Calcium Channel Blockers and Hypertension
Journal of Cardiovascular Pharmacology and Therapeutics, 2015 Effective treatment of high blood pressure (BP) represents a key strategy for reducing the burden of hypertension-related cardiovascular and renal diseases. In spite of these well-established concepts, hypertension remains poorly controlled worldwide.
G. Tocci +6 more
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Discovery and Development of Calcium Channel Blockers
Frontiers in Pharmacology, 2017 In the mid 1960s, experimental work on molecules under screening as coronary dilators allowed the discovery of the mechanism of calcium entry blockade by drugs later named calcium channel blockers. This paper summarizes scientific research on these small
Théophile Godfraind
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Calcium channel blockers- Induced iatrogenic gingival hyperplasia: Case series
Journal of Pharmacy and Bioallied Sciences, 2023 Hypertension rightfully termed as “Silent killer” is associated with increase in morbidity and mortality when left untreated. Calcium channel blockers are the most commonly prescribed first-line anti-hypertensive drugs in India.
G Agnes Golda Priyadarshini +4 more
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Telangiectasia Macularis Multiplex Acquisita and its Potential Association with Calcium Channel Blockers: A Retrospective Study of 46 Chinese Patients [PDF]
Acta Dermato-VenereologicaTelangiectasia macularis multiplex acquisita is an acquired cutaneous telangiectasis of unknown aetiology, and it lacks both effective and cost-efficient treatment.
Tian Chen +6 more
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Calcium Channel Blockers [PDF]
The Journal of Clinical Hypertension, 2011 KEY POINTS AND PRACTICAL RECOMMENDATIONS: • Calcium channel blockers, which dilate arteries by reducing calcium flux into cells, effectively lower blood pressure, especially in combination with other drugs, and some formulations of agents of this class are approved for treating angina or cardiac dysrhythmias.
W. Elliott, C. Ram
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The risk of second primary malignancies in colorectal cancer patients using calcium channel blockers [PDF]
Scientific Reports, 2023 Calcium channel blockers are among the most commonly used agents in the treatment of cardiovascular diseases. There are several known side-effects associated with their long-term use, whereas other potential adverse effects are yet to be proven.
Jana Halámková +13 more
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Calcium channel blockers and dementia [PDF]
British Journal of Pharmacology, 2013 Degenerative dementia is mainly caused by Alzheimer's disease and/or cerebrovascular abnormalities. Disturbance of the intracellular calcium homeostasis is central to the pathophysiology of neurodegeneration. In Alzheimer's disease, enhanced calcium load may be brought about by extracellular accumulation of amyloid‐β.
V. Nimmrich, A. Eckert
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Are calcium channel blockers related to lung cancer? [PDF]
Drug Target Insights, 2023 Background: Calcium channel blocker (CCB) is a common antihypertensive agent for the treatment of hypertension. There are inconsistent data of an association of CCB and lung cancer in the literature.
Ratchanon Rattanathanoo +5 more
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Calcium-Channel Blockers: An Alternative Therapy to Beta-Blockers for Myocardial Infarction? [PDF]
JACC Asia, 2023 Hao K, Yasuda S.
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The Evolving Role of Calcium Channel Blockers in Hypertension Management: Pharmacological and Clinical Considerations [PDF]
Current Issues in Molecular BiologyWorldwide, hypertension is the leading risk factor for cardiovascular disease and death. An estimated 122 million people, per the American Heart Association in 2023, have been diagnosed with this common condition.
Kamryn E. Jones +11 more
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