Results 41 to 50 of about 464,946 (417)
Functional role of T-type calcium channels in tumour growth and progression: prospective in cancer therapy. [PDF]
, 2012 T-type Ca2+ channels represent a specific channel family overexpressed in different types of tumours. Their involvement in controlling the proliferation, angiogenesis and invasion of tumour cells, has been partially clarified. The article by Zhang et al.
NABISSI, MASSIMO +2 more
core +1 more source
Calcium channel antagonist and beta-blocker overdose: antidotes and adjunct therapies.
British Journal of Clinical Pharmacology, 2016 Management of cardiovascular instability resulting from calcium channel antagonist (CCB) or beta-adrenergic receptor antagonist (BB) poisoning follows similar principles. Significant myocardial depression, bradycardia and hypotension result in both cases.
A. Graudins, Hwee Min D Lee, D. Druda
semanticscholar +1 more source
Calcium channel blockers and dementia [PDF]
British Journal of Pharmacology, 2013 Degenerative dementia is mainly caused by Alzheimer's disease and/or cerebrovascular abnormalities. Disturbance of the intracellular calcium homeostasis is central to the pathophysiology of neurodegeneration. In Alzheimer's disease, enhanced calcium load may be brought about by extracellular accumulation of amyloid‐β.
Anne Eckert, V Nimmrich
openaire +3 more sources
Antiarrhythmic drug usage and prostate cancer: a population-based cohort study
Asian Journal of Andrology, 2018 Even though the relationship between antiarrhythmic drug usage and subsequent prostate cancer (PCa) risk has recently been highlighted, relevant findings in the previous literature are still inconsistent.
Li-Ting Kao +3 more
doaj +1 more source
A computational framework for pharmaco-mechanical interactions in arterial walls using parallel monolithic domain decomposition methods [PDF]
arXiv, 2023 A computational framework is presented to numerically simulate the effects of antihypertensive drugs, in particular calcium channel blockers, on the mechanical response of arterial walls. A stretch-dependent smooth muscle model by Uhlmann and Balzani is modified to describe the interaction of pharmacological drugs and the inhibition of smooth muscle ...
arxiv
Pain, 2015 T-type Cav3.2 calcium channels represent a novel target for neuropathic pain modulation. Preclinical studies with ABT-639, a peripherally acting highly selective T-type Cav3.2 calcium channel blocker, showed dose-dependent reduction of pain in multiple ...
D. Ziegler +4 more
semanticscholar +1 more source
Parasite, 2005 Culturing fresh clinical isolates of P. falciparum and using the isotopic method, we tested separately chloroquine and isradipine – a calcium channel blocker –, and also the combination isradipine plus chloroquine.
Randrianarivelojosia M., Jambou R.
doaj +1 more source
Phenytoin- and amlodipine-induced gingival overgrowth
Journal of Dental Sciences, 2012 Drug-induced gingival overgrowth is an adverse event associated with three types of drugs, i.e., anticonvulsants, immunosuppressants, and calcium-channel blockers.
Ching-Wen Chang +2 more
doaj +1 more source
An Open Framework to Model Diffraction by Dynamic Blockers in Millimeter Wave Simulations [PDF]
, 2022 The millimeter wave (mmWave) band will be exploited to address the growing demand for high data rates and low latency. The higher frequencies, however, are prone to limitations on the propagation of the signal in the environment. Thus, highly directional beamforming is needed to increase the antenna gain.
arxiv +1 more source
Calcium Channel Blocker Exposure in Late Pregnancy and the Risk of Neonatal Seizures
Obstetrics and Gynecology, 2015 OBJECTIVE: To assess whether maternal calcium channel blocker exposure during late pregnancy is independently associated with neonatal seizures after carefully controlling for confounding factors.
B. Bateman +10 more
semanticscholar +1 more source