Results 231 to 240 of about 3,686,002 (351)

Spatiotemporal Drug Delivery via a Neonatal Spinal Cord ECM Hydrogel for Biomimetic Microenvironment Remodeling After Spinal Cord Injury

Advanced Functional Materials, EarlyView.
A biomimetic hydrogel derived from neonatal spinal cord ECM (DNSCM) delivers LAMB2 protein and ISP peptide to remodel the inhibitory injury microenvironment. The system sustains drug release, upregulates pro‐regenerative LAMB2, downregulates inhibitory CSPG, and promotes axonal regeneration.
Shiyu Fu, Liangchao Du, Runlin Wen, Kai Zhang, Yu Zhou, Wanrong Ma, Zhiquan Yang, Dingyang Liu, Xing Li   +8 more
wiley   +1 more source

Intracellular calcium channels: Potential targets for type 2 diabetes mellitus? [PDF]

World J Diabetes
Zhu JX, Pan ZN, Li D.
europepmc   +1 more source

Nanoengineered Binetworks in Multifunctional Anionic Block Polymer Mesoblends for Improved Mechanical Properties

Advanced Functional Materials, EarlyView.
Mesoblends consist of a nanostructured polymer into which a second polymer is imbibed with a selective solvent. In this work, a solvent‐templatable pentablock terpolymer possessing a sulfonated midblock is modified with a hydrophilic polymer that is photocrosslinked in situ, yielding a hierarchical binetwork.
Kacie M. Wells, Ivan Kuzmenko, Reza A. Ghiladi, Richard J. Spontak   +3 more
wiley   +1 more source

Degradation of voltage-gated calcium channels: mechanisms and applications in neurological and cardiovascular diseases. [PDF]

Cell Commun Signal
Liu L, Zhou Y, Liao P, Soong TW, Hu Z.
europepmc   +1 more source

Mechanoluminescent HOF Nanotransducers Enabled Sono‐Optogenetics in Parkinsonian Rats

Advanced Functional Materials, EarlyView.
We present a mechanoluminescent system utilizing porous hydrogen‐bonded organic frameworks (HOFs) as a toolkit for focused ultrasound‐triggered, non‐invasive light delivery to the deep brain in rats. This approach enables the specific activation of PV‐GPe neurons in dopamine‐depleted Parkinson's disease rat models, resulting in a comparable alleviation
Wenliang Wang, Ilya Pyatnitskiy, Yanshu Shi, Kai Wing Kevin Tang, Yi Xie, Sihan Yu, Thomas Wynn, Xiangping Liu, Ju‐Chun Hsieh, Jinmo Jeong, Weilong He, Brinkley Artman, Anakaren Romero Lozano, Xi Shi, Arjun Sangani, Lief E Fenno, Samantha Santacruz, Banglin Chen, Huiliang Wang   +18 more
wiley   +1 more source

Differential contribution of T-type voltage-gated calcium channels to vascular reactivity in the aorta and renal artery of healthy rabbits. [PDF]

Exp Physiol
Suarez A, Guerra-Ojeda S, Zarzoso M, Serna-García M, Vila JM, Serna E, Mauricio MD.   +6 more
europepmc   +1 more source

Designed Lewis Acid–Base Passivation for High Performance Perovskite Solar Cells

Advanced Functional Materials, EarlyView.
ABSTRACT Silicon's high cost and long energy payback time remain major barriers to the global expansion of solar power. In contrast, metal–halide perovskites offer abundant, solution‐processable absorbers, and have achieved efficiencies of 25%–30%, positioning them as strong competitors to silicon.
Afna Manaf, Hiba Shahulhameed, Bhabani Sankar Swain, Shengzhong (Frank) Liu, Adel Najar   +4 more
wiley   +1 more source

Ca_V3.3 T-type calcium channels contribute to carboplatin resistance in retinoblastoma. [PDF]

J Biol Chem
Kim S, Cho CS, Jang HY, Jo DH, Kim JH.
europepmc   +2 more sources

In Silico identification and modelling of FDA-approved drugs targeting T-type calcium channels. [PDF]

PLoS One
Fong P, Garcia SR, Stefan MI, Sterratt DC.   +3 more
europepmc   +1 more source

T-type calcium channels in burst-firing, network synchrony, and epilepsy.

Biochimica et Biophysica Acta, 2013
S. Cain, T. Snutch
semanticscholar   +1 more source