Calcium Channel α<sub>2</sub>δ Ligands Mirogabalin, Pregabalin, and Gabapentin: Advancements in Diabetic Peripheral Neuropathic Pain Therapeutics. [PDF]
Wu Y, Guo X, Zhang J.
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Efficacy and safety of topical vs. oral calcium channel blockers for chronic anal fissures: a systematic review and meta-analysis. [PDF]
Li T, Ye P, He X, Li C, Xi L, Xi Z.
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Efficacy of Esaxerenone Plus a Renin-Angiotensin System Inhibitor or Calcium Channel Blocker for Nocturnal Hypertension: A Post Hoc Analysis. [PDF]
Kario K +5 more
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Development of nifedipine isosteres: an integrated approach to the design, synthesis, and biological assessment of calcium channel blockers. [PDF]
Zohny YM, Awad SM, Alsaidan O, Rabie MA.
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Biphasic effects on human atrial arrhythmogenicity of L-type calcium channel mutations associated with a Brugada/Short QT overlap syndrome - insights from a multiscale simulation study. [PDF]
Xiang Y, Hancox JC, Zhang H.
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The Ca2+ channel blockers, diltiazem, nifedipine, and vcrapamil, are now well-established members of the therapeutic armamentarium employed in cardiovascular disease including, but not limited to, angina in its several forms, hypertension, some cardiac arrhythmias including supraventricular tachycardia, congestive heart failure, and hypertrophic ...
D J, Triggle, R A, Janis
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Calcium, calcium channels, and calcium channel antagonists
Canadian Journal of Physiology and Pharmacology, 1990Voltage-dependent Ca2+ channels are an important pathway for Ca2+ influx in excitable cells. They also represent an important site of action for a therapeutic group of agents, the Ca2+ channel antagonists. These drugs enjoy considerable use in the cardiovascular area including angina, some arrhythmias, hypertension, and peripheral vascular disorders ...
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A key step in renal calcium reabsorption is dihydropyridine-sensitive calcium entry across the apical membrane of the distal tubule. Electrophysiologic studies have confirmed the existence of calcium channels that may mediate this pathway. Molecular studies of voltage-dependent calcium channels have revealed a surprising degree of heterogeneity.
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Calcium channels and calcium channel antagonists
Annals of Neurology, 1987AbstractChanges in free intracellular Ca2+ levels provide signals that allow nerve and muscle cells to respond to a host of external stimuli. A major mechanism for elevating the level of intracellular Ca2+ is the influx of extracellular Ca2+ through voltage‐dependent channels in the cell membrane.
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