Results 101 to 110 of about 3,302,136 (284)

Signaling complexes of voltage-gated calcium channels

Channels, 2011
Voltage gated calcium channels are key mediators of depolarization induced calcium entry into electrically excitable cells. There is increasing evidence that voltage gated calcium channels, like many other types of ionic channels, do not operate in ...
R. W. Turner, Dustin Anderson, G. Zamponi   +2 more
semanticscholar   +1 more source

Voltage-activated calcium channels that must be phosphorylated to respond to membrane depolarization. [PDF]

, 1987
David L. Armstrong, Roger Eckert
openalex   +1 more source

Scrapie-infected GT1-1 cells show impaired function of voltage-gated N-type calcium channels (Cav 2.2) which is ameliorated by quinacrine treatment

Neurobiology of Disease, 2004
Prions are transmissible pathogens that cause neurodegenerative diseases, although the mechanisms behind the nervous system dysfunctions are unclear.
Malin K Sandberg, Peter Wallén, Martin A Wikström, Krister Kristensson   +3 more
doaj  

Large Deviations of Piecewise-Deterministic-Markov-Processes with Application to Stochastic Calcium Waves [PDF]

arXiv
We prove a Large Deviation Principle for Piecewise Deterministic Markov Processes (PDMPs). This is an asymptotic estimate for the probability of a trajectory in the large size limit. Explicit Euler-Lagrange equations are determined for computing optimal first-hitting-time trajectories.
arxiv  

Ion Channels, Natural Nanovalves [PDF]

arXiv, 2012
Ion channels are proteins with holes down their middle that control the flow of ions and electric current across otherwise impermeable biological membranes. The flow of sodium, potassium, calcium (divalent), and chloride ions have been central issues in biology for more than a century.
arxiv  

Data-driven modelling of the inositol trisphosphate receptor (IPR) and its role in calcium induced calcium release (CICR) [PDF]

arXiv, 2015
We give a review of the current state of the art of data-driven modelling of the inositol trisphosphate receptor (IPR). After explaining that the IPR plays a crucial role as a central regulator in calcium dynamics, several sources of relevant experimental data are introduced.
arxiv  

Inhibition of calcium channels by harmaline and other harmala alkaloids in vascular and intestinal smooth muscles [PDF]

, 1987
Hideaki Karaki, T. Kishimoto, H Ozaki
openalex   +1 more source

The multifaceted role of calcium signaling dynamics in neural cell proliferation and gliomagenesis

AIMS Biophysics
Calcium (Ca2+) signaling plays a pivotal role in coordinating neural stem cell (NSC) proliferation across various cell cycle stages, regulating immediate early gene transcription, and governing processes like quiescence and cell division.
Ola A Al-Ewaidat , Sopiko Gogia, Valiko Begiashvili, Moawiah M Naffaa   +3 more
doaj   +1 more source

Inward rectifier potassium channels interact with calcium channels to promote robust and physiological bistability [PDF]

arXiv
In the dorsal horn, projection neurons play a significant role in pain processing by transmitting sensory stimuli to supraspinal centers during nociception. Following exposure to intense noxious stimuli, a sensitization process occurs to adapt the dorsal horn functional state.
arxiv  

An intracellular calcium frequency code model extended to the Riemann zeta function [PDF]

arXiv, 2019
We have used the Nernst chemical potential treatment to couple the time domains of sodium and calcium ion channel opening and closing rates to the spatial domain of the diffusing waves of the travelling calcium ions inside single cells. The model is plausibly evolvable with respect to the origins of the molecular components and the scaling of the ...
arxiv