Results 41 to 50 of about 341,374 (309)
پزشکی بالینی ابن سینا, 2007 Background & Objective: Verapamil, nifedipine and diltiazem are calcium channel blockers widely used as a variety of cardiovascular ailment in humans. A number of studies have shown that calcium channel blockers have anticonvulsant effect in a range of ...
doaj
The fourth-generation Calcium channel blocker: Cilnidipine
Indian Heart Journal, 2013 Several classes of antihypertensive agents have been in clinical use, including diuretics, α-blockers, β-blockers, angiotensin converting enzyme (ACE) inhibitors, angiotensin II type 1 receptor blockers (ARB), and organic calcium channel blockers (CCBs).
K. Sarat Chandra, G. Ramesh
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Background Establishing the sex‐specific efficacy of cardiovascular medications is pivotal to evidence‐based clinical practice, potentially closing the gender gap in longevity. Trials large enough to establish sex differences are unavailable.
Man Ki Kwok, C. Mary Schooling
doaj +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
BETA-BLOCKERS IN THE TREATMENT OF ARTERIAL HYPERTENSION: EVIDENCE BASED DATA AND REAL PRACTICE
Рациональная фармакотерапия в кардиологии, 2015 Data of the largest meta-analyzes of beta-blockers use in arterial hypertension is presented. The role of beta-blockers among other basic groups of antihypertensive drugs (thiazide diuretics, calcium channel blockers, ACE inhibitors) is evaluated ...
M. V. Leonova
doaj +3 more sources
A Rare Case Report of Amlodipine-Induced Gingival Enlargement and Review of Its Pathogenesis
Case Reports in Dentistry, 2013 Gingival enlargement is a common clinical feature of gingival and periodontal diseases. It is an unwanted side effect of certain systemic drugs given for nondental treatment.
Sanjeev Joshi, Sucheta Bansal
doaj +1 more source
Pre-injury beta blocker use does not affect the hyperdynamic response in older trauma patients
Journal of Emergencies, Trauma and Shock, 2014 Purpose: Trauma dogma dictates that the physiologic response to injury is blunted by beta-blockers and other cardiac medications. We sought to determine how the pre-injury cardiac medication profile influences admission physiology and post-injury ...
David C Evans +8 more
doaj +1 more source
Managing new-onset atrial fibrillation in critically ill patients: a systematic narrative review
BMJ Open, 2020 Objectives The aim of this review is to summarise the latest evidence on efficacy and safety of treatments for new-onset atrial fibrillation (NOAF) in critical illness.Participants Critically ill adult patients who developed NOAF during admission.Primary
Oliver C Redfern +5 more
doaj +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Long-term effects of antihypertensive medications on bone mineral density in men older than 55 years
Clinical Interventions in Aging, 2014 Kamil Serkan Ağaçayak,1 Sedat Güven,2 Mahmut Koparal,1 Nedim Güneş,1 Yusuf Atalay,3 Serhat Atilgan11Department of Oral and Maxillofacial Surgery, 2Department of Prosthodontics, School of Dentistry, University of Dicle, Diyarbakir, Turkey;
Ağaçayak KS +5 more
doaj