Signaling complexes of voltage-gated calcium channels
Voltage gated calcium channels are key mediators of depolarization induced calcium entry into electrically excitable cells. There is increasing evidence that voltage gated calcium channels, like many other types of ionic channels, do not operate in ...
R. W. Turner+2 more
semanticscholar +1 more source
Voltage-activated calcium channels that must be phosphorylated to respond to membrane depolarization. [PDF]
David L. Armstrong, Roger Eckert
openalex +1 more source
Prions are transmissible pathogens that cause neurodegenerative diseases, although the mechanisms behind the nervous system dysfunctions are unclear.
Malin K Sandberg+3 more
doaj
Large Deviations of Piecewise-Deterministic-Markov-Processes with Application to Stochastic Calcium Waves [PDF]
We prove a Large Deviation Principle for Piecewise Deterministic Markov Processes (PDMPs). This is an asymptotic estimate for the probability of a trajectory in the large size limit. Explicit Euler-Lagrange equations are determined for computing optimal first-hitting-time trajectories.
arxiv
Ion Channels, Natural Nanovalves [PDF]
Ion channels are proteins with holes down their middle that control the flow of ions and electric current across otherwise impermeable biological membranes. The flow of sodium, potassium, calcium (divalent), and chloride ions have been central issues in biology for more than a century.
arxiv
Data-driven modelling of the inositol trisphosphate receptor (IPR) and its role in calcium induced calcium release (CICR) [PDF]
We give a review of the current state of the art of data-driven modelling of the inositol trisphosphate receptor (IPR). After explaining that the IPR plays a crucial role as a central regulator in calcium dynamics, several sources of relevant experimental data are introduced.
arxiv
Inhibition of calcium channels by harmaline and other harmala alkaloids in vascular and intestinal smooth muscles [PDF]
Hideaki Karaki, T. Kishimoto, H Ozaki
openalex +1 more source
The multifaceted role of calcium signaling dynamics in neural cell proliferation and gliomagenesis
Calcium (Ca2+) signaling plays a pivotal role in coordinating neural stem cell (NSC) proliferation across various cell cycle stages, regulating immediate early gene transcription, and governing processes like quiescence and cell division.
Ola A Al-Ewaidat +3 more
doaj +1 more source
Inward rectifier potassium channels interact with calcium channels to promote robust and physiological bistability [PDF]
In the dorsal horn, projection neurons play a significant role in pain processing by transmitting sensory stimuli to supraspinal centers during nociception. Following exposure to intense noxious stimuli, a sensitization process occurs to adapt the dorsal horn functional state.
arxiv
An intracellular calcium frequency code model extended to the Riemann zeta function [PDF]
We have used the Nernst chemical potential treatment to couple the time domains of sodium and calcium ion channel opening and closing rates to the spatial domain of the diffusing waves of the travelling calcium ions inside single cells. The model is plausibly evolvable with respect to the origins of the molecular components and the scaling of the ...
arxiv