented the inflammatory response. S100B changes suggest a role for
Adriana Fernanda K. Vizuete +8 more
doaj +1 more source
Frontiers in Neuroanatomy, 2020 In therian mammals, the cerebellum is one of the late developing structures in the brain. Specifically, the proliferation of cerebellar granule cells occurs after birth, and even in humans, the generation of these cells continues during the first year of
Beata Tepper +6 more
doaj +1 more source
Calcium-Binding Proteins as Determinants of Central Nervous System Neuronal Vulnerability to Disease [PDF]
International Journal of Molecular Sciences, 2019 Richard Fairless, Ricarda Diem
exaly +2 more sources
On the calcium‐binding ability of the synthetic evolutionary ancestor of calcium‐binding proteins [PDF]
FEBS Letters, 1978 A number of calcium-binding proteins have a domain structure and the domain primary structures are rather similar. Parvalbumins have three domains, two of them are able to bind calcium [l] . Homology of this kind can be found in troponin C [2] and myosin alkali light chains [3] having four domains.
Maximov, E.E. +2 more
openaire +2 more sources
Insight into Calcium-Binding Motifs of Intrinsically Disordered Proteins
Biomolecules, 2021 Motifs within proteins help us categorize their functions. Intrinsically disordered proteins (IDPs) are rich in short linear motifs, conferring them many different roles.
Estella A. Newcombe +7 more
doaj +1 more source
Calcium binding activity of the epidermal growth factor-like domains of the apicomplexan microneme protein EtMIC4 [PDF]
, 2005 Microneme proteins are secreted from apicomplexan parasites during invasion of host cells and they play crucial roles in parasite-host cell adhesion.
Gill, A C +8 more
core +1 more source
Identification of Structural Calcium Binding Sites in Membrane-Bound Presenilin 1 and 2 [PDF]
, 2020 Variants of presenilin (PS1 and PS2) are the main genetic risk factors of familial Alzheimer's disease and thus central to the disease etiology. Although mostly studied as catalytic units of γ-secretase controlling Aβ production, presenilins also affect ...
Mehra, Rukmankesh +1 more
core +1 more source
Characterisation of Bombyx mori odorant-binding proteins reveals that a general odorant-binding protein discriminates between sex pheromone components [PDF]
, 2009 In many insect species, odorant-binding proteins (OBPs) are thought to be responsible for the transport of pheromones and other semiochemicals across the sensillum lymph to the olfactory receptors (ORs) within the antennal sensilla.
Field, L.M. +20 more
core +1 more source