Results 251 to 260 of about 475,886 (304)

Voltage-gated calcium channels in genetic epilepsies. [PDF]

J Neurochem
Lauerer RJ, Lerche H.
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A bi-directional binding site linking the α₂δ-1 subunit to the intrinsic speed control process in VSD I of voltage-gated calcium channels

Heiss MC, Fernández-Quintero ML, Kranbitter N, Aouad HE, Campiglio M, Flucher BE.   +5 more
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Nanoscale organization of cardiac calcium channels is dependent on thyroid hormone status.

Am J Physiol Heart Circ Physiol
Charest A, Nasta N, Siddiqui S, Menkes S, Thomas A, Saad D, Forman J, Huang X, Sison CP, Gerdes AM, Stout RF, Ojamaa K.   +11 more
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Calcium Channel Ligands

Annual Review of Pharmacology and Toxicology, 1987
The Ca2+ channel blockers, diltiazem, nifedipine, and vcrapamil, are now well-established members of the therapeutic armamentarium employed in cardiovascular disease including, but not limited to, angina in its several forms, hypertension, some cardiac arrhythmias including supraventricular tachycardia, congestive heart failure, and hypertrophic ...
D J, Triggle, R A, Janis
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Calcium, calcium channels, and calcium channel antagonists

Canadian Journal of Physiology and Pharmacology, 1990
Voltage-dependent Ca2+ channels are an important pathway for Ca2+ influx in excitable cells. They also represent an important site of action for a therapeutic group of agents, the Ca2+ channel antagonists. These drugs enjoy considerable use in the cardiovascular area including angina, some arrhythmias, hypertension, and peripheral vascular disorders ...
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Calcium channels

Current Opinion in Nephrology and Hypertension, 1994
A key step in renal calcium reabsorption is dihydropyridine-sensitive calcium entry across the apical membrane of the distal tubule. Electrophysiologic studies have confirmed the existence of calcium channels that may mediate this pathway. Molecular studies of voltage-dependent calcium channels have revealed a surprising degree of heterogeneity.
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Calcium channels and calcium channel antagonists

Annals of Neurology, 1987
AbstractChanges in free intracellular Ca2+ levels provide signals that allow nerve and muscle cells to respond to a host of external stimuli. A major mechanism for elevating the level of intracellular Ca2+ is the influx of extracellular Ca2+ through voltage‐dependent channels in the cell membrane.
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Calcium channel blockers and calcium channels

2004
In 1883, Ringer showed that to get isolated hearts to contract, it was necessary to have Ca2+ ions in the perfusion medium [421]. This was the first demonstration of the critical role of calcium in cellular activity. Remarkably, a hundred years passed before the importance of calcium was recognized in processes other than muscle contraction, and almost
Eric Ertel, Théophile Godfraind
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Calcium channel activation stabilizes a neuronal calcium channel mRNA

Nature Neuroscience, 1999
We have identified a calcium-dependent pathway in neurons that regulates expression levels of the alpha1B subunit and N channel current. When neurons are depolarized and voltage-gated calcium channels activated, the half-life of cellular N channel alpha1B mRNA is prolonged.
S, Schorge, S, Gupta, Z, Lin, M W, McEnery, D, Lipscombe   +4 more
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