Calmodulin Binding Domains in Critical Risk Proteins Involved in Neurodegeneration
Current Issues in Molecular Biology, 2022 Neurodegeneration leads to multiple early changes in cognitive, emotional, and social behaviours and ultimately progresses to dementia. The dysregulation of calcium is one of the earliest potentially initiating events in the development of ...
Danton H. O’Day
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Elucidating the mechanisms of cooperative calcium-calmodulin interactions: a structural systems biology approach [PDF]
, 2008 BACKGROUND: Calmodulin is an important multifunctional molecule that regulates the activities of a large number of proteins in the cell. Calcium binding induces conformational transitions in calmodulin that make it specifically active to particular ...
Najl V Valeyev +19 more
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Fungal genomes: suffering with functional annotation errors
IMA Fungus, 2021 Background The genome sequence data of more than 65985 species are publicly available as of October 2021 within the National Center for Biotechnology Information (NCBI) database alone and additional genome sequences are available in other databases and ...
Tapan Kumar Mohanta, Ahmed Al-Harrasi
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Calcium-binding capacity of organic and inorganic ortho- and polyphosphates [PDF]
, 2009 The aim of this research was to determine the calcium-binding capacity of inorganic and organic ortho- and polyphosphates. This calcium-binding capacity can be used to influence the stability of, for example, casein micelles in dairy systems.
Hooijdonk, A.C.M., van +4 more
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BMC Cardiovascular Disorders, 2018 Background Recent studies have shown a significant role of the endocannabinoid system, apelin and S100A6 protein in the regulation of cardiovascular system functioning.
Irena Kasacka +3 more
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Proteolysis of insulin-like growth factor binding proteins (IGFBPs) by calpain [PDF]
, 2005 Calpains are non-lysosomal, Ca2+-dependent cysteine proteases, which are ubiquitously distributed across cell types and vertebrate species. The rules that govern calpain specificity have not yet been determined.
Mann, Karlheinz +12 more
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Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function [PDF]
, 2009 Background Human S100A12 is a member of the S100 family of EF-hand calcium-modulated proteins that are associated with many diseases including cancer, chronic inflammation and neurological disorders.
Lednev, Igor K. +27 more
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Developmental and adult characterization of secretagogin expressing amacrine cells in zebrafish retina. [PDF]
PLoS ONE, 2017 Calcium binding proteins show stereotypical expression patterns within diverse neuron types across the central nervous system. Here, we provide a characterization of developmental and adult secretagogin-immunolabelled neurons in the zebrafish retina with
Stefanie Dudczig +2 more
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Effect of Calcium Deficiency on Growth and Leaf Acid Soluble Proteins of Tomato [PDF]
, 2007 The effects of temporary Ca (Ca) calcium deficiency lasting 2, 3, 4 or 5 d were investigated on tomato plants at the 6-leaf stage, grown hydroponically under controlled conditions.
Silvestre, Jérôme +3 more
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Characterization of the S100A1 protein binding site on TRPC6 C-terminus. [PDF]
PLoS ONE, 2013 The transient receptor potential (TRP) protein superfamily consists of seven major groups, among them the "canonical TRP" family. The TRPC proteins are calcium-permeable nonselective cation channels activated after the emptying of intracellular calcium ...
Jan Bily +6 more
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